Comprehensive Questions with
Verified Answers Graded A+
1. Homophilic Interactions Answer: Interactions between two of the same receptors
2. Heterophilic Interactions Answer: Interactions between two ditterent receptors
3. Leukocyte Rolling Answer: A process mediated by selectins which lead to integrin
activation in a blood vessel to recruit immune cells to the site of infection
4. IgSF Answer: Cell-cell adhesion proteins that interact with integrins
5. Plasmodesmata Answer: Cell-cell junctions in plants
6. Focal Adhesion Answer: Cell-ECM adhesion
7. Hemidesmosome Answer: Cell-basal lamina adhesion
8. Adherens Junction Answer: Cell-cell adhesion with continuous zones of attachment
9. Desmosome Answer: cell-cell adhesion with localized points of attachment
10. Adhesive junctions Answer: Junctions formed by cadherins protruding from the cell
11. β-catenin Answer: A protein that binds to the cytoplasmic tail of a cadherin
12. α-catenin Answer: A protein that recruits actin to an adherens junction
13. Desmocollin and Desmoglein Answer: Desmosomal cadherins
14. Desmosome core Answer: the extracellular space between two cells connected by a
desmosome
15. Claudins Answer: Proteins with large extracellular loops that form ion selective pores and
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, interlock to create a tight seal
16. Occludins Answer: Large looped transmembrane proteins involved in tight junctions
17. Junctional Adhesion Moleucles Answer: Globular transmembrane proteins
involved in tight junctions
18. Proteoglycans Answer: Protein-polysaccharide complexes that provide structure to the
extracellular matrix
19. Fibronectin Answer: An adhesive glycoprotein that helps the cell attach to the extracellula
matrix.
20. Laminin Answer: An adhesive glycoprotein that forms lamina
21. Collagen Answer: An abundant ECM protein that forms fibers with high tensile strength
22. Procollagen Answer: The precursor of collagen formed by a triple helix of α chains
23. Procollagen peptidase Answer: An enzyme responsible for cleaving the terminal end
of the collagen precursor
24. Elastin Answer: Fibers in the ECM rich in glycine and proline with crosslinked lysine bonds
25. Glycosaminoglycans (GAGs) Answer: Carbohydrates with repeating disaccharide
units that form hydrophillic gels with proteins to hold water and provide rigidity
26. Chondroitin sulfate, keratan sulfate, and hyaluronate Answer:
Common GAGs
27. Basal Lamina Answer: A thin sheet of specialized ECM underlying epithelial cells and
providing structural support and a barrier to permeability
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