Chapter 01
1. The last cases of smallpox were reported in the
a. 1950s.
b. 1960s.
c. 1970s.
d. 1980s.
e. 1990s.
2. The first line of defense against microorganisms that infect the body is referred to
as __________ immunity.
a. opportunistic
b. innate
c. adaptive
d. primary
e. central
3. Select the correct statement about innate and adaptive immunity.
a. Innate immunity involves cells bearing receptors that are highly specific for
a pathogen.
b. The first response to a pathogen involves immunological memory.
c. Hematopoiesis occurs in the lymph node.
d. Phagocytosis involves the uptake and killing of microbes.
e. Once lymphocytes mature, they remain in lymphoid organs and do not
reenter the blood.
4. Which of the following are chemical barriers of innate immunity?
a. lactic acid and lysozyme
b. lactic acid, lysozyme, and the normal microbiota
c. skin and mucous membranes
, d. neutrophils and macrophages
e. All of these answers are correct.
5. When macrophages secrete __________, an inflammatory response ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines
6. The thin layer of cells that makes up the interior lining of the blood vessels is
called the
a. mucosa.
b. epithelium.
c. endothelium.
d. connective tissue.
e. lymphoid tissue.
7. Identify the incorrect statement regarding hematopoiesis.
a. Hematopoiesis is a continuous process that occurs throughout one’s
lifetime.
b. The location for hematopoiesis differs with age.
c. Self-renewal is necessary to replenish the supply of hematopoietic stem
cells.
d. Most hematopoiesis occurs in the bone marrow after birth.
e. Leukocytes, but not erythrocytes, must go through hematopoiesis to
develop.
8. The progenitors of macrophages are
a. megakaryocytes.
b. dendritic cells.
c. monocytes.
d. neutrophils.
, e. M cells.
9. __________ act as cellular messengers by delivering degraded pathogens to
lymphoid organs.
a. Plasma cells
b. Dendritic cells
c. Large granular lymphocytes
d. Mast cells
e. Basophils
10.Another name for a large granular lymphocyte is a
a. plasma cell.
b. helper T cell.
c. monocyte.
d. natural killer cell.
e. eosinophil.
11.Effector cells that secrete antibodies are known as __________ cells.
a. natural killer
b. cytotoxic T
c. helper T
d. M
e. plasma
12.Spherical regions in lymph nodes containing areas that are packed densely with
proliferating B cells are called
a. efferent vessels.
b. germinal centers.
c. red pulp zones.
d. periarterial lymphoid sheaths.
e. medullary sinuses.