NR 503 Week 4 Midterm Exam

Question 1 Which of the following statements best describe efficacy? • It is an estimate of the benefit of treatment under ideal conditions • It is an estimate of the reduction of disease in treated groups Question 2 A study is conducted for a pharmaceutical agent that has shown promise for reducing heart disease among women. In order to more fully test the agent, an additional study is done restricting the participants to be r&omized to those who have a history of hypertension. Which of the following advantages cannot be claimed by the researchers? • The generalizability of the study is increased Question 3 What is the main advantage of the r&omization of the 168 study participants to one of the two drug treatment groups? • Reduces the potential for selection bias in allocation of treatment group Question 4 After entry into the study, patients were first classified into three groups, those who had a previous AMI, those with a first AMI who were at high risk for other cardiovascular diseases such as congestive heart failure, & those with a first AMI who were at low risk for other cardiovascular diseases. Which term best describes the study design? • R&omized clinical trial with stratified r&omization Question 5 After assignment to treatment group, 77% of those in the placebo group were men, while 80% of those in the drug X group were men. Which statement is most likely to be true? • R&omization was successful since the investigators did not alter the selection of participants in either group in order to ensure equal percentages of men Question 6 A preliminary analysis was conducted after 6 months & found that 87% of participants in the placebo group & 85% of those in the drug X group had taken more than 90% of their prescribed dosages. Which statement best describes this finding?