Wgu D115 Advanced Pathophysiology for the Advanced
Practice Nurse Objective Assessment - | Already Graded A |
Advanced Practice Competency
Which type of genetic disease affects males more frequently than females? - SELECTED
ANSWER 👀**** Sex-Linked recessive. Since males only have one X and one Y, if the
affected chromosome has the illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known cause? -
SELECTED ANSWER 👀**** Intellectual disability and fetal miscarriage. Chromosome
abnormalities are the leading known cause of intellectual disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - SELECTED ANSWER 👀****
Chorionic villus sampling (CVS), amniocentesis, and preimplantation genetic testing (PGT)
are examples of prenatal diagnostic studies and are performed in vitro. CVS is a form of
genetic testing that provides genetic information found in utero and is usually performed
between weeks 11 and 14 of pregnancy. An amniocentesis is a form of genetic testing that
evaluates amniotic fluid and is usually performed during the second trimester, between
weeks 15 and 20 of pregnancy. PGT is performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having one
chromosome with a normal complement of genes and one chromosome with a missing
gene? - SELECTED ANSWER 👀**** Cri du chat syndrome (translated as "cry of the cat")
is caused by a DNA deletion. This term describes the cry often heard from a baby affected
by the syndrome. Cri du chat syndrome can present as a microcephalic, low birth-weight
baby with a piercing cry.
How can an X-linked recessive disease skip generations? - SELECTED ANSWER 👀****
The disease can be transmitted through female carriers.
,Since females have two copies of the X chromosome, the mother may provide an
unaffected X to a daughter or son. Furthermore, a daughter may not show signs of the
disease because she has the other X (the only X the father can give to a female) to cancel it
out.
Which type of risk is referred to as the ratio of the disease rate among the entire population
to the disease rate in an unexposed population? - SELECTED ANSWER 👀**** Relative
risk is a ratio of probability, not an actual occurrence of disease.
What are the empirical risks for most multifactorial diseases based on? - SELECTED
ANSWER 👀**** Many factors from lifestyle to genetics affect multifactorial diseases.
Observation and evaluation of each case individually provides the most thorough and
accurate assessment.
What refers to the silenced gene of a gene pair. - SELECTED ANSWER 👀**** The
imprinted gene is the silent gene of a gene pair.
What is the primary reason that some older adults have impaired inflammation and wound
healing? - SELECTED ANSWER 👀**** The underlying chronic illness exists.
A generalized inflammatory response seen in chronic illness depletes the body's reserves to
fight against illness.
Which cells are the body's primary defense against parasite invasion? - SELECTED
ANSWER 👀**** Eosinophils are the body's primary defense against parasites.
What Phagocytes bacteria? - SELECTED ANSWER 👀**** Macrophages work by eating or
phagocytosing bacteria.
,What is the first response to a foreign pathogen? - SELECTED ANSWER 👀**** Helper T
cells
Which characteristic is the most important determinant of immunogenicity when considering
the antigen? - SELECTED ANSWER 👀**** Immunogenicity is primarily based on the ability
to recognize something foreign.
How are erythrocytes destroyed when mismatched blood is administered, causing an ABO
incompatibility? - SELECTED ANSWER 👀**** The complement pathway is activated in
response to blood incompatibility.
What is the hypersensitivity reaction that causes atopic dermatitis? - SELECTED ANSWER
👀**** An immediate (type I) hypersensitivity reaction causes atopic dermatitis.
Which four infections are considered fungal infections? - SELECTED ANSWER 👀****
Infection with a fungus is called mycosis and includes dermatophytes (e.g., tineas, which
refers to several skin mycoses, including ringworm and athlete's foot) and yeasts, which
include candida and aspergillus.
When is the earliest after sexual transmission of HIV that lab results can detect infection? -
SELECTED ANSWER 👀**** Lab testing can detect HIV RNA 4 to 10 days after sexual
transmission, whereas HIV antibody testing may take 23 to 90 days to result in a positive
test. Repeat testing may be needed to rule out a false negative test due to testing too soon
after exposure, especially if a high likelihood of exposure is suspected.
What is a characteristic of exotoxins? - SELECTED ANSWER 👀**** Exotoxins are
released during bacterial growth.
, Which dietary lifestyle choice has been associated with a decreased risk for developing
colon cancer? - SELECTED ANSWER 👀**** The results of decreased fat consumption
have been widely studied and have demonstrated a decreased risk of developing colon
cancer.
Which cancer is an individual who has worked with asbestos for over 40 years most likely to
develop? - SELECTED ANSWER 👀**** Asbestos exposure results in an increased risk of
lung and lung lining cancer.
Which statement is true regarding ultraviolet (UV) light?
The degree of damage is not affected by the light's wavelength. - SELECTED ANSWER
👀**** UV light causes basal cell carcinoma and squamous cell carcinoma when the UVB
rays hit DNA strands, causing thymine base pairs that are side by side to pair together,
becoming thymine dimers. These thymine dimers lead to cell death or cancer.
Which cancer does exercise have a convincing impact on reducing? - SELECTED
ANSWER 👀**** Exercise-induced myokines cause apoptosis of colon cancer cells.
Low healthcare literacy is recognized as a major risk factor in blood pressure control and
has been shown to have adverse effects on health outcomes.
true or false - SELECTED ANSWER 👀**** TRUE
By providing patient education at the appropriate literacy level, improved health outcomes
may result.
One of the goals of the National Action Plan to Improve Health Literacy is to incorporate
research and evidence-based plans of treatment from childhood through university-level
education in a manner consistent with an individual's literacy level.
True or false - SELECTED ANSWER 👀**** True
Practice Nurse Objective Assessment - | Already Graded A |
Advanced Practice Competency
Which type of genetic disease affects males more frequently than females? - SELECTED
ANSWER 👀**** Sex-Linked recessive. Since males only have one X and one Y, if the
affected chromosome has the illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known cause? -
SELECTED ANSWER 👀**** Intellectual disability and fetal miscarriage. Chromosome
abnormalities are the leading known cause of intellectual disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - SELECTED ANSWER 👀****
Chorionic villus sampling (CVS), amniocentesis, and preimplantation genetic testing (PGT)
are examples of prenatal diagnostic studies and are performed in vitro. CVS is a form of
genetic testing that provides genetic information found in utero and is usually performed
between weeks 11 and 14 of pregnancy. An amniocentesis is a form of genetic testing that
evaluates amniotic fluid and is usually performed during the second trimester, between
weeks 15 and 20 of pregnancy. PGT is performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having one
chromosome with a normal complement of genes and one chromosome with a missing
gene? - SELECTED ANSWER 👀**** Cri du chat syndrome (translated as "cry of the cat")
is caused by a DNA deletion. This term describes the cry often heard from a baby affected
by the syndrome. Cri du chat syndrome can present as a microcephalic, low birth-weight
baby with a piercing cry.
How can an X-linked recessive disease skip generations? - SELECTED ANSWER 👀****
The disease can be transmitted through female carriers.
,Since females have two copies of the X chromosome, the mother may provide an
unaffected X to a daughter or son. Furthermore, a daughter may not show signs of the
disease because she has the other X (the only X the father can give to a female) to cancel it
out.
Which type of risk is referred to as the ratio of the disease rate among the entire population
to the disease rate in an unexposed population? - SELECTED ANSWER 👀**** Relative
risk is a ratio of probability, not an actual occurrence of disease.
What are the empirical risks for most multifactorial diseases based on? - SELECTED
ANSWER 👀**** Many factors from lifestyle to genetics affect multifactorial diseases.
Observation and evaluation of each case individually provides the most thorough and
accurate assessment.
What refers to the silenced gene of a gene pair. - SELECTED ANSWER 👀**** The
imprinted gene is the silent gene of a gene pair.
What is the primary reason that some older adults have impaired inflammation and wound
healing? - SELECTED ANSWER 👀**** The underlying chronic illness exists.
A generalized inflammatory response seen in chronic illness depletes the body's reserves to
fight against illness.
Which cells are the body's primary defense against parasite invasion? - SELECTED
ANSWER 👀**** Eosinophils are the body's primary defense against parasites.
What Phagocytes bacteria? - SELECTED ANSWER 👀**** Macrophages work by eating or
phagocytosing bacteria.
,What is the first response to a foreign pathogen? - SELECTED ANSWER 👀**** Helper T
cells
Which characteristic is the most important determinant of immunogenicity when considering
the antigen? - SELECTED ANSWER 👀**** Immunogenicity is primarily based on the ability
to recognize something foreign.
How are erythrocytes destroyed when mismatched blood is administered, causing an ABO
incompatibility? - SELECTED ANSWER 👀**** The complement pathway is activated in
response to blood incompatibility.
What is the hypersensitivity reaction that causes atopic dermatitis? - SELECTED ANSWER
👀**** An immediate (type I) hypersensitivity reaction causes atopic dermatitis.
Which four infections are considered fungal infections? - SELECTED ANSWER 👀****
Infection with a fungus is called mycosis and includes dermatophytes (e.g., tineas, which
refers to several skin mycoses, including ringworm and athlete's foot) and yeasts, which
include candida and aspergillus.
When is the earliest after sexual transmission of HIV that lab results can detect infection? -
SELECTED ANSWER 👀**** Lab testing can detect HIV RNA 4 to 10 days after sexual
transmission, whereas HIV antibody testing may take 23 to 90 days to result in a positive
test. Repeat testing may be needed to rule out a false negative test due to testing too soon
after exposure, especially if a high likelihood of exposure is suspected.
What is a characteristic of exotoxins? - SELECTED ANSWER 👀**** Exotoxins are
released during bacterial growth.
, Which dietary lifestyle choice has been associated with a decreased risk for developing
colon cancer? - SELECTED ANSWER 👀**** The results of decreased fat consumption
have been widely studied and have demonstrated a decreased risk of developing colon
cancer.
Which cancer is an individual who has worked with asbestos for over 40 years most likely to
develop? - SELECTED ANSWER 👀**** Asbestos exposure results in an increased risk of
lung and lung lining cancer.
Which statement is true regarding ultraviolet (UV) light?
The degree of damage is not affected by the light's wavelength. - SELECTED ANSWER
👀**** UV light causes basal cell carcinoma and squamous cell carcinoma when the UVB
rays hit DNA strands, causing thymine base pairs that are side by side to pair together,
becoming thymine dimers. These thymine dimers lead to cell death or cancer.
Which cancer does exercise have a convincing impact on reducing? - SELECTED
ANSWER 👀**** Exercise-induced myokines cause apoptosis of colon cancer cells.
Low healthcare literacy is recognized as a major risk factor in blood pressure control and
has been shown to have adverse effects on health outcomes.
true or false - SELECTED ANSWER 👀**** TRUE
By providing patient education at the appropriate literacy level, improved health outcomes
may result.
One of the goals of the National Action Plan to Improve Health Literacy is to incorporate
research and evidence-based plans of treatment from childhood through university-level
education in a manner consistent with an individual's literacy level.
True or false - SELECTED ANSWER 👀**** True
