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AQA A Level Biology - Chapter 2 Nucleic Acids - Summary Notes

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Summary notes for Chapter 2 of the AQA A Level Biology course Correspondent to the textbook NO UNNECESSARY CONTENT! Concise and Precise!

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Chapter
-
2 :
summary Notes



DNA☐ Deoxy ribonucleic acid formation -

condensation reactions

carries the bases
genetic information 1) base + sugar → nucleoside + Hit

2 chains ( helical coiled) 2) nucleotide + phosphate Purines are
a
polymer → nucleotide HLO larger adenine
: ^
t :




⑨ double

/
↳ its monomers are
nucleotides ring guanine
Mofo nucleotide
2 72

Immotile P-mnuwoh.de
→ →
PYRIMIN dines smaller
cytosine
:
-




Phosphate

_




◦ thymine
µ gingering

,pµµµµgµy
jF☐É
bond
, DNA double helix


/ deoxyribose nitrogenous phosphodiester backbone
-




pentose sugar organic base

A T
}
gives stability
-




gym µ,
.




AMplimenraoy
bond It bonds between c. a
-




bases
( base pairing
↳ rule)
2- between A/T More 4G pairings

}
in


RDNA Ribonucleic acid 3- between CIG a DNA Arend makes ir more Noble




(
" "

slightly different ! interactive forces base
-



other tracking
ribose penrose sugar us deoxyribose penrose)
uracil base ( vs guanine) suited to its function ?

single chained molecule cut double) phosphodiester backbone :
protects genetic material within ( chemical ~

physical forces)
H bonds :
can be easily unzipped for replication
Semi -


conservative DNA Replication
DNA replication :
viral in cell division

Described as semi conservative because each
-
'
new
'
helix created contains 1 strand from the helix from which it was copied

1 only me 2
enzyme ,
/
① @ origin ③


/
,
DNA helicase causes 2 strands to split DNA
polymerase joins the tree nucleotides together to join the 2 strands

↳ ↳


¥ ¥1
breaks H bonds between them wearing phosphodiester bonds wondersatin)
nai case

↓ .




② 2 strands unravel ,
leaving bars exposed

¥:÷i÷¥

tree nucleotides bind row rhplimenrary bases all nucleotides join row Mplimenrary balls

DNA lipase forges H bonds between complimentary bases



proof of semi -


conservative replication
Tiperimenral evidence
HMEÉN /aÑmd→ newly
conserve built strand


bases

are
nitrogenous

when bacteria nitrogen from the medium they grow
grow they take
up
⑧ The DNA is extracted then placed in a special solution



/
, ,




of nitrogen 14N ( lighter) 15N ( heavier )

2 ↳ to be spun
isotopes

heavier sediments appear lower down in tube


centrifuge
:




process Geno bent ten 2

② Ñatteria ③ ÑÑ bacteria transferred "
④ bent bacteria
"'
① bacteria grown in N medium grown in 15N to N medium placed in 19N

⑤ ⑤
"N

② G-
all
'"
N Mix
an * µ mix
[control ]

disproves conservative model ↳ disproves dispersive model because

% ntervative model :
original helix served as template for new one ↳ mix is created full 14N and mix is created

Old
dispersive model : hybrid / each strand contains new ^




C0NTlND

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