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\Q\.Roux-en-Y gastric bypass surgery (RYGB) accounts for about 80% of bariatric procedures in
the US and is usually done laparoscopically. During RYGB, a small part of the proximal stomach is
detached from the rest of the stomach, creating a stomach pouch of < 30 mL. Which of the
following preexisting conditions has been shown to go into remission in up to 62% of patients 6
yr after RYGB?
a. Hypertension
b. Diabetes
c. Obesity
d. Obstructive Sleep Apnea - -Answer: B: Diabetes is particularly likely to remit. Remission rates
are up to 62% after 6 yr. A and D: Other comorbid conditions that tend to abate or resolve after
bariatric surgery include cardiovascular risk factors (eg, dyslipidemia,
hypertension [A], diabetes), cardiovascular disorders, obstructive sleep apnea (D),
osteoarthritis, and depression. C: For RYGB, weight loss is 50 to 65% after 2 yr; weight loss after
RYGB is maintained for up to 10 yr. All-cause mortality decreases by 25%, primarily because
cardiovascular and cancer mortality is reduced.
\Q\.Which of the following procedures is being used increasingly in the US as definitive
treatment for severe obesity (eg, in patients with a body mass index [BMI] > 60)?
a. Sleeve Gastrectomy
b. Roux-en Y Gastric Bypass
c. Adjustable Gastric Banding
d. Vertical Banded Gastroplasty - -Answer: A: Sleeve gastrectomy; because this procedure
causes substantial and sustained weight loss, it is being used increasingly in the US as definitive
treatment for severe obesity. Part of the stomach is removed, creating a tubular
stomach passage. The procedure does not involve anatomic changes to the small intestine. B:
Nonetheless, Roux-en-Y gastric bypass surgery accounts for about 80% of bariatric procedures in
,the US. C: Use of adjustable gastric banding has dramatically decreased in the US. D: Vertical
banded gastroplasty is no longer commonly done because complication rates are high and the
resulting weight loss is insufficient.
\Q\.Contraindications to bariatric surgery include which of the following?
a. Body mass index (BMI) < 30 kg/m2
b. Current drug or alcohol abuse
c. Obstructive sleep apnea
d. High-risk lipid profile - -Answer: B: Current drug or alcohol abuse. A: The use of bariatric
surgery is controversial in patients with a BMI < 30. C and D: To qualify for bariatric surgery,
patients should have a BMI of > 40 or a BMI of > 35 plus a serious complication (eg, diabetes,
hypertension, obstructive sleep apnea [C], high-risk lipid profile [D]).
\Q\.Bariatric Surgery Key Points – Answer -Consider weight loss surgery if patients are
motivated, have not succeeded using nonsurgical treatments, and have a BMI of > 40 kg/m2 or
a BMI of > 35 kg/m2 plus a serious complication (eg, diabetes, hypertension, obstructive sleep
apnea, high-risk lipid profile) or a BMI of 30 to 34.9 with type 2 diabetes and inadequate
glycemic control despite optimal lifestyle and medical therapy.
Weight loss surgery is contraindicated if patients have an uncontrolled psychiatric disorder (eg,
major depression), drug or alcohol abuse, cancer that is not in remission, or another life-
threatening disorder or if they cannot comply with nutritional requirements (including life-long
vitamin replacement when indicated).
The most common procedures are sleeve gastrectomy and Roux-en-Y gastric bypass; use of
adjustable gastric banding has decreased dramatically in the US.
Monitor patients regularly after surgery for maintenance of weight loss, resolution of weight-
related comorbid disorders, and complications of surgery (eg, nutritional deficiencies, metabolic
bone disease, gout, cholelithiasis, nephrolithiasis, depression, alcohol abuse).
, \Q\.Which of the following increases the risk of cardiovascular disorders in patients with
obesity?
a. Osteoporosis
b. Excess abdominal fat
c. Psychological disorders
d. Gastric Ulcer - -Answer: B: Excess abdominal fat. Complications, including
coronary artery disease, are more likely in patients with fat that is concentrated abdominally.
Choices A, C, and D do not increase the risk of cardiovascular disorders in patients with obesity.
\Q\.What is the role of ghrelin in food intake-regulating pathways?
a. It increases food intake.
b. It decreases food intake.
c. Level decreases when weight is lost.
d. It integrates energy balance signals. - -Answer: A: Ghrelin, secreted primarily by the
stomach, increases food intake. B, C, and D: Other hormones and regulatory substances have
these effects.
\Q\.Which type of exercise is MOST effective for increasing BMR?
a. Aerobic exercise
b. Resistance exercise
c. Balancing exercise
d. Flexibility exercise - -Answer: B: Resistance (strengthening) exercises are the most effective
way to increase BMR. Resistance exercises increase muscle mass. Because muscle tissue burns
more calories at rest than does fat tissue, increasing muscle mass produces lasting increases in
BMR. Choices A, C, and D can also be effective in a weight management program. A
combination of aerobic and resistance exercise is better than either alone, particularly when
patients choose activities they enjoy.