ADVANCED PHARMACOLOGY
FINAL EXAM REVIEW NEWEST
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Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy?
----Solution----
To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate?
----Solution----
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a
low TSH level with?
----Solution----
Propanolol (Inderal)
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Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
----Solution----
Aldosterone antagonist
Heparin exerts its therapeutic action by what?
----Solution----
Upregulating the activity of one of the body's natural anticoagulant
molecules, antithrombin III
What physiologic action happens when the offending drug is
administered during an anaphylactic reaction.
----Solution----
Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
----Solution----
Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension?
----Solution----
Thiazide diuretics
What is the effect of cardiac glycosides?
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----Solution----
Digitalis glycosides have a negative chronotropic effect on the cardiac
muscle cells.
Amenorrhea is the most common side effect of which birth control
medication?
----Solution----
Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for
available beta-receptor sites?
----Solution----
Atenolol (Tenormin)
What type of action does nitrates have on the body?
----Solution----
Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol
(LDL) for patients with known coronary artery disease?
----Solution----
100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs?