1
WGU D116 Unit 2 Questions with Answers (100%
Correct Answers)
A patient receives a drug that has a narrow therapeutic range. What is
the nurse administering this medication expected to do? Answer:
Monitor plasma drug levels
Narrow therapeutic range is more difficult to administer safely because
the difference between MEC and toxic concentration is small
A patient is receiving intravenous gentamicin. A serum drug test reveals
toxic levels. The dosing is correct, and this medication has been
tolerated by this patient in the past.
What is a probable cause of the test result? Answer: The pt is taking
another medication that binds to serum albumin
BGentamicin binds to albumin but weakly. In presence of another drug
that binds to albumin, gentamicin can rise to toxic levels in blood
stream
What are the components of pharmacokinetics? Answer: Absorption,
distribution, metabolism, excretion
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, 2
Does the volume of distribution increase or decrease as the
concentration of a drug in the blood plasma increases? Answer:
DECREASES
A patient reports becoming "immune" to a medication because it no
longer works to alleviate symptoms.
The provider recognizes that this decreased effectiveness is likely
caused by what? Answer: Desensitization of receptor sites by continual
exposure to the drug
Continual exposure to an agonist would cause the cell to become less
responsive or desensitized
What occurs when a drug binds to a receptor in the body? Answer: It
increases or decreases the activity of that receptor
Which pharmacodynamic principle is most correlated with drug
toxicity? Answer: Therapeutic index
Which is calculated by dividing the median toxic dose by the median
efficacious dose
© 2025 All rights reserved
WGU D116 Unit 2 Questions with Answers (100%
Correct Answers)
A patient receives a drug that has a narrow therapeutic range. What is
the nurse administering this medication expected to do? Answer:
Monitor plasma drug levels
Narrow therapeutic range is more difficult to administer safely because
the difference between MEC and toxic concentration is small
A patient is receiving intravenous gentamicin. A serum drug test reveals
toxic levels. The dosing is correct, and this medication has been
tolerated by this patient in the past.
What is a probable cause of the test result? Answer: The pt is taking
another medication that binds to serum albumin
BGentamicin binds to albumin but weakly. In presence of another drug
that binds to albumin, gentamicin can rise to toxic levels in blood
stream
What are the components of pharmacokinetics? Answer: Absorption,
distribution, metabolism, excretion
© 2025 All rights reserved
, 2
Does the volume of distribution increase or decrease as the
concentration of a drug in the blood plasma increases? Answer:
DECREASES
A patient reports becoming "immune" to a medication because it no
longer works to alleviate symptoms.
The provider recognizes that this decreased effectiveness is likely
caused by what? Answer: Desensitization of receptor sites by continual
exposure to the drug
Continual exposure to an agonist would cause the cell to become less
responsive or desensitized
What occurs when a drug binds to a receptor in the body? Answer: It
increases or decreases the activity of that receptor
Which pharmacodynamic principle is most correlated with drug
toxicity? Answer: Therapeutic index
Which is calculated by dividing the median toxic dose by the median
efficacious dose
© 2025 All rights reserved
