Page 1 of 145
“LILLEY'S PHARMACOLOGY 4TH EDITION 2026
”LATEST EXAM 2026 – 2027 SOLVED
QUESTIONS & ANSWERS VERIFIED 100%
GRADED A+ (LATEST VERSION) WELL REVISED
100% GUARANTEE PASS
Lilley's Pharmacology 4th Edition TEST BANK (Final Comprehensive Textbook
bank)
Phenytoin (Dilantin) has a narrow therapeutic index. Which statement defines
this characteristic?
The safe and toxic plasma levels are very close.
Phenytoin has a narrow chance of being effective.
No difference exists between safe and toxic plasma levels.
A very small dosage can result in the desired therapeutic effect.
The safe and toxic plasma levels are very close.
, Page 2 of 145
A narrow therapeutic index means that a narrow difference exists between safe and
toxic drug levels. These drugs require monitoring of therapeutic plasma levels.
A patient has been taking gabapentin (Neurontin®) for several years as part of
the treatment for partial seizures. His wife has called because he ran out of
medication this morning, and she wonders whether he can go without it for a
week until she can go to the drugstore. Which statement is true in this
situation?
Because the patient is taking another antiepileptic drug, he can go a week
without the gabapentin.
Stopping this medication abruptly may cause withdrawal seizures.
The patient should temporarily increase the dosage of his other medications.
The patient can probably stop all medication because he has been treated for
several years now.
Stopping this medication abruptly may cause withdrawal seizures.
Abrupt discontinuation of the gabapentin can lead to withdrawal seizures.
Which statements about antiepileptic drug (AED) therapy are true? (Select all
that apply.)
AED therapy can be stopped when seizures are under control.
AED therapy is usually lifelong.
Consistent dosing is key to control of seizures.
A dose may be skipped if the patient is experiencing adverse effects.
, Page 3 of 145
Abrupt withdrawal from AEDs may cause rebound seizure activity.
AED therapy is usually lifelong.
Consistent dosing is key to control of seizures.
Abrupt withdrawal from AEDs may cause rebound seizure activity.
Patients need to know that AED therapy is usually lifelong, and compliance (with
consistent dosing) is important for effective seizure control. Antiepileptic drugs must
never be abruptly discontinued as it may precipitate rebound seizure activity.
A patient has been taking selegiline (Anipril) for a month and says he
understands the "cheese effect" that the doctor explained to him. When the
nurse questions him about it, he tells her (correctly) that the cheese effect
results in which symptom?
Hypotension
Hypertension
Urinary discomfort
Gastrointestinal upset
Hypertension
The cheese effect causes severe hypertension. This is a major adverse effect of
monoamine oxidase inhibitors (MAOIs) because they interact with tyramine-
containing foods (cheese, red wine, beer, and yogourt).
A patient newly diagnosed with Parkinson's disease has been given a
prescription for levodopa-carbidopa (Sinemet®). The patient comments,
however, that a friend was given a prescription for "plain levodopa." What
should the nurse explain to this patient about her prescription?
Levodopa alone cannot cross the blood-brain barrier.
, Page 4 of 145
There is no real difference between the two prescriptions.
The combination drug is more efficient in increasing the dopamine level in the
brain.
Concerns about drug-food interactions with levodopa therapy do not exist with
the combination therapy.
The combination drug is more efficient in increasing the dopamine level in the brain.
The addition of carbidopa allows for more of the levodopa to reach the site of action
without being broken down. Thus, lower doses of levodopa are needed, and the
combination is more efficient in increasing the dopamine level in the brain.
Dopamine, unlike levodopa, cannot cross the blood-brain barrier. Drug-food
interactions with levodopa therapy alone are not a concern. If a substance interacts
with levodopa, it will also interact with the combination of levodopa-carbidopa
because the levodopa is the common component in both drugs.
When a patient is taking an anticholinergic, such as benztropine, as part of
treatment for Parkinson's disease, what important information should the
nurse give the patient as part of the teaching plan?
Avoid vitamin B6 supplements and vitamin-fortified foods.
Discontinue the medication immediately if adverse effects occur.
Take the medication on an empty stomach to enhance absorption.
Take the medication at bedtime to prevent drowsiness during the day.
Take the medication at bedtime to prevent drowsiness during the day.
Anticholinergics should be taken at bedtime to prevent drowsiness during the day.
Vitamin B6 interferes with dopaminergics, not anticholinergics. Anticholinergics
should not be discontinued suddenly and should be taken with or after meals in order
to minimize gastrointestinal upset.
“LILLEY'S PHARMACOLOGY 4TH EDITION 2026
”LATEST EXAM 2026 – 2027 SOLVED
QUESTIONS & ANSWERS VERIFIED 100%
GRADED A+ (LATEST VERSION) WELL REVISED
100% GUARANTEE PASS
Lilley's Pharmacology 4th Edition TEST BANK (Final Comprehensive Textbook
bank)
Phenytoin (Dilantin) has a narrow therapeutic index. Which statement defines
this characteristic?
The safe and toxic plasma levels are very close.
Phenytoin has a narrow chance of being effective.
No difference exists between safe and toxic plasma levels.
A very small dosage can result in the desired therapeutic effect.
The safe and toxic plasma levels are very close.
, Page 2 of 145
A narrow therapeutic index means that a narrow difference exists between safe and
toxic drug levels. These drugs require monitoring of therapeutic plasma levels.
A patient has been taking gabapentin (Neurontin®) for several years as part of
the treatment for partial seizures. His wife has called because he ran out of
medication this morning, and she wonders whether he can go without it for a
week until she can go to the drugstore. Which statement is true in this
situation?
Because the patient is taking another antiepileptic drug, he can go a week
without the gabapentin.
Stopping this medication abruptly may cause withdrawal seizures.
The patient should temporarily increase the dosage of his other medications.
The patient can probably stop all medication because he has been treated for
several years now.
Stopping this medication abruptly may cause withdrawal seizures.
Abrupt discontinuation of the gabapentin can lead to withdrawal seizures.
Which statements about antiepileptic drug (AED) therapy are true? (Select all
that apply.)
AED therapy can be stopped when seizures are under control.
AED therapy is usually lifelong.
Consistent dosing is key to control of seizures.
A dose may be skipped if the patient is experiencing adverse effects.
, Page 3 of 145
Abrupt withdrawal from AEDs may cause rebound seizure activity.
AED therapy is usually lifelong.
Consistent dosing is key to control of seizures.
Abrupt withdrawal from AEDs may cause rebound seizure activity.
Patients need to know that AED therapy is usually lifelong, and compliance (with
consistent dosing) is important for effective seizure control. Antiepileptic drugs must
never be abruptly discontinued as it may precipitate rebound seizure activity.
A patient has been taking selegiline (Anipril) for a month and says he
understands the "cheese effect" that the doctor explained to him. When the
nurse questions him about it, he tells her (correctly) that the cheese effect
results in which symptom?
Hypotension
Hypertension
Urinary discomfort
Gastrointestinal upset
Hypertension
The cheese effect causes severe hypertension. This is a major adverse effect of
monoamine oxidase inhibitors (MAOIs) because they interact with tyramine-
containing foods (cheese, red wine, beer, and yogourt).
A patient newly diagnosed with Parkinson's disease has been given a
prescription for levodopa-carbidopa (Sinemet®). The patient comments,
however, that a friend was given a prescription for "plain levodopa." What
should the nurse explain to this patient about her prescription?
Levodopa alone cannot cross the blood-brain barrier.
, Page 4 of 145
There is no real difference between the two prescriptions.
The combination drug is more efficient in increasing the dopamine level in the
brain.
Concerns about drug-food interactions with levodopa therapy do not exist with
the combination therapy.
The combination drug is more efficient in increasing the dopamine level in the brain.
The addition of carbidopa allows for more of the levodopa to reach the site of action
without being broken down. Thus, lower doses of levodopa are needed, and the
combination is more efficient in increasing the dopamine level in the brain.
Dopamine, unlike levodopa, cannot cross the blood-brain barrier. Drug-food
interactions with levodopa therapy alone are not a concern. If a substance interacts
with levodopa, it will also interact with the combination of levodopa-carbidopa
because the levodopa is the common component in both drugs.
When a patient is taking an anticholinergic, such as benztropine, as part of
treatment for Parkinson's disease, what important information should the
nurse give the patient as part of the teaching plan?
Avoid vitamin B6 supplements and vitamin-fortified foods.
Discontinue the medication immediately if adverse effects occur.
Take the medication on an empty stomach to enhance absorption.
Take the medication at bedtime to prevent drowsiness during the day.
Take the medication at bedtime to prevent drowsiness during the day.
Anticholinergics should be taken at bedtime to prevent drowsiness during the day.
Vitamin B6 interferes with dopaminergics, not anticholinergics. Anticholinergics
should not be discontinued suddenly and should be taken with or after meals in order
to minimize gastrointestinal upset.
