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ANCC FNP Exam 2026/2027 – All Current
Real Exam Questions with Accurate Verified
Answers | Guaranteed Pass | Grade A
Subject: Family Nurse Practitioner (ANCC Exam)
Source: ANCC FNP Exam 2026/2027 Study Questions
Format: Q&A with Rationale
1. What causes anaphylaxis and what is the treatment?
A. IgM-mediated reaction; treat with IV fluids only
B. IgE-mediated reaction; treat with epinephrine 0.3-0.5 mg
C. IgG-mediated reaction; treat with steroids first
D. T-cell-mediated reaction; treat with antihistamines only
Correct Answer: B
Rationale:
1. Anaphylaxis is a severe, acute-onset IgE-mediated hypersensitivity
reaction.
2. Common triggers include foods, drugs, and insect stings.
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3. First-line treatment is intramuscular epinephrine (0.3–0.5 mg) to
reverse bronchoconstriction and hypotension.
2. Rocky Mountain spotted fever diagnosis and treatment:
A. Fever and rash on trunk; treat with amoxicillin; diagnose with rapid
antigen test
B. Fever, arthralgia, rash on wrists/forearms; treat with doxycycline;
diagnose with antibody titers
C. Cough and conjunctivitis; treat with ceftriaxone; diagnose with chest X-
ray
D. Headache and photophobia; treat with azithromycin; diagnose with CSF
culture
Correct Answer: B
Rationale:
1. RMSF presents with abrupt fever, headache, arthralgia, and a red
spotted rash starting on wrists/forearms.
2. Doxycycline is first-line treatment (safe in children).
3. Diagnosis is confirmed by paired antibody titers to R. rickettsii.
3. A pathognomonic sign of measles is:
A. Strawberry tongue
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B. Koplik's spots
C. Rose spots
D. Petechiae
Correct Answer: B
Rationale:
1. Koplik's spots are small white lesions on a red base on the buccal
mucosa.
2. They appear 2–3 days before the onset of the measles rash.
3. Their presence is diagnostic for measles.
4. Which finding is characteristic of meningococcemia?
A. Painful purple to dark red skin lesions with fever
B. Rash starting on palms and soles only
C. Non-blanching petechiae on trunk
D. Vesicular rash on dermatomes
Correct Answer: A
Rationale:
1. Meningococcemia causes painful purpuric skin lesions accompanied
by high fever.
2. It is a medical emergency requiring immediate antibiotics.
3. Close contacts require rifampin prophylaxis.
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5. A brown recluse spider bite typically presents as:
A. Large painless ulcer immediately after bite
B. Swollen tender blister within 24 hours with purple/black center
C. Linear streaking with lymph node enlargement
D. Multiple vesicles in a cluster
Correct Answer: B
Rationale:
1. Brown recluse bites cause a tender blister within 24 hours.
2. The lesion progresses to central necrosis with purple/black
discoloration.
3. Management includes wound care, analgesia, and monitoring for
systemic symptoms.
6. Most common melanoma in African Americans and Asians:
A. Nodular melanoma
B. Lentigo maligna melanoma
C. Acral lentiginous melanoma
D. Amelanotic melanoma
Correct Answer: C
Rationale:
ANCC FNP Exam 2026/2027 – All Current
Real Exam Questions with Accurate Verified
Answers | Guaranteed Pass | Grade A
Subject: Family Nurse Practitioner (ANCC Exam)
Source: ANCC FNP Exam 2026/2027 Study Questions
Format: Q&A with Rationale
1. What causes anaphylaxis and what is the treatment?
A. IgM-mediated reaction; treat with IV fluids only
B. IgE-mediated reaction; treat with epinephrine 0.3-0.5 mg
C. IgG-mediated reaction; treat with steroids first
D. T-cell-mediated reaction; treat with antihistamines only
Correct Answer: B
Rationale:
1. Anaphylaxis is a severe, acute-onset IgE-mediated hypersensitivity
reaction.
2. Common triggers include foods, drugs, and insect stings.
, 2|Page
3. First-line treatment is intramuscular epinephrine (0.3–0.5 mg) to
reverse bronchoconstriction and hypotension.
2. Rocky Mountain spotted fever diagnosis and treatment:
A. Fever and rash on trunk; treat with amoxicillin; diagnose with rapid
antigen test
B. Fever, arthralgia, rash on wrists/forearms; treat with doxycycline;
diagnose with antibody titers
C. Cough and conjunctivitis; treat with ceftriaxone; diagnose with chest X-
ray
D. Headache and photophobia; treat with azithromycin; diagnose with CSF
culture
Correct Answer: B
Rationale:
1. RMSF presents with abrupt fever, headache, arthralgia, and a red
spotted rash starting on wrists/forearms.
2. Doxycycline is first-line treatment (safe in children).
3. Diagnosis is confirmed by paired antibody titers to R. rickettsii.
3. A pathognomonic sign of measles is:
A. Strawberry tongue
, 3|Page
B. Koplik's spots
C. Rose spots
D. Petechiae
Correct Answer: B
Rationale:
1. Koplik's spots are small white lesions on a red base on the buccal
mucosa.
2. They appear 2–3 days before the onset of the measles rash.
3. Their presence is diagnostic for measles.
4. Which finding is characteristic of meningococcemia?
A. Painful purple to dark red skin lesions with fever
B. Rash starting on palms and soles only
C. Non-blanching petechiae on trunk
D. Vesicular rash on dermatomes
Correct Answer: A
Rationale:
1. Meningococcemia causes painful purpuric skin lesions accompanied
by high fever.
2. It is a medical emergency requiring immediate antibiotics.
3. Close contacts require rifampin prophylaxis.
, 4|Page
5. A brown recluse spider bite typically presents as:
A. Large painless ulcer immediately after bite
B. Swollen tender blister within 24 hours with purple/black center
C. Linear streaking with lymph node enlargement
D. Multiple vesicles in a cluster
Correct Answer: B
Rationale:
1. Brown recluse bites cause a tender blister within 24 hours.
2. The lesion progresses to central necrosis with purple/black
discoloration.
3. Management includes wound care, analgesia, and monitoring for
systemic symptoms.
6. Most common melanoma in African Americans and Asians:
A. Nodular melanoma
B. Lentigo maligna melanoma
C. Acral lentiginous melanoma
D. Amelanotic melanoma
Correct Answer: C
Rationale:
