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Summary Biochemistry

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Summary of 2 pages for the course Biochemistry at CCEA (Biochemistry notes)

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Biochemistry
The Chemicals of Life

 Micronutrients – small, inorganic molecules /atoms
 Macromolecules – large, organic molecules, all containing a chain of carbon atoms with attached hydrogen and
oxygen atoms.

There are four groups of macromolecules:

 Carbohydrates
 Proteins
 Lipids
 Nucleic acids

All four groups contain Carbon, Hydrogen and Oxygen while protein and nucleic acids contain nitrogen and sulfur.

Molecule shape is important for:

 Molecules reacting together
 Recognition

The same molecule in different shapes – isomers

Many macromolecules are polymers and are made up of subunits called monomers.

Within groups the bonds that bind subunits are called:

 Glycosidic – links in starch and cellulose
 Peptide – links in proteins
 Ester – links in lipids

Within all organic molecules, a variety of bonding is possible

 Most of the bonding within macromolecules is covalent
 When mineral elements join on they do so ionically. Also, hydrogen can behave as an ion so ionic bonding can
occur within certain molecules; especially proteins which are formed when amino acids join together

Hydrogen Bonds

In many molecules, the electrons tend to congregate more at one or two regions of the molecule. This gives that
region of the molecule a relatively negative charge, while the opposite end is more positive.

These molecules are described as being polar

While many polar molecules are close together attractions form between the relative +ve bit of one molecule and
the relatively -ve bit of another.

Individually these electrostatic attractions are quite weak, but collectively large numbers of them can be strong

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