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HESI Pharmacology Final Exam Review – Complete Study Guide, High-Yield Questions & Key Drug Concepts | Pass Your HESI Exam Fast

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Ace your HESI Pharmacology Final Exam with this complete, exam-focused study guide, designed to cover all critical drug and medication concepts. From pharmacokinetics and pharmacodynamics to major drug classes, side effects, and nursing considerations, this guide simplifies complex topics into clear, easy-to-understand notes. Perfect for first-time students and last-minute review, it ensures efficient studying and high retention of the most important information for exam success. This review emphasizes all high-yield pharmacology topics commonly tested on the HESI, including cardiovascular, respiratory, CNS, endocrine, GI, and antimicrobial medications, as well as safe dosage calculations, routes of administration, and patient teaching points. Organized for quick review and targeted studying, it aligns perfectly with HESI exam formats. Whether your program focuses on med-surg, pediatric, or psychiatric pharmacology, this guide gives you the confidence to tackle multiple-choice, application-based, and clinical scenario questions. Stop wasting time with scattered notes—this HESI Pharmacology Final Exam guide consolidates everything you need in one place. Designed for efficient, high-yield studying, it’s ideal for daily review, last-minute prep, or reinforcing complex drug concepts. Build your confidence, understand essential pharmacology principles, and maximize your score on the HESI Pharmacology Final Exam with this comprehensive, student-tested guide.

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Uploaded on
January 20, 2026
Number of pages
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Written in
2025/2026
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HESI PHARMACOLOGY FINAL
EXAM
1. What are the 5 rights of medication administration?

Answer Right Patient Right Drug

Right Route

Right Time

Right Dose

2. How do you safely prepare medication?

Answer Have good lighting & work alone.


Check medication label 3 times (When you grab the medication, Before dispensing medication, & When you replace

medication.)

Don't use anything without a label.


Bottles with bad labels need to be returned to the pharmacy.

Never transfer medication into another bottle.

Check expiration date.


,Inspect & throw away decomposing medications.


3. How would you administer medication via IM?

Answer Injecting at 90° using the Z-Track method.


4. How would you administer medication via IV?

Answer Assess for allergies. Assess the IV site for complications.

Clean the port closest to the IV site with alcohol swab.

Administer medication.

5. How would you administer medication via SubQ?

Answer Injecting 45° (Skinny Patient) or 90°


(Average Patient) into the fatty tissue.


6. How would you administer medication via oral route?

Answer Assist the patient into an upright or side lying position.

Ask patient if they would like the medications in his/her hand or in the cup.

Otter water.

Remain with the patient until each medication is swallowed. Never leave the patient's bedside.


,7. How would you instill ear medications?

Answer Warm the medication to prep it before entering the patient's room.

Clean any ear drainage.


Place the patient on his/her unattected side or have the patient sit up with head titled to the unattected side.

Straighten the ear canal by pulling up & back for adults or down & back for children.

Administer the medication and allow the drops to fall on the side of the canal. Avoid instilling in the middle of the canal

or the tympanic membrane.






, Instruct patient to remain in this position for 5 minutes.


Gently press on the tragus to facilitate the medication to travel towards the tympanic membrane.

If ordered loosely place a cotton ball into the ear canal.

If you have to administer drops in both ear wait 5 minutes between each side.


8. How would you instill eye medications?

Answer Otter the patient a tissue. Cleanse each eye from the inner area to

the outer area.

If the patient does not have cervical spine injury instruct the patient to tilt his/her head back.

Gently apply pressure with fingers at the edge of the lower eyelid to expose the conjunctival sac.

Administer the medication & release the lower eyelid.

Instruct patient to close eyes gently.


Apply gentle pressure on the inner canthus to prevent the medication from flowing into the tear ducts.

Instruct patient not to rub eyes.

9. How would you apply a transdermal patch?

Answer Wear gloves!
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