Immunology Exam 1 Questions With Correct Answers.

Immunology Exam 1 Questions With Correct
Answers

What |are |two |examples |of |phagocytes? |- |CORRECT |ANSWER✔✔-Neutrophils |(PMN-
polymorpho |nuclear) |and |Macrophages |(MO)

True |or |false: |Monocytes |are |precursors |of |macrophages. |- |CORRECT |ANSWER✔✔-True. |
Monocytes |are |found |in |blood |but |when |they |move |into |tissues, |they |are |macrophages.

What |cells |are |important |for |parasite |control, |allergy, |and |inflammation? |- |CORRECT |
ANSWER✔✔-1. |mast |cell |(release |histamine |when |activated)

2. |eosinophil |(similar |function |as |mast |cell |but |arrive |at |scene |later)

3. |basophil |(uncommon; |function |unknown)

4. |dendritic |cell |(internalize |pathogens |& |active |T-cells |& |help |initiate |adaptive |immune |
response-serving |as |a |bridge)

What |are |two |types |of |lymphocytes? |- |CORRECT |ANSWER✔✔-T |cells |and |B |cells.

T |or |F: |Plasma |cells |are |B-cells |that |actively |secrete |antibodies. |- |CORRECT |ANSWER✔✔-True.

What |is |the |effector |function? |- |CORRECT |ANSWER✔✔-A |job |that |a |cell |has |once |it |is |
activated

Some |functions |of |the |immune |response |include: |- |CORRECT |ANSWER✔✔-a. |recognition |of |
the |pathogen |or |antigen

b. |develop |"effector" |function

What |are |the |main |differences |between |innate |immunity |and |adaptive |immunity? |- |CORRECT |
ANSWER✔✔-Innate |immunity: |quicker |response, |use |less |specific |mechanisms |to |recognize |
pathogens, |unable |to |eradicate |the |pathogen |completely, |doesn't |provide |immunity |for |
reinfection.

Define |hematopoiesis. |- |CORRECT |ANSWER✔✔-Hematopoiesis |is |the |generation |of |blood |cells.

T |or |F: |Blood |cells |and |certain |tissue |cells |derive |from |a |common |hematopoietic |stem |cell. |- |
CORRECT |ANSWER✔✔-True. |It's |pluripotent |& |self-renewing |(can |make |many |copies |of |itself)

, Immune |cells |go |through |which |pathways? |- |CORRECT |ANSWER✔✔-Lymphoid |and |myeloid |
pathways.

What |are |examples |of |granulocytes? |- |CORRECT |ANSWER✔✔-neutrophils, |basophils, |and |
eosinophils. |They |are |polymorphonuclear |leukocytes |that |reside |in |the |blood.

What |chemical |signals |drive |the |path |the |cell |takes |to |its |final |fate? |- |CORRECT |ANSWER✔✔-1.
|colony |stimulating |factor |(CSF) |- |GCSF |(granulocyte |colony |stimulating |factor) |--> |drives |the |


production |of |neutrophils

2. |cytokines

3. |growth |factors

Blood |cell |development |occurs |where |in |the |body? |- |CORRECT |ANSWER✔✔-fetal |liver |or |
spleen, |and |bone |marrow |(adults |only)

What |does |lymphoid |progenitor |differentiate |into? |- |CORRECT |ANSWER✔✔-1. |B |cells

2. |T |cells

3. |Natural |Killer |(NK) |cells

What |does |myeloid |progenitor |differentiate |into? |- |CORRECT |ANSWER✔✔-1. |basophils

2. |eosinophils

3. |neutrophils

4. |mast |cells

5. |dendritic |cells

6. |monocytes

What |are |the |primary |lymphoid |tissues? |- |CORRECT |ANSWER✔✔-bone |marrow |and |thymus. |
Sites |where |the |lymphocytes/leukocytes |develop.

What |are |the |secondary |lymphoid |tissues? |- |CORRECT |ANSWER✔✔-sites |where |lymphocytes |
are |activated |to |respond |to |pathogens |include |the |spleen, |lymph |nodes, |tonsil/adenoids, |
malt/balt/galt |(mucosal/bronchial/gut |associated |lymphoid |tissues); |"dynamic" |tissues |bc |
lymphocytes |are |constantly |arriving |and |departing |& |"sampling" |the |environment |in |secondary
|tissue |to |see |if |they |need |to |respond |to |a |pathogen.



What's |the |significance |of |lymph |nodes? |- |CORRECT |ANSWER✔✔-it |is |where |lymphocytes |are |
activated |by |antigens