Principles Of Biochemistry
8th Edition By David L.
Nelson; Michael M. Cox All
Chapters 1-28 LATES
The Test Bank for Lehninger Principles of Biochemistry, 8th Edition by David
L. Nelson & Michael M. Cox provides complete coverage of all 28 chapters,
bringing the full scope of the textbook together in one comprehensive study
resource.
Organized chapter by chapter, it covers the major principles of
biochemistry, including biomolecules, protein structure and function,
enzymes, metabolism, bioenergetics, molecular biology, and related
biochemical pathways. The complete structure supports systematic review,
concept reinforcement, and exam preparation across the entire course.
With Chapters 1–28 fully covered, this resource is designed for efficient
chapter-by-chapter study, self-assessment, and comprehensive biochemistry
exam preparation.
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, 1. A dynamic steady state results when
A) A molecule stops being degraded.
B) An organism is at equilibrium with its surroundings.
C) There is no net energy transfer.
D) The rate of intake or synthesis of a molecule equals the rate of its disappearance.
ANSWER: C
2. If a chemical reaction starts with 1 M concentrations each of reactants A and B and
products C and D, under what conditions of K′eq and ΔG′° will the reaction proceed in
the forward direction (ΔG′° = RT ln K′eq)?
A) If K′eq is greater than 1 and ΔG′° is negative.
B) If K′eq is 0 and ΔG′° is negative.
C) If K′eq is negative and ΔG′° is negative.
D) If K′eq is less than 1 and ΔG′° is positive.
ANSWER: A
3. Living cells and organisms
A) Exchange energy but not matter with their surroundings.
B) Exchange energy and material with their surroundings.
C) Are closed systems.
D) Are at equilibrium with their surroundings.
ANSWER: B
4. The standard free-energy changes of two sequential chemical reactions are additive
only if
A) The reactions share a common intermediate.
B) Each reaction has a negative ΔG′°.
C) The overall (net) reaction has a positive ΔG′°.
D) The exergonic reaction occurs first.
ANSWER: A
5. Which of the following has a thioester bond?
A) PEP (phosphoenolpyruvate)
B) ATP
C) Phosphocreatine
D) Acetyl-CoA
ANSWER: D
6. What provides the energy for the synthesis in an RNA polymer?
A) The transfer of an energy-rich ribonucleoside monophosphate to the polymer.
B) The hydrolysis of two anhydride bonds in ribonucleoside triphosphates.
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,C) The transfer of the γ phosphate of a ribonucleoside triphosphate to the polymer.
D) The transfer of an energy-rich ribonucleoside triphosphate to the polymer.
ANSWER: B
7. When a nucleophile attacks the α phosphorous atom of ATP, what kind of transfer
occurs?
A) Pyrophosphoryl transfer
B) Phosphoryl transfer
C) Adenylyl transfer
D) Adenosine transfer
ANSWER: C
8. When dNTPs become depleted in the cell, which of the following enzymes will
regenerate dNTPs from dNDPs?
A) Nucleoside diphosphate kinase
B) Polyphosphate kinase
C) Creatine kinase
D) Adenylate kinase
ANSWER: A
9. Which of the following enzymes can catalyze the conversion of AMP to ADP?
A) Nucleoside diphosphate kinase
B) Polyphosphate kinase
C) Creatine kinase
D) Adenylate kinase
ANSWER: D
10. Conversion of NAD+ to NADH is accomplished by the addition of
A) A proton
B) An electron
C) A hydride ion
D) A hydrogen atom.
ANSWER: C
11. Which of the following carbon-containing molecules is most fully oxidized?
A) Carbon monoxide
B) Carbon dioxide
C) Methane
D) Ethanol
ANSWER: B
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, 12. The oxidation-reduction reaction Fe2+ + Cu2+ ↔ Fe3+ + Cu+, can be described in
terms of two half-reactions:
(1) Fe2+ ↔ Fe3+ + e−
(2) Cu2+ + e− ↔ Cu+
Which of the following statements is true?
A) In the overall reaction at the top, the cupric ion (Cu2+) is the reducing agent.
B) In half-reaction (2), cupric ion (Cu2+) is being oxidized.
C) In half-reaction (1), Fe3+ and e− constitute a conjugate redox pair.
D) In the overall reaction at the top, the ferrous ion (Fe2+) is oxidized by the cupric ion
(Cu2+).
ANSWER: D
13. Electrons can be transferred from one molecule (electron donor) to another molecule
(electron acceptor) by all of the following ways except
A) As a hydride ion
B) Directly as an electron
C) As a proton
D) As a hydrogen atom.
ANSWER: C
14. Which of the following is true of flavin nucleotides?
A) They have no reduction potential unless bound to a protein.
B) They always accept two electrons.
C) They are utilized by oxygenases.
D) They act as prosthetic groups.
ANSWER: D
15. Below are the standard reduction potentials (E′°) for two conjugate redox pairs:
Pyruvate/lactate E′° = −0.185 V
NAD+/NADH E′° = −0.320 V
Which of the following is true?
A) The pyruvate/lactate conjugate redox pair has a greater tendency to lose electrons than the
NAD+/NADH redox pair.
B) Pyruvate has a greater affinity for electrons than NAD+.
C) NAD+ is a reducing agent.
D) Under standard conditions, NAD+ is more likely to be converted to NADH than pyruvate
is to be converted to lactate.
ANSWER: B
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