ANCC AGACNP Barkley Review verified questions and answers!
What is the normal hemoglobin range for males? 14-18 g/100 mL
What is the normal hemoglobin range for 12-16 g/100 mL
females?
What does hematocrit (Hct) measure? The percentage of a given volume of whole blood that is occupied by
erythrocytes.
What is the normal hematocrit range for females? 37-47%
What is the normal hematocrit range for males? 40-54%
What does an increased Total Iron Binding Iron deficiency
Capacity (TIBC) indicate?
What does a decreased Total Iron Binding Anemia, hemorrhage, or hemolysis
Capacity (TIBC) indicate?
What is the normal range for Total Iron Binding 250-450 mcg/dL
Capacity (TIBC)?
Serum iron Normal: 50-150 ug/dL
Page 1 of 174
,ANCC AGACNP Barkley Review verified questions and answers!
Mean Corpuscular Volume (MCV) Expression of the average volume and size of individual erythrocytes.
Normal: 80-100 um3
Microcytic = < 80, Normocytic = 80-100, and Macrocytic = > 100.
Mean Corpuscular Hemoglobin (MCH) Expression of the average amount and weight of Hgb contained in a
single erythrocyte.
Normal: 26-34 pg
Mean Corpuscular Hemoglobin Concentration Expression of the average Hgb concentration or proportion of each
(MCHC) RBC occupied by Hgb as a percentage; more accurate measure than
MCH.
Normal: 32-36%
Hypochromic < 32%, normochromic 32-36%, hyperchromic > 36%
Differential for low mean corpuscular volume Iron deficiency anemia and thalassemia.
(MCV)
Differential for high mean corpuscular volume B12 or folate deficiency (Megaloblastic anemia), alcoholism, liver
(MCV) failure, and drug effects.
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,ANCC AGACNP Barkley Review verified questions and answers!
Differential for normal mean corpuscular volume Anemia of chronic disease, sickle cell, renal failure, blood loss, and
(MCV) hemolysis.
Iron deficiency anemia is what type if anemia? Microcytic, Hypochromic.
Iron deficiency anemia A microcytic-hypochromic type of anemia characterized by iron
deficiency that affects the production of hemoglobin and is
characterized by small red blood cells containing low amounts of
hemoglobin.
Signs and symptoms of iron deficiency anemia Usually few symptoms if Hct is greater than 30. As Hct decreases,
symptoms present: pica, dyspnea and mild fatigue with exercise, HA,
palpitations, weakness, tachycardia, postural hypotension, and pallor.
Laboratory findings in iron deficiency anemia Low Hgb, low Hct, low MCV, low MCHC, low RBC, low serum iron, low
serum ferritin (iron storage), high TIBC , *high RDW (red cell
distribution width.
*Indicates there is a large difference in size from the largest to smallest
RBC.
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, ANCC AGACNP Barkley Review verified questions and answers!
How is iron deficiency anemia treated Ferrous sulfate orally 300-325 mg 1-3 hour after meals. Do not take
iron supplements with antacids, it can interfere with absorption. Take
with vitamin C containing juices.
Increase iron intake: Raisins, green leafy vegetables, red meats, citrus
products, and iron-fortified bread and cereals.
What type of anemia is thalassemia Microcytic, hypochromic.
Thalassemia Genetic inherited disorders resulting in abnormal Hgb production and
microcytic, hypochromic anemia. Mostly found in Mediterranean,
African American, Middle Eastern, Indian, and Asian populations.
Etiology of thalassemia There is a decreased production of adult hemoglobin (Hb A); The
global part of Hb A has 4 protein sections called polypeptide chains -
(1) two of these chains are called alpha chains and are identical, (2) the
other two are identical but different from the alpha chains, called beta
chains.
What is the most common type of thalassemia Beta thalassemia
What is the cause of beta thalassemia There is a reduction or absent production of beta globin chains.
Page 4 of 174
What is the normal hemoglobin range for males? 14-18 g/100 mL
What is the normal hemoglobin range for 12-16 g/100 mL
females?
What does hematocrit (Hct) measure? The percentage of a given volume of whole blood that is occupied by
erythrocytes.
What is the normal hematocrit range for females? 37-47%
What is the normal hematocrit range for males? 40-54%
What does an increased Total Iron Binding Iron deficiency
Capacity (TIBC) indicate?
What does a decreased Total Iron Binding Anemia, hemorrhage, or hemolysis
Capacity (TIBC) indicate?
What is the normal range for Total Iron Binding 250-450 mcg/dL
Capacity (TIBC)?
Serum iron Normal: 50-150 ug/dL
Page 1 of 174
,ANCC AGACNP Barkley Review verified questions and answers!
Mean Corpuscular Volume (MCV) Expression of the average volume and size of individual erythrocytes.
Normal: 80-100 um3
Microcytic = < 80, Normocytic = 80-100, and Macrocytic = > 100.
Mean Corpuscular Hemoglobin (MCH) Expression of the average amount and weight of Hgb contained in a
single erythrocyte.
Normal: 26-34 pg
Mean Corpuscular Hemoglobin Concentration Expression of the average Hgb concentration or proportion of each
(MCHC) RBC occupied by Hgb as a percentage; more accurate measure than
MCH.
Normal: 32-36%
Hypochromic < 32%, normochromic 32-36%, hyperchromic > 36%
Differential for low mean corpuscular volume Iron deficiency anemia and thalassemia.
(MCV)
Differential for high mean corpuscular volume B12 or folate deficiency (Megaloblastic anemia), alcoholism, liver
(MCV) failure, and drug effects.
Page 2 of 174
,ANCC AGACNP Barkley Review verified questions and answers!
Differential for normal mean corpuscular volume Anemia of chronic disease, sickle cell, renal failure, blood loss, and
(MCV) hemolysis.
Iron deficiency anemia is what type if anemia? Microcytic, Hypochromic.
Iron deficiency anemia A microcytic-hypochromic type of anemia characterized by iron
deficiency that affects the production of hemoglobin and is
characterized by small red blood cells containing low amounts of
hemoglobin.
Signs and symptoms of iron deficiency anemia Usually few symptoms if Hct is greater than 30. As Hct decreases,
symptoms present: pica, dyspnea and mild fatigue with exercise, HA,
palpitations, weakness, tachycardia, postural hypotension, and pallor.
Laboratory findings in iron deficiency anemia Low Hgb, low Hct, low MCV, low MCHC, low RBC, low serum iron, low
serum ferritin (iron storage), high TIBC , *high RDW (red cell
distribution width.
*Indicates there is a large difference in size from the largest to smallest
RBC.
Page 3 of 174
, ANCC AGACNP Barkley Review verified questions and answers!
How is iron deficiency anemia treated Ferrous sulfate orally 300-325 mg 1-3 hour after meals. Do not take
iron supplements with antacids, it can interfere with absorption. Take
with vitamin C containing juices.
Increase iron intake: Raisins, green leafy vegetables, red meats, citrus
products, and iron-fortified bread and cereals.
What type of anemia is thalassemia Microcytic, hypochromic.
Thalassemia Genetic inherited disorders resulting in abnormal Hgb production and
microcytic, hypochromic anemia. Mostly found in Mediterranean,
African American, Middle Eastern, Indian, and Asian populations.
Etiology of thalassemia There is a decreased production of adult hemoglobin (Hb A); The
global part of Hb A has 4 protein sections called polypeptide chains -
(1) two of these chains are called alpha chains and are identical, (2) the
other two are identical but different from the alpha chains, called beta
chains.
What is the most common type of thalassemia Beta thalassemia
What is the cause of beta thalassemia There is a reduction or absent production of beta globin chains.
Page 4 of 174
