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Summary Outline of notes looking at the genetic factors of aggression

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An informative document with facts and figures about genetic factors in aggression. This includes looking at the research done through twin and adoption studies as well as the influence of the MAOA gene. Looks into the effect of nature and nurture as well as the gene environment interactions

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Aggression 2
Genetic factors
15-01-21

Twins studies
 Have suggested about 50% of the variance for aggression is inherited
 Coccaro et al (1997)
o Studied male MZ (identical) and DZ (non-identical) twins
o Found a 50% concordance rate in MZ twins
o Only has a 19% concordance rate in DZ twins
o When looking at verbal aggression it was 20% for MZ and 7% for DZ

Adoption studies
 Rhee and Waldman (2002)
o Carried out a meta-analysis of adoption studies of direct aggressions
and antisocial behaviour
o Found that genetic influences accounted for 41% of the variance in
aggression
o This is in line with the findings from other studies

MAOA Gene
 Monomine oxidase A is an enzyme
 Mops up the neurotransmitters in the brain after a nerve impulse has been
transmitted
 Breaks down the neurotransmitters into chemicals that can be recycled in the
body
 A dysfunction may lead to abnormal activity of the MAOA enzyme
o This impacts serotonin levels in the brain
 Also named the warrior gene
 Brunner et al (1993)
o Studied 28 male members of a large Dutch family
o This family was involved in impulsively aggressive violent crimes like rape
o Found that the men had abnormally low levels of MAOA in their
brains
o Also low activity of the MAOA gene
 Stuart et al (2014)
o Studied 97 men
o They had all been involved in inflicting intimate partner violence
o They were also all part of a batterer treatment programme
o Men with the low-activity MAOA gene were most violent

Gene-environment interactions (GxE)
 Genes are crucial influences on aggressive behaviour
 They don’t work independently however
 MAOA gene activity is only related to adult aggression when combined with
early traumatic life events
 Frazzetto et al (2007)

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September 11, 2024
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