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Blood Bank ASCP Questions and
Answers Latest 2026
Which is the best component to treat a patient with
fibrinogen deficiency? Ans: Cryoprecipitated AHF
All of the following are cause for donor deferral EXCEPT?
Ans: An individual weighs 115 pounds at the time of
donor screening
A 27-year-old female presents to her physician after
suffering a spontaneous abortion. Though rare, which
antibody may be the etiological agent? Ans: Anti-P
Recombinant Factor IX is indicated for which of the
following? Ans: Hemophilia B
Donor red blood cells (RBCs) were collected on July 12th
of this year. The RBCs were then frozen in glycerol on
July 17th (5 days later) and stored at -65o C.
What should the expiration date read on the frozen RBC
unit? Ans: July 12th; 10 years from collection date
A patient is experiencing prolonged bleeding following a
transfusion. The complete blood count indicates that the
patient's platelet count has decreased following the
transfusion. What is the most likely cause of this issue?
Ans: Posttransfusion purpura
© 2025 All rights reserved
, 2 | Page
Rh Immune Globulin (RhIG) is used to prevent the active
immunization to the D antigen in women who are Rh
negative carrying an Rh positive fetus. One dose of RhIG
(equal to 300 µg of World Health Organization reference
material) contains enough anti-D to protect against: Ans:
30 mL of whole blood
Which of the following characteristics of hemolytic
disease of the fetus and newborn (HDFN) is NOT different
for ABO and Rh HDFN? Ans: Antibody is IgG
ABO blood groups were discovered by: Ans: Landsteiner
When would unexpected positive reactions be
encountered during ABO forward typing? Ans: Acquired
B antigen
Which of the following choices is the basic technique
used to detect unexpected antibodies with a commercial
set of reagent cells? Ans: Indirect antiglobulin test
A pregnant female has been injected with Rh Immune
Globulin (RhIG) antenatally (28 weeks gestation) and has
a positive antibody screen at delivery. The antibody has
been confirmed as anti-D alone and reacts only weakly
(1+ in the indirect antiglobulin test). This antibody may
be the result of: Ans: Passive anti-D (RhIg) received at 28
weeks.
Whole blood or red blood cell units will be shipped from
the American Red Cross to the transfusion facility. At
what temperature should the units be kept during
transportation? Ans: 1-10 °C
© 2025 All rights reserved
Blood Bank ASCP Questions and
Answers Latest 2026
Which is the best component to treat a patient with
fibrinogen deficiency? Ans: Cryoprecipitated AHF
All of the following are cause for donor deferral EXCEPT?
Ans: An individual weighs 115 pounds at the time of
donor screening
A 27-year-old female presents to her physician after
suffering a spontaneous abortion. Though rare, which
antibody may be the etiological agent? Ans: Anti-P
Recombinant Factor IX is indicated for which of the
following? Ans: Hemophilia B
Donor red blood cells (RBCs) were collected on July 12th
of this year. The RBCs were then frozen in glycerol on
July 17th (5 days later) and stored at -65o C.
What should the expiration date read on the frozen RBC
unit? Ans: July 12th; 10 years from collection date
A patient is experiencing prolonged bleeding following a
transfusion. The complete blood count indicates that the
patient's platelet count has decreased following the
transfusion. What is the most likely cause of this issue?
Ans: Posttransfusion purpura
© 2025 All rights reserved
, 2 | Page
Rh Immune Globulin (RhIG) is used to prevent the active
immunization to the D antigen in women who are Rh
negative carrying an Rh positive fetus. One dose of RhIG
(equal to 300 µg of World Health Organization reference
material) contains enough anti-D to protect against: Ans:
30 mL of whole blood
Which of the following characteristics of hemolytic
disease of the fetus and newborn (HDFN) is NOT different
for ABO and Rh HDFN? Ans: Antibody is IgG
ABO blood groups were discovered by: Ans: Landsteiner
When would unexpected positive reactions be
encountered during ABO forward typing? Ans: Acquired
B antigen
Which of the following choices is the basic technique
used to detect unexpected antibodies with a commercial
set of reagent cells? Ans: Indirect antiglobulin test
A pregnant female has been injected with Rh Immune
Globulin (RhIG) antenatally (28 weeks gestation) and has
a positive antibody screen at delivery. The antibody has
been confirmed as anti-D alone and reacts only weakly
(1+ in the indirect antiglobulin test). This antibody may
be the result of: Ans: Passive anti-D (RhIg) received at 28
weeks.
Whole blood or red blood cell units will be shipped from
the American Red Cross to the transfusion facility. At
what temperature should the units be kept during
transportation? Ans: 1-10 °C
© 2025 All rights reserved
