ATI VIRTUAL PHARM ASSESSMENT EXAM
SCRIPT 2026 COMPLETE QUESTIONS AND
SOLUTIONS GRADED A+
⩥ Muscle Relaxants (Direct Acting on Skeletal Muscle): Dantrolene.
Answer: -Uses: treat and prevent malignant hyperthermia
-Can also be used to reduce muscle spasticity in MS, CP, and SCI
-MOA: prevents release of calcium in the muscles to inhibit muscle
contractions and decrease spasticity
-SE: drowsiness, muscle weakness, gi upset, hepatotoxicty (black box
warning!!!)
-Key Points: for hepatotoxicty, monitor liver enzymes and monitor for
liver damage
⩥ Muscle Relaxants (Centrally Acting): Baclofen. Answer: -Uses: to
treat muscle spasticity related to spinal cord injury, MS or cerebral palsy
-MOA: increases effect of GABA in CNS which reduces spasticity
-SE: drowsiness, nausea, constipation
-Key Points: have patients increase fluid and fiber intake
⩥ Gout. Answer: caused by a build-up of uric acid in the body which
forms crystals which affect the joints and cause pain/inflammation in the
joints (toes affected)
,⩥ Antigout Medication (for acute gout attacks): Colchicine. Answer: -
Uses: acute gout attacks
-MOA: reduces pain and inflammation by interfering with WBCs
-SE: gi upset, thrombocytopenia
-Education: increase fluid intake, DO NOT CONSUME GRAPEFRUIT
JUICE
⩥ Antigout Medications (for chronic gout): Probenecid. Answer: -MOA:
helps to treat hyperuricemia (too much uric acid in the blood) by
inhibiting renal absorption of uric acid (makes it secrete)
-SE: renal calculi (kidney stones, gi upset
-Interventions: monitor uric acid levels, monitor renal function, for renal
calculi: increase fluid intake to prevent
⩥ Antigout Medication (Xanthine Oxidase Inhibitor): Allopurinol.
Answer: -Hint: purifies and gets rid of all that uric acid
-MOA: treats hyperuricemia with chronic gout by inhibiting uric acid
production in first place
-SE: gi upset, rash, hepatotoxicity, nephrotoxicity
-Pt education: increase fluid intake, monitor renal and liver function,
takes 2-6 weeks to see improvement in symptoms
, ⩥ Immunosuppressants: Methotrexate. Answer: -Uses: rheumatoid
arthritis, psoriasis, types of cancer
-MOA: inhibits folic acid metabolism which prevents cell reproduction
-SE: risk of infection, hepatoxicity, bone marrow suppression, gi upset
-education: avoid eating fresh fruit and veggies, avoid contact with sick
people
-Key Points: notify provider of infection, monitor CBC and liver
function tests
⩥ Cyclosporine. Answer: -Uses: ulcerative colitis, rheumatoid arthritis,
prevention of graft vs. host disease in transplant patients
-MOA: inhibits normal immune response by blocking interleuken-2
-SE: increased infection risk, hepatotoxicity, nephrotoxicity, gi upset
-Key Points: notify provider of s/s of infection, monitor liver function
and renal function
⩥ Antimalarial Medication: Hydroxychloroquine. Answer: -Uses: as a
drug for malaria, but also suppresses immune system for RA
-SE: retinal damage (encourage routine eye exams!!!)
⩥ Any meds ending in -mab or -nib are usually immunosuppressants:.
Answer: SE: increased risk for infection!!!
SCRIPT 2026 COMPLETE QUESTIONS AND
SOLUTIONS GRADED A+
⩥ Muscle Relaxants (Direct Acting on Skeletal Muscle): Dantrolene.
Answer: -Uses: treat and prevent malignant hyperthermia
-Can also be used to reduce muscle spasticity in MS, CP, and SCI
-MOA: prevents release of calcium in the muscles to inhibit muscle
contractions and decrease spasticity
-SE: drowsiness, muscle weakness, gi upset, hepatotoxicty (black box
warning!!!)
-Key Points: for hepatotoxicty, monitor liver enzymes and monitor for
liver damage
⩥ Muscle Relaxants (Centrally Acting): Baclofen. Answer: -Uses: to
treat muscle spasticity related to spinal cord injury, MS or cerebral palsy
-MOA: increases effect of GABA in CNS which reduces spasticity
-SE: drowsiness, nausea, constipation
-Key Points: have patients increase fluid and fiber intake
⩥ Gout. Answer: caused by a build-up of uric acid in the body which
forms crystals which affect the joints and cause pain/inflammation in the
joints (toes affected)
,⩥ Antigout Medication (for acute gout attacks): Colchicine. Answer: -
Uses: acute gout attacks
-MOA: reduces pain and inflammation by interfering with WBCs
-SE: gi upset, thrombocytopenia
-Education: increase fluid intake, DO NOT CONSUME GRAPEFRUIT
JUICE
⩥ Antigout Medications (for chronic gout): Probenecid. Answer: -MOA:
helps to treat hyperuricemia (too much uric acid in the blood) by
inhibiting renal absorption of uric acid (makes it secrete)
-SE: renal calculi (kidney stones, gi upset
-Interventions: monitor uric acid levels, monitor renal function, for renal
calculi: increase fluid intake to prevent
⩥ Antigout Medication (Xanthine Oxidase Inhibitor): Allopurinol.
Answer: -Hint: purifies and gets rid of all that uric acid
-MOA: treats hyperuricemia with chronic gout by inhibiting uric acid
production in first place
-SE: gi upset, rash, hepatotoxicity, nephrotoxicity
-Pt education: increase fluid intake, monitor renal and liver function,
takes 2-6 weeks to see improvement in symptoms
, ⩥ Immunosuppressants: Methotrexate. Answer: -Uses: rheumatoid
arthritis, psoriasis, types of cancer
-MOA: inhibits folic acid metabolism which prevents cell reproduction
-SE: risk of infection, hepatoxicity, bone marrow suppression, gi upset
-education: avoid eating fresh fruit and veggies, avoid contact with sick
people
-Key Points: notify provider of infection, monitor CBC and liver
function tests
⩥ Cyclosporine. Answer: -Uses: ulcerative colitis, rheumatoid arthritis,
prevention of graft vs. host disease in transplant patients
-MOA: inhibits normal immune response by blocking interleuken-2
-SE: increased infection risk, hepatotoxicity, nephrotoxicity, gi upset
-Key Points: notify provider of s/s of infection, monitor liver function
and renal function
⩥ Antimalarial Medication: Hydroxychloroquine. Answer: -Uses: as a
drug for malaria, but also suppresses immune system for RA
-SE: retinal damage (encourage routine eye exams!!!)
⩥ Any meds ending in -mab or -nib are usually immunosuppressants:.
Answer: SE: increased risk for infection!!!
