AHN 577 Infectious Disease Part 2
Questions and Correct Answers/ Latest
Update / Already Graded
Isoniazid x 9 months
Ans: Latent TB prevention
Rifampin daily x 4 months
Ans: Latent TB with positive TB skin test or IGRA
Contraindicated d/t risk for severe liver injury or death
Ans: Rifampin + Pyrazinamide combo use in latent TB
RIPE (Rifampin, Isoniazid, Pyrazinimide, Ethambutol) x 8 weeks
Ans: Active TB treatment during intensive phase
Isoniazid and Rifampin x 18 weeks
Ans: Active TB treatment during continuation phase
- Coughing
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- Cavity in lung
- Sputum smears positive for AFB
- TB disease of lungs, airway, or larynx present
- Positive culture
Ans: TB patient infectious if..
- Symptoms improved AND
- 3 consecutive negative sputum smears AND
- Adhering to adequate treatment x 2 weeks
Ans: TB patient no longer infectious if..
-- ELISA - initial screening; 99.9% sensitive
-- Western blot - > 99.99% sensitive and specific
Ans: How do you test for HIV infection?
-- CD4 count - best indicator of immune fx; guides therapy
-- HIV RNA - amt of actively replicating viruses; best indicator for
diagnosing acute HIV infections; tells about disease progression
-- CBC - detect pancytopenia
-- CMP - assess renal/hepatic function
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-- Pregnancy test - prior to ARTs
-- UA to detect early nephropathy
-- Hgb A1c to assess for glucose intolerance
Ans: Routine labs for treatment of HIV/AIDS
1 integrase inhibitor (or PI) + 2 NRTIs
Ans: Typical initial regimen for HIV
Tenofovir, Emtricitabine, Abacavir, Lamivudine
Ans: NRTI examples
- Hepatitis
- Neutropenia
- AKI
- Anemia
- Rash
- Peripheral neuropathy
- GI upset
Ans: Common s/e of NRTIs
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