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MN553 Pharmacology Unit 6 Questions with Correct Answers| Latest Update

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MN553 Pharmacology Unit 6 Questions with Correct Answers| Latest Update

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MN553 Pharmacology Unit 6 Questions with Correct Answers| Latest Update
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Causes of drug resistance People not completing their antibiotics/inappropriate use,
overuse of broad spectrum ABO's



Every ABO class has_____________________ resistance organisms



Vaccination with pneumococcal vaccine has decreased resistance


Inhibits the biosynthesis of peptidogylcan bacterial cell wall, bactericidal:
Pharmacodynamics of penicillin



4 classes of penicillin penicillin, aminopenicillin, penicillinase-resistant-penicillins,
antipsuedomonal penicillins



Penicillin G, Aqueous penicillin G, Procaine Pcn G, Benzathine Pcn G, PCN V Penicillin class,
works on Strep group A&B (Gram+)



Ampicillin, Amoxicillin Aminopenicillins, work better for gram -, also active against gram +



Methicillin, Nafcillin, Oxacillin, Dicloxacillin Penicillinase-resistant-penicillins (2nd generation
pcn)



penicillinase enzyme produced by bacteria that destroy the beta lactam rink of the antibiotic
making penicillin ineffective.



titarcillin Piperacillin Antipseudomonal penicillin's that are combined with calvulanate

, Carbenicillin antipseudomonal penicillin



Bactericidial inhibits bacterial cell wall synthesis (PCN, Cephalosporins)



Diuretics can interact with PCN, hypo/hyperkalemia



Methotrexate interact with PCN, increase Methotrexate level



Oral Contraceptives PCN may reduce efficacy



Probenecid interact with pcn, delay renal elimination, increase blood levels



Tetracyclines Interact with PCN, due to bacteriostatic action of tetracycline



Warfarin Interact with PCN, increase risk of bleedin



Beta Blockers interact with ampicillin, reduces bioavailability



Allopurinol interacts with ampicillin, more likely to develop rash



Cyclosporine interacts with Nafcillin, produces subtherapeutic cyclosporine levels



Colestipol interacts with PCN G by decreasing absorption



Cholestryramine interacts with PCN, by decreasing absorption

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