what prophylaxis is recommended for HIV patients to prevent opportunistic infections if CD4<50?
- Answers PJP, toxoplasmosis, and MAC
what opportunistic infections are HIV pts at risk for when CD4<200? - Answers oropharyngeal
candidiasis and PJP
what opportunistic infections are HIV pts at risk for when CD4<100? - Answers toxoplasmosis
encephalitis and cryptococcal meningitis
what opportunistic infections are HIV pts at risk for when CD4<50? - Answers MAC and CMV
treatment options for hepC non-cirrhotic - Answers gelcaprevir/pibrentasvir OR
sofosbuvir/velpatasvir
treatment options for hepC compensated cirrhosis (Child Pugh B) - Answers
gelcaprevir/pibrentasvir (all genotypes) OR
sofosbuvir/velpatasvir (all genotypes except 3)
treatment options for hepC decompensated cirrhosis (Child Pugh C) - Answers
ledispavir/sofosbuvir/ribavirin (all genotypes except 2 and 3)
sofosbuvir/velpatasvir/ribivirin (all genotypes)
the NS5A class of hepC drugs (-asvir) have drug interactions with which common drug class -
Answers PPIs
-cannot use velpatasvir
-can use ledipasvir up to 20mg of omeprazole
-can use elbasvir
side effects of linezolid - Answers bone marrow suppression
neuropathies
serotonin syndrome
lactic acidosis
hepatotoxicity
side effects of telavancin - Answers nephrotoxicity
, NIOSH drug (adverse reproductive effects)
infusion related reactions
QT prolongation
side effects of ceftaroline - Answers hematologic (anemia, leukopenia/neutropenia)
rash
GI
measurement if antibiotic exposure - Answers days of therapy
measurement of antibiotic consumption - Answers defined daily dose
indications for antibiotics to treat acute otitis media (AOM) - Answers pain for >48 hrs
otorrhea
if 6 mon to <2 years with bilateral
fever >/=39 degrees
acute bacterial sinusitis (acute) - Answers 4 weeks
acute bacterial sinusitis (subacute) - Answers 1 month to 3 months
acute bacterial sinusitis (chronic) - Answers >3 months
when is imaging recommended in diagnosing acute bacterial rhinosinusitis - Answers -
immunocompromised patients
-orbital or intracranial involvment
does IDSA support watchful waiting in acute bacterial sinusitis? - Answers no
major feature of acute bacterial sinusitis - Answers purulent nasal discharge and fever lasting
72-96hrs
main pathogens that cause acute bacterial sinusitis - Answers strep pneumo
H. influenza
Moraxella catarhalis
staph aureus
which patients should be getting high dose augmentin (2g BID) for acute bacterial sinusitis? -
Answers -severe infection (fever and/or systemic signs)