B334 OB Medications(100% Correct answers)
Anaprox (Naproxen Sodium/Aleve) correct answers- Pharmacodynamics: inhibition of the
leukotriene pathway, the prostaglandin pathway, or both blocking the chemical activity of the
COX enzymes
- Side Effects: Nausea, diarrhea, constipation, abdominal distress
- Use in Obstetrics: used to treat dysmenorrhea (painful periods) or pain during or before
menstruation
- Considerations: For all NSAIDs: Do not give if woman has hemophilia or bleeding ulcers; do
not give if woman has had an allergic or anaphylactic reaction to aspirin or another NSAID; do
not give if woman is taking anticoagulant medication
Ambien (Zolpidem) correct answers- Pharmacodynamics: acts on GABA receptors in the brain;
Short-Acting Benzodiazepine
- Side Effects: Headache, muscle pain, drowsiness, dizziness, loss of coordination, stuffy nose,
GI issues, dry mouth
- Use in Obstetrics: Hypertonic Uterine Dysfunction, Ambien used to help anxious mothers rest
and relax uterus between contractions
Atarax (Hydroxyzine) correct answers- Pharmacodynamics: reduces CNS activity and acts as an
antihistamine drug blocking H1 receptors in the brain
- Side Effects: drowsiness, dry mouth, fever, skin rash
- Use in Obstetrics: sedation, nausea and vomiting prevention, and anxiety reduction; safest
antihistamines
Betamethasone (glucocorticoids) correct answers- Pharmacodynamics: inhibition of
inflammatory and immune responses
- Side Effects: insomnia, mood changes, thinning skin, slow wound healing, nausea, stomach
pain
- Use in Obstetrics: used for women in premature labor to help accelerate fetal lung maturation
Bicitra (Sodium Citrate, Citric acid) correct answers- Pharmacodynamics: reduces gastric acidity
- Side Effects: diarrhea, nausea vomiting, stomach pain, fluid retention, muscle pain
- Use in Obstetrics: general anesthesia for emergent C-section to reduce gastric acidity (used to
avoid acidic aspiration during general anesthesia)
Calcium Gluconate correct answers- Pharmacodynamics: prevents/ treats calcium deficiencies
- Side Effects: nausea, vomiting, decreased appetite, constipation, increased thirst
- Use in Obstetrics: preeclampsia, magnesium sulfate toxicity, hypocalcemia (reverse toxicity of
magnesium sulfate)
Cervadil (dinoprostone) correct answers- Pharmacodynamics: stimulates uterine contraction
causing expulsion of uterine contents; dilate cervix
- Side Effects: diarrhea, nausea, vomiting, fever, uterine rupture
- Use in Obstetrics: to expel uterine contents in fetal death or missed abortion during second
trimester, or to efface and dilate the cervix in pregnancy at term.
Anaprox (Naproxen Sodium/Aleve) correct answers- Pharmacodynamics: inhibition of the
leukotriene pathway, the prostaglandin pathway, or both blocking the chemical activity of the
COX enzymes
- Side Effects: Nausea, diarrhea, constipation, abdominal distress
- Use in Obstetrics: used to treat dysmenorrhea (painful periods) or pain during or before
menstruation
- Considerations: For all NSAIDs: Do not give if woman has hemophilia or bleeding ulcers; do
not give if woman has had an allergic or anaphylactic reaction to aspirin or another NSAID; do
not give if woman is taking anticoagulant medication
Ambien (Zolpidem) correct answers- Pharmacodynamics: acts on GABA receptors in the brain;
Short-Acting Benzodiazepine
- Side Effects: Headache, muscle pain, drowsiness, dizziness, loss of coordination, stuffy nose,
GI issues, dry mouth
- Use in Obstetrics: Hypertonic Uterine Dysfunction, Ambien used to help anxious mothers rest
and relax uterus between contractions
Atarax (Hydroxyzine) correct answers- Pharmacodynamics: reduces CNS activity and acts as an
antihistamine drug blocking H1 receptors in the brain
- Side Effects: drowsiness, dry mouth, fever, skin rash
- Use in Obstetrics: sedation, nausea and vomiting prevention, and anxiety reduction; safest
antihistamines
Betamethasone (glucocorticoids) correct answers- Pharmacodynamics: inhibition of
inflammatory and immune responses
- Side Effects: insomnia, mood changes, thinning skin, slow wound healing, nausea, stomach
pain
- Use in Obstetrics: used for women in premature labor to help accelerate fetal lung maturation
Bicitra (Sodium Citrate, Citric acid) correct answers- Pharmacodynamics: reduces gastric acidity
- Side Effects: diarrhea, nausea vomiting, stomach pain, fluid retention, muscle pain
- Use in Obstetrics: general anesthesia for emergent C-section to reduce gastric acidity (used to
avoid acidic aspiration during general anesthesia)
Calcium Gluconate correct answers- Pharmacodynamics: prevents/ treats calcium deficiencies
- Side Effects: nausea, vomiting, decreased appetite, constipation, increased thirst
- Use in Obstetrics: preeclampsia, magnesium sulfate toxicity, hypocalcemia (reverse toxicity of
magnesium sulfate)
Cervadil (dinoprostone) correct answers- Pharmacodynamics: stimulates uterine contraction
causing expulsion of uterine contents; dilate cervix
- Side Effects: diarrhea, nausea, vomiting, fever, uterine rupture
- Use in Obstetrics: to expel uterine contents in fetal death or missed abortion during second
trimester, or to efface and dilate the cervix in pregnancy at term.
