1|Page
NUR 641E Midterm Study Guide,Most Recent Exam
2026 Actual Comprehensive Real Exam Questions And
Verified Answers ||Verified Exam!!!(100% Correct
Answers) Already Graded A+ | Guaranteed Success
||Just Released!!
Pharmacokinetics involves - Answers-a: Absorption:
absorption from the administration site either directly or
indirectly into the blood/plasma.
b: Distribution: reversibly or irreversibly move from the
bloodstream into the interstitial and intracellular fluid.
c: Metabolism: biotransformed via hepatic metabolism or
by other tissues.
d: Elimination: the drug and its metabolites are eliminated
from the body
The route of administration with the highest bioavailability
is - Answers-Intravenous, putting an entire dose into a
patient's vein and bypassing absorption
,2|Page
Intravenous route avoids - Answers-First-pass metabolism
in the liver
Rectal administration has - Answers-variable and erratic
absorption
Steady State (SS) is usually reached within - Answers-4-5
half-lives of a drug
Half-life of a drug is - Answers-How long it takes for the
drug to be excreted from the body
- determines how frequently the drug must be
administered
- predicts how long toxic effects can last
First-order (linear) pharmacokinetics means - Answers-
The metabolism is directly proportional to the free
concentration of the drug
Zero-order (nonlinear) pharmacokinetics means -
Answers-A drug is metabolized at a constant rate per unit
time
,3|Page
CYP3A4 substrate drugs may have a decreased activity if
- Answers-Any CYP3A4 inducer drugs are used along with
it
Drug development process involves these steps according
to the FDA - Answers-a: Discovery: laboratory research to
develop the new drugs
b: Preclinical research with animal testing for safety
c: Clinical research on healthy human subjects to assess
medication pharmacokinetics (Phase 1)
d: Clinical research in humans primarily for medication
safety, usually in a population for which the treatment is
intended (Phase 2)
e: Clinical research in humans comparing the new drug to
accept medications or placebo for efficacy and safety
(Phase 3)
, 4|Page
f: FDA review of the results to determine approval
g: Post marketing study to identify adverse effects not
found in earlier clinical studies (Phase 4)
Medication safety organizations include the Food and
Drug Administration (FDA), the Institute for Safe
Medication Practices (ISMP), and the Joint Commission
on Accreditation of Healthcare Organizations (JCAHO) -
Answers-a: The Institute for Safe Medication Practices
(ISMP)
b: The Institute of Medicine (IOM)
c: The Joint Commission
d: The National Coordinating Counsil for Medication Error
Reporting and Prevention (NCC MERP)
e: Food and Drug Administration (FDA) Safe Use Initiative
NUR 641E Midterm Study Guide,Most Recent Exam
2026 Actual Comprehensive Real Exam Questions And
Verified Answers ||Verified Exam!!!(100% Correct
Answers) Already Graded A+ | Guaranteed Success
||Just Released!!
Pharmacokinetics involves - Answers-a: Absorption:
absorption from the administration site either directly or
indirectly into the blood/plasma.
b: Distribution: reversibly or irreversibly move from the
bloodstream into the interstitial and intracellular fluid.
c: Metabolism: biotransformed via hepatic metabolism or
by other tissues.
d: Elimination: the drug and its metabolites are eliminated
from the body
The route of administration with the highest bioavailability
is - Answers-Intravenous, putting an entire dose into a
patient's vein and bypassing absorption
,2|Page
Intravenous route avoids - Answers-First-pass metabolism
in the liver
Rectal administration has - Answers-variable and erratic
absorption
Steady State (SS) is usually reached within - Answers-4-5
half-lives of a drug
Half-life of a drug is - Answers-How long it takes for the
drug to be excreted from the body
- determines how frequently the drug must be
administered
- predicts how long toxic effects can last
First-order (linear) pharmacokinetics means - Answers-
The metabolism is directly proportional to the free
concentration of the drug
Zero-order (nonlinear) pharmacokinetics means -
Answers-A drug is metabolized at a constant rate per unit
time
,3|Page
CYP3A4 substrate drugs may have a decreased activity if
- Answers-Any CYP3A4 inducer drugs are used along with
it
Drug development process involves these steps according
to the FDA - Answers-a: Discovery: laboratory research to
develop the new drugs
b: Preclinical research with animal testing for safety
c: Clinical research on healthy human subjects to assess
medication pharmacokinetics (Phase 1)
d: Clinical research in humans primarily for medication
safety, usually in a population for which the treatment is
intended (Phase 2)
e: Clinical research in humans comparing the new drug to
accept medications or placebo for efficacy and safety
(Phase 3)
, 4|Page
f: FDA review of the results to determine approval
g: Post marketing study to identify adverse effects not
found in earlier clinical studies (Phase 4)
Medication safety organizations include the Food and
Drug Administration (FDA), the Institute for Safe
Medication Practices (ISMP), and the Joint Commission
on Accreditation of Healthcare Organizations (JCAHO) -
Answers-a: The Institute for Safe Medication Practices
(ISMP)
b: The Institute of Medicine (IOM)
c: The Joint Commission
d: The National Coordinating Counsil for Medication Error
Reporting and Prevention (NCC MERP)
e: Food and Drug Administration (FDA) Safe Use Initiative
