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NR283 Pathophysiology – Exam 1 Questions with Verified Answers

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This document contains verified questions and correct answers for Exam 1 of the NR283 Pathophysiology course. It covers foundational concepts including cell injury and adaptation, inflammation, tissue repair, fluid and electrolyte balance, acid-base disturbances, and introductory disease mechanisms, aligned with early course objectives.

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Uploaded on
January 20, 2026
Number of pages
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Written in
2025/2026
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NR 283
PATHOPHYSIOLOGY
EXAM 1 QUESTIONS
AND VERIFIED
ANSWERS

, NR 283 PATHOPHYSIOLOGY EXAM 1 QUESTIONS
AND VERIFIED ANSWERS
1st line of defense - - Answer --Barriers: Skin, Mucous Membranes, Gastric juices, Normal
Flora, and Cilia

2nd line of defense - - Answer --Inflammation and Phagocytosis

3rd line of defense - - Answer --B-Cells and T-Cells

Active artificial immunity - - Answer --immunizations

Active Immunity - - Answer --activates the immune system

Active natural immunity - - Answer --natural exposure to antigen

Apoptosis - - Answer --Programmed cell death, normal occurrence in the body

Atrophy - - Answer --Decrease in the size of the cells, results in reduced tissue mass

Autosomal Dominant Disorders - - Answer --Only takes one gene for disease to show. There
are no carriers, either have disease or don't. Marfan Syndrome, Huntington's, Familial
Hypercholesterolemia

Autosomal Recessive Disorders - - Answer --Has to have two recessive genes to have disease,
only one recessive gene to be carrier ex: Cystic fibrosis, PKU (phenylketonuria), Tay-Sachs

B-Cells - - Answer --Responsible for production of antibodies, can clone themselves to tag
antigens, can become memory B-cells to remember antigen(pathogen)

Blood pH - - Answer --7.35-7.45

Blood pH less than 7.35 - - Answer --metabolic or respiratory acidosis

Blood pH more than 7.45 - - Answer --metabolic or respiratory alkalosis

Ca2+ Normal Range - - Answer --8.5-10.5 mEq/L

Chromosomal Disorder - - Answer --not inherited, theres a problem on the chromosome

Cl- Normal Range - - Answer --98-106 mEq/L

Co2 normal range - - Answer --45-35

Cycle of Infection - - Answer --Pathogens, Reservoir, Portal of Exit, Mode of Transmission,
Portal of Entry, Host B

Cystic fibrosis - - Answer --autosomal recessive disorder that causes thick mucous secretions

Down's Syndrome - - Answer --Trisomy 21
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