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Diabetic Nephropathy: Basic Concepts and Clinical Overview

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This presentation explains diabetic nephropathy in a simple way, describing its main causes, basic mechanisms, and effects on kidney function. The document is written in Spanish and is intended to help students understand this diabetes-related complication.

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Institution
Course

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Uploaded on
January 11, 2026
Number of pages
24
Written in
2025/2026
Type
Presentation
Person
Unknown

Subjects

Content preview

g icos
t ol ó
s Hi s
azg o c os
Hall sc óp i
ic ro
yM

, Temario:
Engrosamiento difuso de la membrana basal
glomerular



Expansión mesangial difusa y nodular


Hialinosis arteriolar (aferente y eferente)

Comparación lámina normal vs. patológica (en vasos)

Esclerosis glomerular global o segmentaria

Atrofia tubular e intersticial + fibrosis

, ¿Qué es la Membrana
Basal Glomerular (MBG)?
La MBG es una estructura especializada situada entre:
Endotelio fenestrado
Podocitos (pedicelos)
Su función:
Filtración selectiva
Barrera física y eléctrica (carga negativa)
Está formada por:
Colágeno tipo IV
LBG
Laminina
Nidógeno
Proteoglicanos (heparán sulfato)
$15.99
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