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When histamine binds to the H1 receptor, the receptor undergoes a _____
change and binds the _____. - 🧠 ANSWER ✔✔conformation
inactive G protein
Unlike steroid hormones, ______ that are large and/or hydrophilic cannot
pass through the cell's plasma membrane and therefore must bind _____
to receptor molecules in the plasma membrane. - 🧠 ANSWER ✔✔signaling
molecules
extracellularly
, Which of the following provides molecular evidence that signal transduction
pathways evolved early in the history of life? - 🧠 ANSWER ✔✔The
molecular details of cell signaling are quite similar in organisms whose last
common ancestor was a billion years ago.
Which of the following is a substance that acts at a long distance from the
site at which it is secreted? - 🧠 ANSWER ✔✔hormone
To what does the term "ligand" refer in cell biology? - 🧠 ANSWER ✔✔any
small molecule that can bind in a specific manner to a larger one
Dioxin, produced as a by-product of various industrial chemical processes,
is suspected of contributing to the development of cancer and birth defects
in animals and humans. It apparently acts by entering cells by simple
diffusion and binding to proteins in the cytoplasm, then altering the pattern
of gene expression. Which of the following are likely to be the cytoplasmic
proteins to which dioxin binds? - 🧠 ANSWER ✔✔transcription factors
Steroid hormone receptors located in the cytoplasm could be bound by
______, just as they are bound by the steroids that diffuse into the cell.
Once bound by the dioxins, the cytoplasmic receptor/dioxin complexes