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MRI Physics & MRI notes

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This is notes for MRI & MRI physics.

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December 17, 2025
Number of pages
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Written in
2025/2026
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mi basics 9125

, URI is variable
/configurable/flexible
noisy
based statistics
analysis on> >

modes options/alternatives
many
3 tissues

wm =>
myelinatedthan
axons
csf => clear fluid in ventricles
,
GM on T1
lighter cisterns , subara
GM darker TelFLAR
.


on
space

darhypnte
6m = neuronal cell bodies , dendrites , synapses T1-

context deep thalamus T2f
darker
nuclei
(bg ,

on T1
lighter on T2

now uRI works Heb
X
·

body has lots of H atoms
(mainly in water) ,
these It nuclei
-

like protons
act
tiny magnets
inside
strong external magnetic field (Bo), many of these
·
a

protons align either with or against the field
·
an RF pulse is applied at the "larmor frequency", which
tips the alignment from the magnetic field
proton away
this moves them into
high-energy , unstable state
after the RF pulse stops, protons return to their
original
·




alignment via 2 main processes :
the time it takes protons to
Te relaxation llongitudinal) realign with the me
T2 relaxation (transverse) >
=


the time it takes for their spins
to de-phase close coherence)
as protons relax
they emit RF
signals which are picked up
·
,

bydetectors

gradient magnetic fields, the MRI encodes spatial
using system
·




information so that the signals can be reconstructed into
which location
an
image (which noxel correspones to


·




by selecting specific timings (TE : echo time, TR : repetition time) ,
different tissue types will appeardifferently


variation contrast btw soft
pros=> ionizing
no , excellent
tissue , versatile
cons => expensive , sensitive to motion ,
relatively flow

, Sep 8 , 2025
after RF pulse
signalsdecaying lecture I
3 main quantities
(1) density of water + feet) proton density
(2) Te relaxation time to
=> sensitive D
tissue
(3) Te relaxation time type
tissue types
· molecular tumbling
Speed
cortical surfaces + thickness





subcortical structure+
Snape
localM
changes
structural URL does bone from air
4 . not
distinguith
limitations : 5. Subcortical areas - poor contrast
direct measure 6 miss certain
.
1 no .

single sequence may
2 .
Not quantitative things completely
artefacts noise
.
3 Tele values vary within GM/WM 7 +

Contrast manipulated by URL Sequence timing




Th weighting
M < Th COF
[H+]
weighting Th
weighting
WM < To T2 WM( Te Gu << Te CSF

short repetition timeCTR) long TR
long TR
Short echo time (TE) Short TE
long TE
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