CPJE CLINICAL EXAMINATION TEST 2026
QUESTIONS AND ANSWERS VERIFIED 100%
CORRECT
◉ HLA b1502. Answer: Test in Asians. Rash for carbamazepine
(tegretol), phenytoin (Dilantin), fos phenytoin (cerebyx)
◉ Trastuzumab. Answer: Herceptin, her/Neu- ado-trastuzunab
(kadcyla), lapatinib (tykerb) pertuzumab (perjeta)
◉ Hla- b 5701. Answer: Don't give abacavir (ziagen), epzicom,
trizivir
◉ Not cross reactive a/ opioid allergy. Answer: Fentanyl, meperidine
(Demerol), methadone (dolophine), tramadol (ultram), tapentadol
(nucynta)
◉ Inducers. Answer: Ps porcs (phenytoin, smoking, phenobarbital,
oxcarbazepine, rifampin, carbamazepine, St. John's wort)
◉ Inhibitors. Answer: Gpacman (grapefruit, pi's, azoles,
cimetidine/cyclosporine, macrolides- erytho/clarithro, amiodarone,
non dihydro (dilt, verapamil)
,◉ If on amiodarone, decrease these drugs by 30-50%. Answer:
Digoxin, warfarin, quinidine, procainanide, statins
◉ Statins with high risk of inhibition. Answer: Las (lova, atorva,
simva)
◉ Entecavir. Answer: Baraclude. Empty stomach for hep B that fail
lamivudime and adefovir- se: peripheral edema, nephrotoxic
◉ Ribavirin. Answer: Copegus. W/ food bid for hep c, hepatotoxic,
hemolytic anemia, preg x, psych disorders, ci: renal disfxn
◉ Glipizide. Answer: Glucotrol 30 min before break & dinner
◉ Glimeprimide. Answer: Amaryl 1-2 mg qd w/ 1st meal
◉ Glyburide. Answer: Diabeta, + metformin = glucovance, do not use
w/ renal failure 2.5-5mg qd
◉ Rosiglitazone. Answer: Avandia 4-8mg qd (tzd, exacerbate hf, liver
damage, increases hdl, decreases tg/total cholesterol) similar:
pioglitazone (actos)
, ◉ Repaglinide. Answer: Prandin 0.5-2mg TID 15-30 min before a
meal, hypoglycemia- do not take with su's
◉ Nateglinide. Answer: Starlix injection- 15-30 min before meals
◉ Acarbose. Answer: Precose- w/ 1st bite of meal and water
◉ Miglitol. Answer: Glyset w/ 1st bite of meal and water
◉ Linagliptan. Answer: Tradjenta- 5 mg qd in morning with or
without food, no renal adjustment
◉ Saxagliptin. Answer: OnglyZa 2.5-5mg qd
◉ Canaglifozin. Answer: Invokana 100mg qd before first meal of day
for DM. Se: female genital mycotic infxn, increased urination,
hyperkalemia, can increase dig levels, ci: renal dx
◉ Exenatide. Answer: Byetta 30-60 min before am & pm
meals,medguide, pancreatitis, thyroid c-cell carcinoma xr= bydureon
◉ Liraglutide. Answer: Victoza QD thyroid c-cell carcinoma, more
weight loss, less pancreatitis
QUESTIONS AND ANSWERS VERIFIED 100%
CORRECT
◉ HLA b1502. Answer: Test in Asians. Rash for carbamazepine
(tegretol), phenytoin (Dilantin), fos phenytoin (cerebyx)
◉ Trastuzumab. Answer: Herceptin, her/Neu- ado-trastuzunab
(kadcyla), lapatinib (tykerb) pertuzumab (perjeta)
◉ Hla- b 5701. Answer: Don't give abacavir (ziagen), epzicom,
trizivir
◉ Not cross reactive a/ opioid allergy. Answer: Fentanyl, meperidine
(Demerol), methadone (dolophine), tramadol (ultram), tapentadol
(nucynta)
◉ Inducers. Answer: Ps porcs (phenytoin, smoking, phenobarbital,
oxcarbazepine, rifampin, carbamazepine, St. John's wort)
◉ Inhibitors. Answer: Gpacman (grapefruit, pi's, azoles,
cimetidine/cyclosporine, macrolides- erytho/clarithro, amiodarone,
non dihydro (dilt, verapamil)
,◉ If on amiodarone, decrease these drugs by 30-50%. Answer:
Digoxin, warfarin, quinidine, procainanide, statins
◉ Statins with high risk of inhibition. Answer: Las (lova, atorva,
simva)
◉ Entecavir. Answer: Baraclude. Empty stomach for hep B that fail
lamivudime and adefovir- se: peripheral edema, nephrotoxic
◉ Ribavirin. Answer: Copegus. W/ food bid for hep c, hepatotoxic,
hemolytic anemia, preg x, psych disorders, ci: renal disfxn
◉ Glipizide. Answer: Glucotrol 30 min before break & dinner
◉ Glimeprimide. Answer: Amaryl 1-2 mg qd w/ 1st meal
◉ Glyburide. Answer: Diabeta, + metformin = glucovance, do not use
w/ renal failure 2.5-5mg qd
◉ Rosiglitazone. Answer: Avandia 4-8mg qd (tzd, exacerbate hf, liver
damage, increases hdl, decreases tg/total cholesterol) similar:
pioglitazone (actos)
, ◉ Repaglinide. Answer: Prandin 0.5-2mg TID 15-30 min before a
meal, hypoglycemia- do not take with su's
◉ Nateglinide. Answer: Starlix injection- 15-30 min before meals
◉ Acarbose. Answer: Precose- w/ 1st bite of meal and water
◉ Miglitol. Answer: Glyset w/ 1st bite of meal and water
◉ Linagliptan. Answer: Tradjenta- 5 mg qd in morning with or
without food, no renal adjustment
◉ Saxagliptin. Answer: OnglyZa 2.5-5mg qd
◉ Canaglifozin. Answer: Invokana 100mg qd before first meal of day
for DM. Se: female genital mycotic infxn, increased urination,
hyperkalemia, can increase dig levels, ci: renal dx
◉ Exenatide. Answer: Byetta 30-60 min before am & pm
meals,medguide, pancreatitis, thyroid c-cell carcinoma xr= bydureon
◉ Liraglutide. Answer: Victoza QD thyroid c-cell carcinoma, more
weight loss, less pancreatitis
