“ANTIBIOTICS PRACTICE QUESTIONS EXAM
2026 ”LATEST EXAM 2026 – 2027 SOLVED
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Antibiotics Practice Questions Exam
Which of the following antibiotics requires the patient to avoid calcium, iron,
or antacids because they interfere with absorption?
A. Fluoroquinolones
B. Sulphonamides
C. Aminoglycosides
D. Macrolides
A. Fluoroquinolones
A patient is taking nitrofurantoin for a UTI. Which finding requires immediate
follow-up?
A. Brown-coloured urine
B. Mild headache
C. Shortness of breath and cough
D. Nausea after the first dose
C. Shortness of breath and cough
A patient taking penicillin reports a history of throat swelling and hives during
a past dose. Which action is most appropriate?
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A. Administer the dose and monitor closely
B. Give with food to reduce GI upset
C. Avoid penicillin and avoid cephalosporins as well
D. Premedicate with diphenhydramine
C. Avoid penicillin and avoid cephalosporins as well
Which of the following drugs carries a major risk of QT prolongation?
A. Ceftriaxone
B. Macrolides
C. Clindamycin
D. Vancomycin
B. Macrolides
Which medication is used for severe infections but carries a risk of seizures,
especially at high doses?
A. Carbapenems
B. Cephalosporins
C. Sulfonamides
D. Tetracyclines
A. Carbapenems
Which patient is MOST at risk for developing a superinfection?
A. A patient taking a narrow-spectrum antibiotic for strep throat
B. A patient who just completed a 3-day antiviral regimen
C. A patient on long-term broad-spectrum antibiotic therapy
D. A patient receiving a single dose of prophylactic antibiotics before surgery
C. A patient on long-term broad-spectrum antibiotic therapy
Which of the following are common toxicities or adverse effects of
aminoglycosides?
Select all that apply.
A. Nephrotoxicity
B. Ototoxicity
C. Bone marrow suppression
D. Neuromuscular blockade
E. Photosensitivity
F. Serotonin syndrome
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A. Nephrotoxicity
B. Ototoxicity
D. Neuromuscular blockade
Which instructions should the nurse include when teaching a patient taking
sulfonamides? Select all that apply.
A. Drink 2-3 L of water/day
B. Avoid sunlight or use sunscreen
C. Expect tooth discoloration
D. Report any rash immediately
E. Avoid dairy products
F. Monitor CBC
A. Drink 2-3 L of water/day
B. Avoid sunlight or use sunscreen
D. Report any rash immediately
F. Monitor CBC
Which antibiotics can cause QT prolongation? Select all that apply.
A. Macrolides
B. Fluoroquinolones
C. Tetracyclines
D. Vancomycin
E. Clindamycin
F. Metronidazole
A. Macrolides
B. Fluoroquinolones
A patient taking an antibiotic develops flank pain and cloudy urine. Which drug
is most likely responsible?
A. Sulfamethoxazole-trimethoprim
B. Azithromycin
C. Vancomycin
D. Nitrofurantoin
A. Sulfamethoxazole-trimethoprim
Which of the following antibiotics ALSO interacts with calcium and iron, in
addition to tetracyclines?
A. Macrolides
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B. Fluoroquinolones
C. Penicillins
D. Carbapenems
B. Fluoroquinolones
Which antibiotic class requires patients to drink 2-3 liters of water per day to
prevent crystalluria?
A. Cephalosporins
B. Sulfonamides
C. Macrolides
D. Tetracyclines
B. Sulfonamides
Which of the following BEST describes bacteriostatic medications?
A. They kill bacteria directly.
B. They inhibit bacterial growth.
C. They destroy the bacterial cell wall.
D. They cause bacterial DNA to fragment.
B. They inhibit bacterial growth.
Which of the following BEST describes bactericidal medications?
A. They kill bacteria directly.
B. They inhibit bacterial growth.
C. They destroy the bacterial cell wall.
D. They cause bacterial DNA to fragment.
A. They kill bacteria directly.
Which antimicrobial class works by inhibiting folic acid synthesis?
A. Penicillins
B. Macrolides
C. Sulfonamides
D. Aminoglycosides
C. Sulfonamides
A patient who is receiving intravenous ciprofloxacin for pneumonia develops
diarrhea. A stool culture is positive for Clostridium difficile. The nurse will
expect the provider to:
a. restrict dairy products.