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MCAT Biology Practice Questions – Verified Answers | 100% Latest Update 2026 | Exam-Focused

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This MCAT Biology Practice Questions resource provides a comprehensive set of verified, exam-style questions, fully updated for 2026. Perfect for pre-medical students preparing for the MCAT, it covers high-yield topics in molecular and cell biology, genetics, microbiology, physiology, biochemistry, reproduction, development, and systems biology.

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Uploaded on
January 18, 2026
Number of pages
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Written in
2025/2026
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MCAT Biology Practice Questions – Verified
Answers | 100% Latest Update 2026 | Exam-
Focused




Hyperbaric oxygen may be used as a treatment for certain types of
bacterial infections. In this therapy, the patient is placed in a which
the partial pressure of oxygen is significantly increased, increasing
the partial pressure of oxygen in the patient's tissues. This treatment
is most likely used for infections with:

A. obligate aerobic bacteria
B. facultative anaerobix bacteria
C. aerotolerant anarobic bacteria
D. obligate anaerobic bacteria - CORRECT ANSWER✔✔D

Which of the following does NOT describe connective tissue cells?

A.They account for most cells in muscles, bones, and tendons
B.They secrete substances to form the extracellular matrix
C.in organs, they tend to form the stroma
D.In organs, they provide support for epithelial cells - CORRECT
ANSWER✔✔A

Which of the following types of nucleic acid could form the genome of
a virus?
I. Single-stranded RNA
II. Double-stranded RNA
III. Single-stranded DNA



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A. I only
B. II only
C. I and II only
D I, II and III - CORRECT ANSWER✔✔D

Which of the following activities occurs in the Golgi apparatus?

A. Synthesis of proteins
B. Modification and distribution of proteins
C. Breakdown of lipids and carbohydrates
D. Production of ATP - CORRECT ANSWER✔✔B

Mitochondrial DNA is:
I. circular
II. self-replicating
III. single-stranded

A. I only
B. II only
C. I and II only
D. I, II and III - CORRECT ANSWER✔✔C

Which of the following is NOT a function of the smooth endoplasmic
reticulum?

A. Lipid synthesis
B. Poison detoxification
C. Protein synthesis
D. Transport of proteins - CORRECT ANSWER✔✔C

What is the main function of the nucleolus?

A. Ribosomal RNA synthesis
B. DNA replication
C. Cell division
D. Chromosome assembly - CORRECT ANSWER✔✔A

Which of the following organelles is surrounded by a single membrane?


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A. Lysosomes
B. Mitochondria
C. Nuclei
D. Ribosomes - CORRECT ANSWER✔✔A

Which of the following is NOT a difference that would allow one to
distinguish a prokaryotic and a eukaryotic cell?

A. Ribosomal subunit weight
B. Presence of a nucleus
C. Presence of a membrane on the outside surface of the cell
D. Presence of membrane-bound organelles - CORRECT ANSWER✔✔C

Which of the following does NOT contain tubulin?

A. Cilia
B. Flagella
C. Microfilaments
D. Centrioles - CORRECT ANSWER✔✔C

Herpes simplex virus (HSV) enters the human body and remains
dormant in the nervous system until is produces an outbreak after
exposure to heat, radiation, or other stimuli. Which of the following
statements correctly describes HSV?

A. While it remains dormant in the nervous system, the virus is in its
lytic cycle
B. During an outbreak the virus is in the lysogenic cycle
C. Herpes simplex virus adds it genetic information to the genetic
information of the cell
D. The herpes simplex virus contains a tail sheath and tail fibers -
CORRECT ANSWER✔✔C

Resistance to antibiotics is a well-recognized medical problem. Which
mechanism(s) can account for a bacterium's ability to increase its
genetic variability and thus adapt itself to resist different antibiotics?
I. Binary Fission


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II. Conjugation
III. Transduction

A. I and II only
B. I and III only
C. II and III only
D. I, II and III - CORRECT ANSWER✔✔C

A bacterial cell is noted to be resistant to penicillin. The bacterium is
transferred to a colony that lacks the fertility factor, and the rest of
the colony does not become resistant to penicillin. However, the
penicillin-resistant cell has started to exhibit other phenotypic
characteristics, including secretion of a novel protein. Which of the
following methods of bacterial recombination is NOT likely to account
for this change?

A. Conjugation
B. Transformation
C. Transduction
D. Infection with a bacteriophage - CORRECT ANSWER✔✔A

In Alzheimers disease, a protein called the amyloid precursor protein
(APP) is cleaved to form a protein called B-amyloid. This protein has a
B-pleated sheet structure and precipitates to form plaques in the
brain. This mechanism of disease is most similar to which of the
following pathogens?

A. Bacteria
B. Viruses
C. Prions
D. Viroids - CORRECT ANSWER✔✔C

Which of the following is the correct sequence of the development of a
mature sperm cell?

A. Spermatid -> spermatocyte -> spermatogonium -> 2 degree
spermatocyte -> spermatozoan



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