ENDOCRINE PRACTICE PAPER 2026
COMPLETE SOLUTIONS
◉ What is the primary function of cortisol? Answer: It is released
during times of stress, suppresses the inflammatory response, and
increases blood glucose.
◉ What condition is caused by excessive cortisol? Answer: Cushing
Syndrome
◉ What are common risk factors for Cushing Syndrome? Answer:
Excess corticosteroid administration, pituitary or adrenal tumors.
◉ What are the common physical assessments for Cushing
Syndrome? Answer: Moon face, truncal obesity, buffalo hump, striae,
thin skin.
◉ What are the electrolyte imbalances associated with Cushing
Syndrome? Answer: Hypervolemia and hypokalemia.
◉ What is Addison's Disease? Answer: A condition of too little
cortisol.
, ◉ What are the risk factors for Addison's Disease? Answer:
Autoimmune disorders of adrenal glands, adults under 60.
◉ What are the symptoms of Addison's Disease? Answer: Anorexia,
nausea, progressive weakness, fatigue, weight loss, bronze
hyperpigmentation.
◉ What is SIADH? Answer: Syndrome of Inappropriate ADH,
characterized by excessive release of ADH.
◉ What are the common causes of SIADH? Answer: Cancer, head
injury, CNS disorders.
◉ What are the symptoms of SIADH? Answer: Neurological changes,
low urine output, seizures, nausea, edema.
◉ What is Diabetes Insipidus? Answer: A condition of insufficient
ADH leading to excessive thirst and polyuria.
◉ What are the risk factors for Diabetes Insipidus? Answer:
Genetics, kidney disorders, CNS disorders, brain tumors, lithium
therapy.