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Exam 2 NUR 3125 Hematology Patho Objectives UCF Test Questions All Answered Correct 2026 Edition.

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Describe erythropoiesis and elements needed to promote effective RBC production. - Answer ** production of RBC's stimulated by erythropoietin (from kidneys) ** Protein (amino acid) Synthesis component of plasma membrane ↓ strength, elasticity, flexibility of plasma membrane, hemolytic anemia Intrinsic factor GI absorption of vit B12 Pernicious anemia Cobalamin (vit B12) Synthesis of DNA and RNA, maturation of erythrocytes, facilitator, folate metabolism Macrocytic (megaloblastic anemia) Folate (folic acid) Synthesis of DNA & RNA, maturation of erythrocytes Macrocytic (megaloblastic anemia) Vit B6 (pyridoxine) Heme synthesis, possibly ↑folate metabolism Hypochromic-microcytic anemia Vit B2 (riboflavin) Oxidative reactions Normochromic-normocytic anemia Vit C (ascorbic acid) Iron metabolism, acts as a reducing agent to maintain iron in its ferrous form Normochromic-normocytic anemia Pantothenic acid Heme synthesis Unknown in humans* Niacin none, but needed for respiration in mature erythrocytes Unknown in humans Vit E Synthesis of heme, possible protection against oxidative damage in mature erythrocytes Hemolytic anemia with ↑ cell membrane fragility, shortens life span of erythrocytes with CF Iron Hemoglobin synthesis Iron-deficiency anemia Copper Structural component of plasma membrane Hypochromic-microcytic anemia

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January 6, 2026
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Exam 2 NUR 3125 Hematology Patho
Objectives UCF Test Questions All
Answered Correct 2026 Edition.
Describe erythropoiesis and elements needed to promote effective RBC production. - Answer
** production of RBC's stimulated by erythropoietin (from kidneys) **



Protein (amino acid) Synthesis component of plasma membrane ↓ strength, elasticity, flexibility
of plasma membrane, hemolytic anemia



Intrinsic factor GI absorption of vit B12 Pernicious anemia



Cobalamin (vit B12) Synthesis of DNA and RNA, maturation of erythrocytes, facilitator, folate
metabolism Macrocytic (megaloblastic anemia)



Folate (folic acid) Synthesis of DNA & RNA, maturation of erythrocytes Macrocytic
(megaloblastic anemia)



Vit B6 (pyridoxine) Heme synthesis, possibly ↑folate metabolism Hypochromic-microcytic
anemia



Vit B2 (riboflavin) Oxidative reactions Normochromic-normocytic anemia



Vit C (ascorbic acid) Iron metabolism, acts as a reducing agent to maintain iron in its ferrous
form Normochromic-normocytic anemia



Pantothenic acid Heme synthesis Unknown in humans*



Niacin none, but needed for respiration in mature erythrocytes Unknown in humans



Vit E Synthesis of heme, possible protection against oxidative damage in mature erythrocytes
Hemolytic anemia with ↑ cell membrane fragility, shortens life span of erythrocytes with CF

, What are causes of anemic conditions? - Answer o Impaired erythrocyte production

o Acute or chronic blood loss

o Increased erythrocyte destruction

> caused by deformities or premature distruction <

o Combination of the above



Differentiate the various types of anemias - Answer Cytic = changes in size

> Macrocytic

> microcytic

> normocytic



Chromic = changes in hemoglobin content

> Normochromic

> hypochromic



Identify normal physiologic adaptations to anemia. - Answer > Movement of interstitial fluid
into plasma ("thins" the blood)



> Blood flow becomes turbulent, creates

hyperdynamic state, vessels dialate (due to hypoxemia), more peripheral blood flow/venous
return



> Increased heart rate (tachycardia), higher stroke vol, failure ensues due to "high output"



> Cardiomyopathy and heart valve insufficiency



> Respiratory rate increases, especially with activity



> Skin color changes, Pallor due to reduced hemoglobin, Loss of elasticity, graying of hair




> Renal changes, Aldosterone secretion (means more NaCL = more water)

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