EDITION TEST BANK 2026 COMPLETE
SOLUTION GUIDE ALL CHAPTERS 1-20
◉ 2. Which of the following is FALSE about PSA?
A. It is a single-chain glycoprotein
B. It is used as a tumor marker
C. It is not elevated in benign prostatic hyperplasia
D. It is quantified in serum by immunoassays Answer: C. It is not
elevated in benign prostatic hyperplasia.
◉ 3. Which of the following biomarkers is elevated in nonmucinous
epithelial ovarian cancer?
A. CA 15-3
B. CA 19-9
C. CA 125
D. CEA Answer: C. CA 125
◉ 4. Which of the following is a sialylated Lewis blood group antigen
associated with colorectal cancer?
A. CA 125
B. CA 15-3
,C. PSA
D. CA 19-9 Answer: D. CA 19-9
◉ 5. Which of the following biomarkers are elevated in advanced
stages of breast cancer?
A. Total and free PSA
B. CEA and alpha-fetoprotein
C. CA 15-3 and CA 549
D. DUPAN-2 and Gastrin Answer: C. CA 15-3 and CA 549
◉ 6. Which tumor marker is associated with cancer of the urinary
bladder?
A. CA 125
B. CA19-9
C. CA 50
D. Nuclear matrix protein Answer: D. Nuclear matrix protein
◉ 7. What is the primary clinical usefulness of measuring
carcinoembryonic antigen?
A. Diagnosis of lung cancer
B. Diagnosis of colorectal cancer
C. Screening for breast cancer
,D. Monitoring for recurrence of colon cancer Answer: D. Monitoring
for recurrence of colon cancer
◉ 8. Which of the following is used to assess the usefulness of
trastuzumab (Herceptin®) therapy for breast cancer?
A. CA 15-3
B. HER-2/neu
C. CA 125
D. Prolactin Answer: B. HER-2/neu
◉ 9. Which type of hCG test would be most useful to assess a person
suspected of having testicular cancer?
A. Plasma immunoassay for intact hCG and the β-hCG subunits
B. Plasma immunoassay fro the free alpha and β-hCG subunits
C. Urine assay for hCG-β core
D. Plasma immunoassay for intact hCG only Answer: A. Plasma
immunoassay for intact hCG and the β-hCG subunits
◉ 10. A markedly elevated serum AFP is associated with which of
the following?
A. Ovarian cancer
B. Lung cancer
C. Hepatoma
, D. Breast cancer Answer: C. Hepatoma
◉ 11. Which of the following assays is recommended as a screening
test for colorectal cancer in persons over 50 years of age?
A. Fecal typsin
B. AFP
C. BTA
D. Occult blood t test Answer: D. Occult blood test
◉ 12. Which of the following must be determined to calculate
diagnostic specificity?
A. True-negatives and false-positives
B. True-positives and false-positives
C. True-positives and false-negatives
D. True-negatives and false-negatives Answer: A. True-negatives and
false-positives
◉ 13. A new tumor marker assay for prostate specific antigen (PSA)
is evaluated for sensitivity by testing serum samples from patients
who have been diagnosed as having prostate cancer. The following
results were obtained:
Number of prostate cancer patients who tested positive by the new
assay = 42 out 46