HESI A2 Exam 2026 – Updated Practice Questions, Study Guide, and Comprehensive Review for Nursing Students

1|Page


HESI A2 Anatomy and Physiology (NEW UPDATED VERSION) LATEST ACTUAL EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED QUESTIONS AND ANSWERS) |
GUARANTEED PASS A+ UPDATED 2027



WHICH IS AN ANTERIOR FEATURE OF THE HUMAN HEAD?

A. THE NOSE
B. THE EARS
C. THE OCCIPITAL LOBE
D. THE TEMPORAL LOBE - CORRECT ANSWER THE NOSE

QUESTION : WHAT IS THE PRIMARY HORMONE SECRETED BY THE THYROID?

A. OXYTOCIN
B. TSH
C. ADRENALINE
D. T4 (THYROXINE) - CORRECT ANSWER T4 (THYROXINE)

QUESTION : ENLARGEMENT OF THE THYROID, COMMONLY KNOWN AS A
GOITER, MIGHT BE EXPECTED TO AFFECT__________.

A. SWALLOWING
B. INSULIN LEVELS
C. SLEEP
D. DIGESTION - CORRECT ANSWER SWALLOWING

QUESTION : WHICH KINDS OF MUSCLES ARE INVOLVED IN PERISTALSIS?

A. SMOOTH MUSCLES
B. CARDIAC MUSCLES
C. SKELETAL MUSCLES
D. EPAXIAL MUSCLES - CORRECT ANSWER SMOOTH MUSCLES

QUESTION : WHAT MIGHT AN INJURY TO THE PARIETAL LOBE EFFECT?

A. BREATHING
B. ATTENTION
C. MEMORY
D. PERCEPTION - CORRECT ANSWER PERCEPTION

QUESTION : WHY MIGHT CERTAIN YOUNG PEOPLE BE UNDERWEIGHT?

A. THEY ARE GROWING IN HEIGHT FASTER THAN THEY ARE GAINING WEIGHT.
B. THEY EAT LITTLE PROTEIN AND TOO MUCH FAT AND SUGAR.


2026 2027 GRADED A+

,2|Page


C. THEY EAT SEVERAL MEALS A DAY AND FAIL TO EXERCISE ENOUGH.
D. THEY SELDOM EAT A MEAL THAT CONTAINS FOODS FROM ALL FOOD
GROUPS. - CORRECT ANSWER THEY ARE GROWING IN HEIGHT FASTER
THAN THEY ARE GAINING WEIGHT.

QUESTION : HOW DOES THE DIGESTIVE SYSTEM WORK WITH THE URINARY
SYSTEM?

A. THE DIGESTIVE SYSTEM CONTROLS THE FUNCTIONS OF THE URETER.
B. THE URINARY SYSTEM REMOVES TOXINS FROM THE PRODUCTS OF
URINATION.
C. THE DIGESTIVE SYSTEM MANUFACTURES HORMONES THAT INFLUENCE
URINATION.
D. THE URINARY SYSTEM ELIMINATES SOME WASTE PRODUCTS OF
DIGESTION. - CORRECT ANSWER THE URINARY SYSTEM ELIMINATES
SOME WASTE PRODUCTS OF DIGESTION.

QUESTION : WHICH GLAND IS LOCATED SUPERIOR TO THE KIDNEY?

A. PITUITARY
B. ADRENAL
C. HYPOTHALAMUS
D. PANCREAS - CORRECT ANSWER ADRENAL

QUESTION : TO WHAT TWO SYSTEMS MIGHT THE URETHRA BELONG?

A. REPRODUCTIVE AND ENDOCRINE
B. URINARY AND REPRODUCTIVE
C. ENDOCRINE AND URINARY
D. DIGESTIVE AND CARDIOVASCULAR - CORRECT ANSWER URINARY AND
REPRODUCTIVE

QUESTION : THE AXIAL SKELETAL SYSTEM CONTAINS ALL OF THESE
EXCEPT_______________.

A. THE SKULL
B. THE RIBS
C. THE BREASTBONE
D. THE RADIUS - CORRECT ANSWER THE RADIUS

QUESTION : THE GALL BLADDER IS PART OF THE ________________.

A. ENDOCRINE SYSTEM
B. URINARY SYSTEM
C. DIGESTIVE SYSTEM


2026 2027 GRADED A+

,3|Page


D. NERVOUS SYSTEM - CORRECT ANSWER THE DIGESTIVE SYSTEM

QUESTION : WHICH IS not AN EXAMPLE OF A NONSPECIFIC IMMUNE
RESPONSE?

A. INFLAMMATION
B. VASODILATION
C. RELEASES OF HISTAMINE
D. PRODUCTION OF ANTIBODIES - CORRECT ANSWER PRODUCTION OF
ANTIBODIES

QUESTION : WHICH ORGAN SYSTEM IS PRIMARILY RESPONSIBLE FOR
REGULATING ELECTROLYTES?

A. THE ENDOCRINE SYSTEM
B. THE URINARY SYSTEM
C. THE LYMPHATIC SYSTEM
D. THE NERVOUS SYSTEM - CORRECT ANSWER THE URINARY SYSTEM

QUESTION : WHAT IS THE FUNCTION OF THE CORONARY ARTERY?

A. IT CARRIES OXYGENATED BLOOD TO THE HEART.
B. IT CARRIES DEOXYGENATED BLOOD TO THE LUNGS.
C. IT DISTRIBUTES BLOOD TO THE BODY.
D. IT SUPPLIES BLOOD TO THE HEART MUSCLES. - CORRECT ANSWER IT
SUPPLIES BLOOD TO THE HEART MUSCLES.

QUESTION : WHAT CONDITION MIGHT RESULT FROM LACK OF VITAMIN C?

A. KWASHIORKOR
B. PELLAGRA
C. RICKETS
D. SCURVY - CORRECT ANSWER SCURVY

QUESTION : HOW DOES THE MUSCULAR SYSTEM WORK WITH THE SKELETAL
SYSTEM?

A. MUSCLES ATTACHED TO TENDONS CONTRACT TO BEND THE SKELETON AT
THE JOINTS.
B. THE HARD BONES OF THE SKELETON PROTECT THE VOLUNTARY MUSCLES
OF THE LIMBS.
C. THE CARDIAC MUSCLES PRODUCE CALCIUM THAT IS NEEDED FOR STURDY
BONES.




2026 2027 GRADED A+

, 4|Page


D. SMOOTH MUSCLES ON INTERNAL ORGANS LEACH EXCESS MINERALS FROM
THE BONES. - CORRECT ANSWER MUSCLES ATTACHED TO TENDONS
CONTRACT TO BEND THE SKELETON AT THE JOINTS.

QUESTION : WHICH IS not PRODUCED BY THE PITUITARY GLAND?

A. FSH
B. TRH
C. LH
D. ADH - CORRECT ANSWER TRH

QUESTION : THE RIBS ARE ____________ TO THE LUNGS IN THE HUMAN BODY?

A. MEDIAL
B. SUPERIOR
C. ANTERIOR
D. DEEP - CORRECT ANSWER ANTERIOR

QUESTION : WHAT IS THE NORMAL pH OF HUMAN ARTERIAL BLOOD?

A. 6.8
B. 7.4
C. 7.9
D. 8.2 - CORRECT ANSWER 7.4

QUESTION : WHICH CUT IS CONSIDERED A CROSS SECTION?

A. SAGITTAL OR FRONTAL SECTION
B. A CUT ALONG THE CORONAL PLANE
C. A CUT ALONG THE MEDIAN PLANE
D. A CUT THROUGH THE TRANSVERSE PLANE - CORRECT ANSWER A CUT
THROUGH THE TRANSVERSE PLANE

QUESTION : WHICH ENZYME FUNCTIONS TO BREAK DOWN SPECIFIC SUGAR?

A. CATALASE
B. LIPASE
C. PROTEASE
D. LACTOSE - CORRECT ANSWER LACTOSE

QUESTION : THE HYPOTHALAMUS IS PART OF THE _______________.

A. CARDIOVASCULAR SYSTEM
B. ENDOCRINE SYSTEM
C. RESPIRATORY SYSTEM


2026 2027 GRADED A+