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NSG233 Medical Surgical Nursing III Exam 3 Study Guide & Practice Questions - Herzing University | 2026/2027 Mastery Update

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Achieve mastery in Herzing University's NSG233 Medical Surgical Nursing III with this comprehensive Exam 3 study guide, updated for the 2026/2027 curriculum. This essential Grade A resource covers critical care topics, complex patient management, and advanced pathophysiology. Prepare with detailed concept reviews, practice questions, and priority-setting scenarios that reflect the exam format. Perfect for mastering advanced med-surg concepts and building confidence for both your final exam and future NCLEX-RN success.

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NSG233 Medical Surgical Nursing III Exam 3 Study
Guide & Practice Questions - Herzing University |
2026/2027 Mastery Update

Exam Profile

Questions: 65 | Time: 90 min

Focus: Advanced Clinical Judgment, Multi-System Failure, High-Acuity Prioritization

Formats: Unfolding Case Studies, SATA, Complex Multiple Choice, Calculations



CLUSTER 1 – Cardio-Respiratory-Renal Integration (15 Questions)

Case Study 1 – Questions 1-4

A 68-year-old with ischemic cardiomyopathy (EF 25 %) is admitted with acute dyspnea,
bilateral crackles, +3 pitting edema. ABG on 4 L NC: pH 7.28, PaCO₂ 55 mmHg, PaO₂ 68
mmHg, HCO₃ 24 mEq/L.

Q1 The nurse’s primary interpretation is:

A. Acute pulmonary embolism

B. Acute respiratory acidosis due to COPD exacerbation

C. Cardiogenic pulmonary edema leading to hypoxemia and respiratory acidosis

D. Metabolic acidosis with respiratory compensation

Verified Answer: C

,Rationale: Low EF + crackles/edema + acute ↑PaCO₂/low pO₂ = flash pulmonary edema;
normal HCO₃ rules out chronic process.



Q2 (Follow-up) Provider orders: furosemide 80 mg IV STAT, nitroglycerin 10 mcg/min IV.
Most critical assessment within 1 hour?

A. Monitor for hypokalemia

B. Frequent BP & respiratory rate assessment

C. Check for ototoxicity

D. Assess urine output q4 h

Verified Answer: B

Rationale: High-dose diuretic + vasodilator in hypotension-prone patient mandates
continuous hemodynamic monitoring; prevents cardiogenic shock.



Q3 (SATA) After 2 h on BiPAP (IPAP 12, EPAP 5) ABG: pH 7.22, PaCO₂ 75, PaO₂ 70.
Which actions are immediately appropriate? (Select ALL)

A. Call anesthesia for urgent intubation

B. Increase IPAP to 16 cm H₂O

C. Obtain ABG in 30 min

D. Start norepinephrine for MAP <65 mmHg

E. Give bicarbonate 1 amp IV

Verified Answers: A, B, C, D

,Rationale: Worsening hypercapnic acidosis = NIV failure; prepare for intubation (A),
optimize settings (B), monitor (C), support perfusion (D). Bicarb (E) not indicated.



Q4 (Calc) Loading dose aminophylline 6 mg/kg IV over 30 min; concentration 500
mg/250 mL. Client weight 65 kg.

a) Volume = ______ mL b) Pump rate = ______ mL/hr

Answers: a) 19.5 mL b) 39 mL/hr

Rationale: 6 × 65 = 390 mg; 500 mg/250 mL = 2 mg/mL → 390 ÷ 2 = 19.5 mL. Over 30
min → 19.5 × 2 = 39 mL/hr.



Q5 Stroke client NIHSS 14, last known normal 90 min ago, CT negative. Next priority?

A. Start heparin drip

B. Administer tPA 0.9 mg/kg IV per protocol

C. Obtain MRI

D. Lower BP to <140/90

Verified Answer: B

Rationale: <4.5 h window + eligible NIHSS → tPA is time-sensitive priority (AHA 2025).
Heparin (A) not acute therapy.



Q6 (SATA) Client with STEMI on tPA; sudden headache, NIHSS ↑ by 4, BP 190/100.
Immediate actions? (Select ALL)

A. Stop tPA infusion immediately

, B. Obtain non-contrast CT within 1 h

C. Prepare blood products (6 U PRBC, FFP, platelets)

D. Lower BP with labetalol to <185/110

E. Give mannitol 1 g/kg IV

Verified Answers: A, B, C, D

Rationale: Suspected ICH: stop thrombolytic (A), urgent imaging (B), blood products
ready (C), control HTT (D). Mannitol (E) after neurosurgical consult.



Q7 Client on mechanical ventilation (VC-AC) has peak airway pressure ↑ from 25 to 45
cm H₂O; plateau unchanged. Problem?

A. Airway obstruction or secretions

B. Tension pneumothorax

C. ARDS development

D. Abdominal distension

Verified Answer: A

Rationale: ↑ peak with normal plateau = increased airway resistance (secretions, kink,
bronchospasm). Plateau ↑ = compliance issue (B, C, D).



Q8 (Prioritization) Four post-MI clients on telemetry. Who needs immediate
assessment?

A. Sinus bradycardia 48 bpm, BP 100/60, no symptoms
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