TEST BANK - IMMUNOLOGY AND SEROLOGY IN LABORATORY MEDICINE,
7TH EDITION (TURGEON, 2022)
CHAPTER 1-27, ALL CHAPTERS
,TEST BANK FOR
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
Chapter 1-27
Chapter 01: Highlights of the Innate and Adaptive Immune Systems
MULTIPLE CHOICE
1. The ―father‖ of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generally considered to be the ―father of immunology.‖
DIF: Cognitive Level: I
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried
powders derived from the crusts of smallpox lesions.
DIF: Cognitive Level: I
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the body against nonself.
c. amplify specific functions.
d. Both A and B.
ANS: D
The function of the immune system is to recognize self from nonself and defend the body
against nonself. Such a system is necessary for survival. The immune system also has
nonspecific effector mechanisms that usually amplify the specific functions. Nonspecific
components of the immune system include mononuclear phagocytes, polymorphonuclear
leukocytes, and soluble factors (e.g., complement).
DIF: Cognitive Level: I
4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
, c. an vautoimmune vdisorder.
d. recovery vfrom vinfectious vdisease.
ANS: v C
The vdesirable vconsequences vof vimmunity vinclude vnatural vresistance, vrecovery, vand vacquired
vresistance vto vinfectious vdiseases. vA vdeficiency vor vdysfunction vof vthe vimmune vsystem vcan
vcause vmany vdisorders. vUndesirable vconsequences vof vimmunity vinclude vallergy, vrejection vof va
vtransplanted vorgan, vor van vautoimmune vdisorder.
DIF: Cognitive vLevel: vI
5. The vimmune vsystem vhas vvarious vdistinctive vcharacteristics vexcept;
a. specificity.
b. memory.
c. mobility.
d. noncooperation vamong vdifferent vcells.
ANS: v D
The vimmune vsystem vis vcomposed vof va vlarge, vcomplex vset vof vwidely vdistributed velements,
vwith vthe vdistinctive vcharacteristics vof vspecificity, vmemory, vmobility, vreplicability, vand
vcooperation vamong vdifferent vcells vor vcellular vproducts. vSpecificity vand vmemory vare
vcharacteristics vof vlymphocytes vin vthe vimmune vsystem. vNonspecific velements vof vthe vimmune
vsystem vdemonstrate vmobility. vIn vaddition, vspecific vand vnonspecific vcellular vcomponents vof
vthe vimmune vsystem vcan vreplicate. vCooperation vis vrequired vfor voptimal vfunctioning, vand
vinteraction vinvolves vspecific vcellular velements, vcell vproducts, vand vnonlymphoid velements.
DIF: Cognitive vLevel: vI
6. Hematopoiesis voccurs vin vthe vyolk vsac vduring vthe
a. immediate vhours vafter vconception
b. second vmonth vof vgestation.
c. second vtrimester vof vgestation.
d. periods vof vsevere vanemia vin vchildren.
ANS: v A
The vsites vof vblood vcell vdevelopment, vor vhematopoiesis, vfollow va vdefinite vsequence vin vthe
vembryo vand vfetus. vHematopoiesis voccurs vin vthe vyolk vsac vduring vthe vsecond vmonth vof
vgestation.
DIF: Cognitive vLevel: vII
7. The vsequence vof vblood vcell vdevelopment vin vthe vembryo vand vfetus vis
a. yolk vsac, vliver-spleen, vbone vmarrow.
b. yolk vsac, vbone vmarrow, vliver/spleen.
c. liver-spleen, vyolk vsac, vbone vmarrow.
d. bone vmarrow, vliver-spleen, vyolk vsac.
ANS: v A
, The vfirst vblood vcells vare vprimitive vred vblood vcells v(erythroblasts; vRBCs) vformed vin vthe vislets
vof vthe vyolk vsac vduring vthe vfirst v2 vto v8 vweeks vof vlife. vGradually, vthe vliver vand vspleen vreplace
vthe vyolk vsac vas vthe vsites vof vblood vcell vdevelopment. vBy vthe vsecond vmonth vof vgestation, vthe
vliver vbecomes vthe vmajor vsite vof vhematopoiesis, vand vgranular vtypes vof vleukocytes vhave vmade
vtheir vinitial vappearance. vThe vliver vand vspleen vpredominate vfrom vabout v2 vto v5 vmonths vof
vfetal vlife. vIn vthe vfourth vmonth vof vgestation, vbone vmarrow vbegins vto vproduce vblood vcells.
vAfter vthe vfifth vfetal vmonth, vbone vmarrow vbegins vto vassume vits vultimate vrole vas vthe vprimary
vsite vof vhematopoiesis.
DIF: Cognitive vLevel: vII
8. The vprimary vfunction vof vmature vneutrophils vis
a. to vreduce vinflammation.
b. to vlyse vparasites vin vthe vcirculatory vsystem.
c. antigen vrecognition.
d. phagocytosis.
ANS: v D
Various vphagocytic vcells vcontinually vcirculate vthroughout vthe vblood, vlymph, vgastrointestinal
vsystem, vand vrespiratory vtract. vWhen vtrauma voccurs, vthe vneutrophils varrive vat vthe vsite vof vinjury
vand vcan vbe vfound vin vthe vinitial vexudate vin vless vthan v1 vhour. vMonocytes vare vslower vin vmoving
vto vthe vinflammatory vsite. vMacrophages vresident vin vthe vtissues vof vthe vbody vare valready vin
vplace vto vdeal vwith van vintruding vagent. vAdditional vmacrophages vfrom vthe vbone vmarrow vand
vother vtissues vcan vbe vreleased vin vsevere vinfections.
DIF: Cognitive vLevel: vII
9. Primary vgranules, vor vazurophilic vgranules, vin vneutrophils vcontain
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both vA vand vB.
ANS: v D
Granules vin vthe vphagocyte vcytosol vcontain vdegradatory venzymes vof vthree vtypes
1. Primary, vor vazurophilic, vgranules vcontaining venzymes v(e.g.,
vlysozyme, vmyeloperoxidase)
2. Secondary, vor vspecific, vgranules vcontaining vsubstances vsuch vas vlactoferrin.
3. Tertiary vgranules vcontaining vsubstances vsuch vas vcaspases
DIF: Cognitive vLevel: vI
10. The vorigin vof va vcondition vwhen veosinophils vare vincreased vin vthe vcirculating vblood vis
associated vwith:
v
a. fungus
b. parasitic vamoeba
c. allergic vreactions
d. bacteria
ANS: v C
7TH EDITION (TURGEON, 2022)
CHAPTER 1-27, ALL CHAPTERS
,TEST BANK FOR
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
Chapter 1-27
Chapter 01: Highlights of the Innate and Adaptive Immune Systems
MULTIPLE CHOICE
1. The ―father‖ of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generally considered to be the ―father of immunology.‖
DIF: Cognitive Level: I
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried
powders derived from the crusts of smallpox lesions.
DIF: Cognitive Level: I
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the body against nonself.
c. amplify specific functions.
d. Both A and B.
ANS: D
The function of the immune system is to recognize self from nonself and defend the body
against nonself. Such a system is necessary for survival. The immune system also has
nonspecific effector mechanisms that usually amplify the specific functions. Nonspecific
components of the immune system include mononuclear phagocytes, polymorphonuclear
leukocytes, and soluble factors (e.g., complement).
DIF: Cognitive Level: I
4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
, c. an vautoimmune vdisorder.
d. recovery vfrom vinfectious vdisease.
ANS: v C
The vdesirable vconsequences vof vimmunity vinclude vnatural vresistance, vrecovery, vand vacquired
vresistance vto vinfectious vdiseases. vA vdeficiency vor vdysfunction vof vthe vimmune vsystem vcan
vcause vmany vdisorders. vUndesirable vconsequences vof vimmunity vinclude vallergy, vrejection vof va
vtransplanted vorgan, vor van vautoimmune vdisorder.
DIF: Cognitive vLevel: vI
5. The vimmune vsystem vhas vvarious vdistinctive vcharacteristics vexcept;
a. specificity.
b. memory.
c. mobility.
d. noncooperation vamong vdifferent vcells.
ANS: v D
The vimmune vsystem vis vcomposed vof va vlarge, vcomplex vset vof vwidely vdistributed velements,
vwith vthe vdistinctive vcharacteristics vof vspecificity, vmemory, vmobility, vreplicability, vand
vcooperation vamong vdifferent vcells vor vcellular vproducts. vSpecificity vand vmemory vare
vcharacteristics vof vlymphocytes vin vthe vimmune vsystem. vNonspecific velements vof vthe vimmune
vsystem vdemonstrate vmobility. vIn vaddition, vspecific vand vnonspecific vcellular vcomponents vof
vthe vimmune vsystem vcan vreplicate. vCooperation vis vrequired vfor voptimal vfunctioning, vand
vinteraction vinvolves vspecific vcellular velements, vcell vproducts, vand vnonlymphoid velements.
DIF: Cognitive vLevel: vI
6. Hematopoiesis voccurs vin vthe vyolk vsac vduring vthe
a. immediate vhours vafter vconception
b. second vmonth vof vgestation.
c. second vtrimester vof vgestation.
d. periods vof vsevere vanemia vin vchildren.
ANS: v A
The vsites vof vblood vcell vdevelopment, vor vhematopoiesis, vfollow va vdefinite vsequence vin vthe
vembryo vand vfetus. vHematopoiesis voccurs vin vthe vyolk vsac vduring vthe vsecond vmonth vof
vgestation.
DIF: Cognitive vLevel: vII
7. The vsequence vof vblood vcell vdevelopment vin vthe vembryo vand vfetus vis
a. yolk vsac, vliver-spleen, vbone vmarrow.
b. yolk vsac, vbone vmarrow, vliver/spleen.
c. liver-spleen, vyolk vsac, vbone vmarrow.
d. bone vmarrow, vliver-spleen, vyolk vsac.
ANS: v A
, The vfirst vblood vcells vare vprimitive vred vblood vcells v(erythroblasts; vRBCs) vformed vin vthe vislets
vof vthe vyolk vsac vduring vthe vfirst v2 vto v8 vweeks vof vlife. vGradually, vthe vliver vand vspleen vreplace
vthe vyolk vsac vas vthe vsites vof vblood vcell vdevelopment. vBy vthe vsecond vmonth vof vgestation, vthe
vliver vbecomes vthe vmajor vsite vof vhematopoiesis, vand vgranular vtypes vof vleukocytes vhave vmade
vtheir vinitial vappearance. vThe vliver vand vspleen vpredominate vfrom vabout v2 vto v5 vmonths vof
vfetal vlife. vIn vthe vfourth vmonth vof vgestation, vbone vmarrow vbegins vto vproduce vblood vcells.
vAfter vthe vfifth vfetal vmonth, vbone vmarrow vbegins vto vassume vits vultimate vrole vas vthe vprimary
vsite vof vhematopoiesis.
DIF: Cognitive vLevel: vII
8. The vprimary vfunction vof vmature vneutrophils vis
a. to vreduce vinflammation.
b. to vlyse vparasites vin vthe vcirculatory vsystem.
c. antigen vrecognition.
d. phagocytosis.
ANS: v D
Various vphagocytic vcells vcontinually vcirculate vthroughout vthe vblood, vlymph, vgastrointestinal
vsystem, vand vrespiratory vtract. vWhen vtrauma voccurs, vthe vneutrophils varrive vat vthe vsite vof vinjury
vand vcan vbe vfound vin vthe vinitial vexudate vin vless vthan v1 vhour. vMonocytes vare vslower vin vmoving
vto vthe vinflammatory vsite. vMacrophages vresident vin vthe vtissues vof vthe vbody vare valready vin
vplace vto vdeal vwith van vintruding vagent. vAdditional vmacrophages vfrom vthe vbone vmarrow vand
vother vtissues vcan vbe vreleased vin vsevere vinfections.
DIF: Cognitive vLevel: vII
9. Primary vgranules, vor vazurophilic vgranules, vin vneutrophils vcontain
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both vA vand vB.
ANS: v D
Granules vin vthe vphagocyte vcytosol vcontain vdegradatory venzymes vof vthree vtypes
1. Primary, vor vazurophilic, vgranules vcontaining venzymes v(e.g.,
vlysozyme, vmyeloperoxidase)
2. Secondary, vor vspecific, vgranules vcontaining vsubstances vsuch vas vlactoferrin.
3. Tertiary vgranules vcontaining vsubstances vsuch vas vcaspases
DIF: Cognitive vLevel: vI
10. The vorigin vof va vcondition vwhen veosinophils vare vincreased vin vthe vcirculating vblood vis
associated vwith:
v
a. fungus
b. parasitic vamoeba
c. allergic vreactions
d. bacteria
ANS: v C
