i i i i
FOR ADVANCED PRACTICE NURSE
i i i i
PRESCRIBERS, 5TH EDITION WOO ROBINSON i i i i i
2025/2026
CHAPTER 1. DRUGS USED IN TREATING BACTERIAL
i i i i i i i
DISEASES
MULTIPLE CHOICE i
IDENTIFY THE CHOICE THAT BEST COMPLETES THE
i i i i i i i
STATEMENT OR ANSWERS THE QUESTION i i i i i
i i i i i i i i i i i i
,1. Factors that place a patient at risk of developing an antimicrobial-resistant organism
i i i i i i i i i i i i i
include:
1. Age over 50 years i i i
2. School attendance 3. Travel within the U.S. i i i i i
4. Inappropriate use of antimicrobials
i i i i
i i 2. Infants and young children are at higher risk of developing antibiotic-resistant
i i i i i i i i i i i i
infections due to: i i
1. Developmental differences in pharmacokinetics of the antibiotics in children i i i i i i i i
2. The fact that children this age are more likely to be in daycare and exposed to
i i i i i i i i i i i i i i i i
pathogens from other children i i i
3. Parents of young children insisting on preventive antibiotics so they don’t miss work
i i i i i i i i i i i i i
when their child is sick
i i i i
4. Immunosuppression from the multiple vaccines they receive in the first 2 years of i i i i i i i i i i i i i
life
i i 3. Providers should use an antibiogram when prescribing. An antibiogram is:
i i i i i i i i i i
1. The other name for the Centers for Disease Control guidelines for prescribing
i i i i i i i i i i i i
antibiotics
2. An algorithm used for prescribing antibiotics for certain infections
i i i i i i i i
3. The reference also known as the Pink Book, published by the Centers for Disease
i i i i i i i i i i i i i i
Control
4. A chart of the local resistance patterns to antibiotics developed by laboratories
i i i i i i i i i i i
i i 4. There is often cross-sensitivity and cross-resistance between penicillins and
i i i i i i i i i i
cephalosporins because: i
1. Renal excretion is similar in both classes of drugs.
i i i i i i i i
2. When these drug classes are metabolized in the liver they both produce resistant
i i i i i i i i i i i i i
enzymes.
3. Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-
i i i i i i i i i i i i
producing organisms. i
,4. There is not an issue with cross-resistance between the penicillins and
i i i i i i i i i i i
cephalosporins.
i 5. Jonathan has been diagnosed with strep throat and needs a prescription for
i i i i i i i i i i i i i
an antibiotic. He says the last time he had penicillin he developed a red, blotchy rash. An
i i i i i i i i i i i i i i i i i
appropriate antibiotic to prescribe would be:
i i i i i
1. Penicillin VK, because his rash does not sound like a serious rash
i i i i i i i i i i i
2. Amoxicillin
3. Cefadroxil (Duricef) i
4. Azithromycin
i 6. Sarah is a 25-year-old female who is 8 weeks pregnant and has a urinary
i i i i i i i i i i i i i i i
tract infection. What would be the appropriate antibiotic to prescribe for her?
i i i i i i i i i i i
1. Ciprofloxacin (Cipro) i
2. Amoxicillin (Trimox) i
3. Doxycycline
4. Trimethoprim-sulfamethoxazole (Septra) i
i
7. Pong-tai is a 12-month-old child who is being treated with amoxicillin for acute
i i i i i i i i i i i i i
otitis media. His parents call the clinic and say he has developed diarrhea. The appropriate
i i i i i i i i i i i i i i i
action would be to:
i i i
1. Advise the parents that some diarrhea is normal with amoxicillin and recommend
i i i i i i i i i i i i
probiotics daily. i
2. Change the antibiotic to one that is less of a gastrointestinal irritant.
i i i i i i i i i i i
3. Order stool cultures for suspected viral pathogens not treated by the amoxicillin.
i i i i i i i i i i i
4. Recommend increased fluids and fiber in his diet. i i i i i i i
, 8. Lauren is a 13-year-old child who comes to clinic with a 4-day history of cough, low-
i i i i i i i i i i i i i i i
grade fever, and rhinorrhea. When she blows her nose or coughs the mucous is greenish-
i i i i i i i i i i i i i i
yellow. The appropriate antibiotic to prescribe would be:
i i i i i i i
1. Amoxicillin
2. Amoxicillin/clavulanate
3. TMP/SMZ (Septra) i
4. None
9. Joanna had a small ventricle septal defect (VSD) repaired when she was 3 years old
i i i i i i i i i i i i i i i
and has no residual cardiac problems. She is now 28 and is requesting prophylactic
i i i i i i i i i i i i i i
antibiotics for an upcoming dental visit. The appropriate antibiotic to prescribe according to
i i i i i i i i i i i i
i current American College of Cardiology and American Heart Association guidelines is:
i i i i i i i i i i
1. None, no antibiotic is required for dental procedures
i i i i i i i
2. Amoxicillin 2 grams 1 hour before the procedure i i i i i i i
3. Ampicillin 2 grams IM or IV 30 minutes before the procedure i i i i i i i i i i
4. Azithromycin 1 gram 1 hour before the procedure i i i i i i i
10. To prevent further development of antibacterial resistance it is recommended that
i i i i i i i i i i i
fluoroquinolones be reserved for treatment of: i i i i i
1. Urinary tract infections in young women i i i i i
2. Upper respiratory infections in adults
i i i i
3. Skin and soft tissue infections in adults
i i i i i i
4. Community-acquired pneumonia in patients with comorbidities i i i i i
11. Fluoroquinolones have a Black Box Warning regarding i i i i i i even months after
i i i
treatment.
1. Renal dysfunction i
2. Hepatic toxicity i
3. Tendon rupture i
4. Development of glaucoma i i