DNA Replication Quiz (50+ Q&A) – BIO 2026 – Nucleotides, Enzymes, RNA Types, Base Pairing, Replication Process

This fully answered quiz provides over 50 exam-level questions covering the complete topic of DNA replication for BIO 2026 students. It begins with foundational concepts such as the discovery of DNA (Watson, Crick, Wilkins, and Rosalind Franklin’s contributions), and progresses through nucleotide structure, base-pairing rules, DNA/RNA differences, Chargaff’s Rule, and forms of DNA (A, B, Z). The resource details the entire replication process, including the roles of critical enzymes like helicase, primase, DNA polymerase I and III, ligase, and topoisomerase, along with Okazaki fragments and directionality of strand synthesis. It also emphasizes the importance of anti-parallel DNA structure, replication timing (S phase), and location (nucleus). Students are introduced to the differences between prokaryotic and eukaryotic replication duration, the types and functions of RNA (mRNA, rRNA, tRNA), and proper strand orientation (5’ to 3’). This document is ideal for: High school and college students enrolled in introductory Biology or Genetics Pre-med or health science students preparing for molecular biology exams Teachers and tutors seeking a ready-made, high-quality review sheet Students preparing for standardized science tests such as AP Biology Keywords: DNA replication, RNA types, nucleotide structure, DNA enzymes, base pairing, helicase, DNA polymerase, ligase, S phase, Okazaki fragments, anti-parallel DNA, BIO 2026, replication direction, Chargaff’s Rule, double helix, replication quiz