Applied Pharmacology for The Dental Hygienist 9th
x@ x@ x@ x@ x@ x@ x@
Edition by Elena Bablenis Haveles
x@ x@ x@ x@
Complete Test Bank
x@ x@
,Chapter 01: Information Sources, Regulatory Agencies, Drug Legislation, and Prescription
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
Writing
Haveles: Applied Pharmacology for the Dental Hygienist, 9th Edition
x@ x@ x@ x@ x@ x@ x@ x@
MULTIPLE CHOICE x@
1. Knowledge of pharmacology aids the dental professional in
x@ x@ x@ x@ x@ x@ x@
a. obtaining a patient’s health history. x@ x@ x@ x@
b. administering drugs in the office. x@ x@ x@ x@
c. handling emergency situations. x@ x@
d. selection of a nonprescription medicatio x@ x@ x@ x@
n.
e. All of the above. x@ x@ x@
ANS: x @ E
All of the choices are true. Because many of our patients are being treated with drugs, knowl
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
edge of pharmacology helps in understanding and interpreting patients’ responses to health hist
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ory questions. Knowledge of the therapeutic and adverse effects of medications obviously help
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
s in their proper administration in the office. Emergency situations may be caused by drugs o
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
r treated by drugs; thus, knowledge of pharmacology is of great help, especially because a rap
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
id response is sometimes required. A clear understanding of the concepts of drug action, drug
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@handling by the body, and drug interactions will allow the dental practitioner to make proper
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@judgments and grasp the concepts relevant to new drug therapies on the market.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Application
REF: Role of the Dental Hygienist (Medication/Health History), Role of the Dental Hygienist (M
x @ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
edication Administration), Role of the Dental Hygienist (Emergency Situations), Role of the Dental
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
Hygienist (Nonprescription Medication) | pp. 2-3
x@ x@ OBJ: 1 x@ x@ x@ x@
TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
2. Which of the following statements is true regarding planning appointments?
x@ x@ x@ x@ x@ x@ x@ x@ x@
a. Whether or not patients are taking medication for systemic diseases is o
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
f little x@
consequence in the dental office. x@ x@ x@ x@
b. Asthmatic patients should have dental appointments in the morning.
x@ x@ x@ x@ x@ x@ x@ x@
c. Diabetic patients usually have fewer problems with a morning appointme
x@ x@ x@ x@ x@ x@ x@ x@ x@
nt compared with afternoon appointments.
x@ x@ x@ x@
d. Both B and C are true. x@ x@ x@ x@ x@
ANS: x @ D
Asthmatic patients who experience dental anxiety should schedule their appointments when the
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
y are not rushed or under pressure early in the morning. Diabetic patients usually have relativ
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ely fewer problems with a morning appointment. Patients taking medication for systemic diseas
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
es may require special handling in the dental office.
x@ x@ x@ x@ x@ x@ x@ x@
DIF: Comprehension
REF: Role of the Dental Hygienist (Appointment Scheduling)
x @ x@ x@ x@ x@ x@ x@
| p. 3 OBJ: 1
x@ x@ x@TOP: NBDHE, 6.0. Pharmacology
x@ x @ x @ x@ x@
,3. Nutritional or herbal supplements x@ x@ x@
a. carry the U.S. Food and Drug Administration (FDA) approval for disease
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
states.
b. are not drugs. x@ x@
c. can cause adverse effects.
x@ x@ x@
d. will not interact with other drugs the patient may be taking.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ANS: x @ C
Nutritional or herbal supplements are quite capable of causing adverse effects. The majority of n
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
utritional or herbal supplements do not carry FDA approval for treating disease states. These su
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
pplements are drugs and can cause adverse effects and interact with different drugs.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Comprehension
REF: Role of the Dental Hygienist (Nutritional or Herbal Supplements
x @ x@ x@ x@ x@ x@ x@ x@ x@
) | p. 3 OBJ: 1 TOP: NBDHE, 6.0. Pharmacology
x@ x@ x@ x@ x @ x @ x@ x@
4. Which type of drug name usually begins with a lowercase letter?
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
a. Brand name x@
b. Code name x@
c. Generic name x@
d. Trade name x@
ANS: x @ C
Before any drug is marketed, it is given a generic name that becomes the ―official‖ name of t
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
he drug. Each drug is assigned only one generic name selected by the U.S. Adopted Name C
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ouncil, and the name is not capitalized. The brand name is equivalent to the trade name and i
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
s capitalized. Although the brand name is technically the name of the company marketing the
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
product, this term is often used interchangeably with the trade name. The code name is the in
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
itial term used within a pharmaceutical company to refer to a drug while it is undergoing inv
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
estigation and is often a combination of capital letters and numbers, the letters representing an
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
x@abbreviation of the company name. x@ x@ x@ x@
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
x @ x@ x@ x@ x@ x@ x @
TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
5. A drug’s generic name is selected by the
x@ x@ x@ x@ x@ x@ x@
a. pharmaceutical company manufacturing i x@ x@ x@
t.
b. Food and Drug Administration (FDA).
x@ x@ x@ x@
c. U.S. Adopted Name Council.x@ x@ x@
d. Federal Patent Office. x@ x@
ANS: x @ C
Each drug is assigned only one generic name (e.g., ibuprofen). It is selected by the U.S. Ado
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
pted Name Council. The generic name is not selected by the FDA or the Federal Patent Offic
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
e. The pharmaceutical company manufacturing the drug clearly has an influence on the generic
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@name given its drug, but the final decision is not the company’s.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Recall REF: Drug Names | p. 4 x @ x@ x@ x@ x@
OBJ: 3 TOP: NBDHE, 6.0. Pharmacology
x @ x@ x @ x@ x@
6. Which of the following is true concerning generic and trade names of drugs?
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
a. A drug may only have one generic name and one trade
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
name.
, b. A drug may only have one generic name, but it may have several trade
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
names. @
c. A drug may have several generic names, but it may only have one trade
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
name. x@
d. A drug may have several generic names and several trade names.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ANS: x @ B
Each drug has only one generic name but may have several trade names. For each drug, there
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
is only one generic name. It is not capitalized, and it becomes the ―official‖ name of the dru
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
g. The pharmaceutical company discovering the drug gives the drug a trade name. The trade n
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ame is protected by the Federal Patent Law for 20 years from the earliest claimed filing date,
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
plus patent term extensions. Although the brand name is technically the name of the company
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
marketing the product, it is often used interchangeably with the trade name.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
x @ x@ x@ x@ x@ x@ x @
TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
7. Two drugs that are found to be chemically equivalent, but not biologically equiva
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
lent or therapeutically equivalent are said to differ in
x@ x@ x@ x@ x@ x@ x@ x@
a. potency.
b. efficacy.
c. bioavailability.
d. therapeutic index. x@
ANS: x @ C
A preparation can be chemically equivalent yet not biologically or therapeutically equivalent.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
These products are said to differ in their bioavailability. The potency of a drug is a function o
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
f the amount of drug required to produce an effect. The efficacy is the maximum intensity of
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@effect or response that can be produced by a drug. The therapeutic index is the ratio of the l
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ethal dose for 50% of the experimental animals divided by the effective dose for 50% of the
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
experimental animals. If the value of the therapeutic index is small, toxicity is more likely.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Recall
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
x @ x@ x@ x@ x@ x@ x@ x@ x @
4 TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
8. How many years must pass after a drug patent expires before other drug companies can ma
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
rket the same compound as a generic drug?
x@ x@ x@ x@ x@ x@ x@
a. 20 years x@
b. 17 years x@
c. 7 years x@
d. 0 years x@
ANS: x @ D
Once a drug patent expires, competing companies may immediately market the same compoun
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
d in generic form. The pharmaceutical company discovering the drug gives the drug a trade n
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ame. The trade name is protected by the Federal Patent Law for 20 years from the earliest cla
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
imed filing date, plus the patent term extensions.
x@ x@ x@ x@ x@ x@ x@
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
x @ x@ x@ x@ x@ x@ x@ x@ x @
4 TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
x@ x@ x@ x@ x@ x@ x@
Edition by Elena Bablenis Haveles
x@ x@ x@ x@
Complete Test Bank
x@ x@
,Chapter 01: Information Sources, Regulatory Agencies, Drug Legislation, and Prescription
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
Writing
Haveles: Applied Pharmacology for the Dental Hygienist, 9th Edition
x@ x@ x@ x@ x@ x@ x@ x@
MULTIPLE CHOICE x@
1. Knowledge of pharmacology aids the dental professional in
x@ x@ x@ x@ x@ x@ x@
a. obtaining a patient’s health history. x@ x@ x@ x@
b. administering drugs in the office. x@ x@ x@ x@
c. handling emergency situations. x@ x@
d. selection of a nonprescription medicatio x@ x@ x@ x@
n.
e. All of the above. x@ x@ x@
ANS: x @ E
All of the choices are true. Because many of our patients are being treated with drugs, knowl
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
edge of pharmacology helps in understanding and interpreting patients’ responses to health hist
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ory questions. Knowledge of the therapeutic and adverse effects of medications obviously help
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
s in their proper administration in the office. Emergency situations may be caused by drugs o
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
r treated by drugs; thus, knowledge of pharmacology is of great help, especially because a rap
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
id response is sometimes required. A clear understanding of the concepts of drug action, drug
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@handling by the body, and drug interactions will allow the dental practitioner to make proper
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@judgments and grasp the concepts relevant to new drug therapies on the market.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Application
REF: Role of the Dental Hygienist (Medication/Health History), Role of the Dental Hygienist (M
x @ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
edication Administration), Role of the Dental Hygienist (Emergency Situations), Role of the Dental
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
Hygienist (Nonprescription Medication) | pp. 2-3
x@ x@ OBJ: 1 x@ x@ x@ x@
TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
2. Which of the following statements is true regarding planning appointments?
x@ x@ x@ x@ x@ x@ x@ x@ x@
a. Whether or not patients are taking medication for systemic diseases is o
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
f little x@
consequence in the dental office. x@ x@ x@ x@
b. Asthmatic patients should have dental appointments in the morning.
x@ x@ x@ x@ x@ x@ x@ x@
c. Diabetic patients usually have fewer problems with a morning appointme
x@ x@ x@ x@ x@ x@ x@ x@ x@
nt compared with afternoon appointments.
x@ x@ x@ x@
d. Both B and C are true. x@ x@ x@ x@ x@
ANS: x @ D
Asthmatic patients who experience dental anxiety should schedule their appointments when the
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
y are not rushed or under pressure early in the morning. Diabetic patients usually have relativ
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ely fewer problems with a morning appointment. Patients taking medication for systemic diseas
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
es may require special handling in the dental office.
x@ x@ x@ x@ x@ x@ x@ x@
DIF: Comprehension
REF: Role of the Dental Hygienist (Appointment Scheduling)
x @ x@ x@ x@ x@ x@ x@
| p. 3 OBJ: 1
x@ x@ x@TOP: NBDHE, 6.0. Pharmacology
x@ x @ x @ x@ x@
,3. Nutritional or herbal supplements x@ x@ x@
a. carry the U.S. Food and Drug Administration (FDA) approval for disease
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
states.
b. are not drugs. x@ x@
c. can cause adverse effects.
x@ x@ x@
d. will not interact with other drugs the patient may be taking.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ANS: x @ C
Nutritional or herbal supplements are quite capable of causing adverse effects. The majority of n
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
utritional or herbal supplements do not carry FDA approval for treating disease states. These su
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
pplements are drugs and can cause adverse effects and interact with different drugs.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Comprehension
REF: Role of the Dental Hygienist (Nutritional or Herbal Supplements
x @ x@ x@ x@ x@ x@ x@ x@ x@
) | p. 3 OBJ: 1 TOP: NBDHE, 6.0. Pharmacology
x@ x@ x@ x@ x @ x @ x@ x@
4. Which type of drug name usually begins with a lowercase letter?
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
a. Brand name x@
b. Code name x@
c. Generic name x@
d. Trade name x@
ANS: x @ C
Before any drug is marketed, it is given a generic name that becomes the ―official‖ name of t
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
he drug. Each drug is assigned only one generic name selected by the U.S. Adopted Name C
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ouncil, and the name is not capitalized. The brand name is equivalent to the trade name and i
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
s capitalized. Although the brand name is technically the name of the company marketing the
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
product, this term is often used interchangeably with the trade name. The code name is the in
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
itial term used within a pharmaceutical company to refer to a drug while it is undergoing inv
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
estigation and is often a combination of capital letters and numbers, the letters representing an
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
x@abbreviation of the company name. x@ x@ x@ x@
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
x @ x@ x@ x@ x@ x@ x @
TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
5. A drug’s generic name is selected by the
x@ x@ x@ x@ x@ x@ x@
a. pharmaceutical company manufacturing i x@ x@ x@
t.
b. Food and Drug Administration (FDA).
x@ x@ x@ x@
c. U.S. Adopted Name Council.x@ x@ x@
d. Federal Patent Office. x@ x@
ANS: x @ C
Each drug is assigned only one generic name (e.g., ibuprofen). It is selected by the U.S. Ado
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
pted Name Council. The generic name is not selected by the FDA or the Federal Patent Offic
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
e. The pharmaceutical company manufacturing the drug clearly has an influence on the generic
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@name given its drug, but the final decision is not the company’s.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Recall REF: Drug Names | p. 4 x @ x@ x@ x@ x@
OBJ: 3 TOP: NBDHE, 6.0. Pharmacology
x @ x@ x @ x@ x@
6. Which of the following is true concerning generic and trade names of drugs?
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
a. A drug may only have one generic name and one trade
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
name.
, b. A drug may only have one generic name, but it may have several trade
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
names. @
c. A drug may have several generic names, but it may only have one trade
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
name. x@
d. A drug may have several generic names and several trade names.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ANS: x @ B
Each drug has only one generic name but may have several trade names. For each drug, there
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
is only one generic name. It is not capitalized, and it becomes the ―official‖ name of the dru
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
g. The pharmaceutical company discovering the drug gives the drug a trade name. The trade n
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ame is protected by the Federal Patent Law for 20 years from the earliest claimed filing date,
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
plus patent term extensions. Although the brand name is technically the name of the company
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
marketing the product, it is often used interchangeably with the trade name.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
x @ x@ x@ x@ x@ x@ x @
TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
7. Two drugs that are found to be chemically equivalent, but not biologically equiva
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
lent or therapeutically equivalent are said to differ in
x@ x@ x@ x@ x@ x@ x@ x@
a. potency.
b. efficacy.
c. bioavailability.
d. therapeutic index. x@
ANS: x @ C
A preparation can be chemically equivalent yet not biologically or therapeutically equivalent.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
These products are said to differ in their bioavailability. The potency of a drug is a function o
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
f the amount of drug required to produce an effect. The efficacy is the maximum intensity of
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x
@effect or response that can be produced by a drug. The therapeutic index is the ratio of the l
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ethal dose for 50% of the experimental animals divided by the effective dose for 50% of the
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
experimental animals. If the value of the therapeutic index is small, toxicity is more likely.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
DIF: Recall
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
x @ x@ x@ x@ x@ x@ x@ x@ x @
4 TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@
8. How many years must pass after a drug patent expires before other drug companies can ma
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
rket the same compound as a generic drug?
x@ x@ x@ x@ x@ x@ x@
a. 20 years x@
b. 17 years x@
c. 7 years x@
d. 0 years x@
ANS: x @ D
Once a drug patent expires, competing companies may immediately market the same compoun
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
d in generic form. The pharmaceutical company discovering the drug gives the drug a trade n
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ame. The trade name is protected by the Federal Patent Law for 20 years from the earliest cla
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
imed filing date, plus the patent term extensions.
x@ x@ x@ x@ x@ x@ x@
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
x @ x@ x@ x@ x@ x@ x@ x@ x @
4 TOP: NBDHE, 6.0. Pharmacology
x @ x@ x@