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LESSON 1: Cell Regulation and
Cancer Cells
Created @May 15, 2025 11:58 AM
Tags
CELL CYCLE REGULATION
WHAT IS CELL REGULATION?
Cell cycle regulation refers to the control mechanisms that determine whether
cells will divide, remain dormant, at rest, or undergo programmed cell death. It
plays a crucial role in normal tissue repair and regeneration, and its disruption
is a key feature of cancer.
LESSON 1: Cell Regulation and Cancer Cells 1
, FACTORS THAT REGULATE CELL DIVISION
EXTERNAL FACTOR
Physical External Factor
Chemical External Factor
INTERNAL FACTOR
Kinesis
Cyclin
EXTERNAL FACTORS
Physical External Factor: (cell-to-cell contact)
Contact Inhibition - When a cell touches another cell, it stops dividing.
Anchorage Dependent - Cells only grow if surface is available and stop
dividing when detached from the culture dish.
Chemical External Factor: (Growth Factor)
Chemical signals released by the cell, such as growth factors (proteins),
provide instructions for other cells to grow.
Proteins stimulate cell division which have the ability to activate specific
genes to trigger cell growth.
Some growth factors can also affect the growth of other cells.
e.g. Production of erythropoietin and platelets
External factors can also bind receptors that will later on trigger internal factors.
INTERNAL FACTORS.
LESSON 1: Cell Regulation and Cancer Cells 2
LESSON 1: Cell Regulation and
Cancer Cells
Created @May 15, 2025 11:58 AM
Tags
CELL CYCLE REGULATION
WHAT IS CELL REGULATION?
Cell cycle regulation refers to the control mechanisms that determine whether
cells will divide, remain dormant, at rest, or undergo programmed cell death. It
plays a crucial role in normal tissue repair and regeneration, and its disruption
is a key feature of cancer.
LESSON 1: Cell Regulation and Cancer Cells 1
, FACTORS THAT REGULATE CELL DIVISION
EXTERNAL FACTOR
Physical External Factor
Chemical External Factor
INTERNAL FACTOR
Kinesis
Cyclin
EXTERNAL FACTORS
Physical External Factor: (cell-to-cell contact)
Contact Inhibition - When a cell touches another cell, it stops dividing.
Anchorage Dependent - Cells only grow if surface is available and stop
dividing when detached from the culture dish.
Chemical External Factor: (Growth Factor)
Chemical signals released by the cell, such as growth factors (proteins),
provide instructions for other cells to grow.
Proteins stimulate cell division which have the ability to activate specific
genes to trigger cell growth.
Some growth factors can also affect the growth of other cells.
e.g. Production of erythropoietin and platelets
External factors can also bind receptors that will later on trigger internal factors.
INTERNAL FACTORS.
LESSON 1: Cell Regulation and Cancer Cells 2
