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Summary AQA Paper 1 Biology - Section 3.1.5: Nucleic acids are important information-carrying molecules

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This is a Word document that includes all my summary notes for AQA Paper 1 Biology - Section 3.1.5: Nucleic acids are important information-carrying molecules It is formatted with two columns, including diagrams

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DNA
Structure of DNA : In DNA specifically, the pentose sugar
in the nucleotide is deoxyribose
: DNA = Deoxyribonucleic Acid
: The nitrogen-containing base, in DNA,
can be one of four different types
: codes for the sequence of amino
: adenine, cytosine, guanine,
acids in the primary structure of a
thymine
protein
- A, C, G or T
- determines the final unique 3D
structure of the tertiary protein

– determines the structure and : The pentose sugar and phosphate
function of the protein groups form a sugar-phosphate
backbone

- very strong due to the strong
: directly determines the structure and
covalent phosphodiester bonds
function of proteins which in turn
between them that hold the polymer
determine your characteristics
together


: a polymer that is twisted into a
double helix structure

: The monomer of DNA is the
nucleotide



: A nucleotide, in general, is made up of : formed by a condensation reaction of
a pentose sugar attached to a the nucleotide monomers
nitrogenous base, and a phosphate
group : The phosphodiester bond forms
between a deoxyribose on one
nucleotide and a phosphate on an
adjacent nucleotide

- catalysed by DNA polymerase

- incredibly strong covalent bonds,

- always stays in its shape and correct
sequence, so the genetic code does
not break down

: The phosphodiester bonds are formed
between the deoxyribose (pentose)
sugar and the phosphate group

, : Between the sugar and the base is a : The hydrogen bonds are relatively
glycosidic bond weak allowing DNA helicase to easily

: Between the sugar and the - break the hydrogen bonds to easily
phosphate is an ester bond unwind the two strands of the
double helix to allow for replication
: Two polynucleotide strands are held
together by hydrogen bonds between
the bases
: DNA is a large molecule, so it can
- forming 2 strands next to each other carry a lot of information

- allows DNA to form a double helix - stable due to the presence of strong
structure as the two chains twist phosphodiester bonds in the sugar-
phosphate backbone

: The two polynucleotide DNA strands
are antiparallel, they run in opposite
directions to each other

- One strand is 3’ to 5’ and the other
strand is 5’ to 3’




: Hydrogen bonds can only form
between complementary base pairs

: cytosine can only form hydrogen : Because of this complementary base
bonds with guanine (C-G) pairing, in a DNA molecule there will
: adenine can only form hydrogen always be an equal number of A and
bonds with thymine (A-T) T, and an equal number A and T

–complementary base pairing



: Adenine forms 2 H-bonds with
Thymine

: Cytosine forms 3 hydrogen bonds
with Guanine



: important to help maintain the order
of the genetic code when DNA
replicates

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