Family & Adult NP Dermatology Clinical
Review Test Bank – 150 Questions ,
Answers And Rationale 2025/2026
1. A 22-year-old presents with erythematous papules and pustules
on the face, sparing the nasolabial folds. What is the most likely
diagnosis?
Rosacea
Rosacea typically presents with central facial involvement,
flushing, papules, and pustules while sparing the nasolabial
folds.
2. Which pathogen most commonly causes impetigo?
Staphylococcus aureus
S. aureus is the most common cause of impetigo, especially the
non-bullous type.
3. A scaling, well-demarcated patch on the scalp with broken hairs is
most consistent with:
Tinea capitis
Tinea capitis causes alopecia with scaling and “black dot” hairs
from fungal infection.
4. First-line treatment for mild comedonal acne:
Topical retinoid
Topical retinoids normalize follicular keratinization and are first-
line for comedonal acne.
5. A target lesion with three concentric color zones is characteristic
of:
Erythema multiforme
, Target lesions are pathognomonic for erythema multiforme,
often triggered by HSV.
6. A 63-year-old with a pearly papule and telangiectasias likely has:
Basal cell carcinoma
BCC presents as a pearly, translucent papule with rolled borders
and telangiectasias.
7. Which skin cancer is most associated with rapid growth and
metastasis?
Melanoma
Melanoma has the highest metastatic potential among skin
cancers.
8. A patient with silvery scales on extensor surfaces likely has:
Psoriasis
Psoriasis typically affects extensor areas with thick plaques and
silvery scale.
9. Treatment for cellulitis without purulence:
Cephalexin
Non-purulent cellulitis is usually caused by streptococci and
treated with a beta-lactam antibiotic.
10. A herald patch followed by a Christmas-tree rash suggests:
Pityriasis rosea
Pityriasis rosea begins with a herald patch then multiple oval
lesions along skin lines.
11. The most common cause of erysipelas:
Group A Streptococcus
Erysipelas is typically caused by Streptococcus pyogenes (GAS).
12. Actinic keratoses are considered:
Premalignant lesions
, AKs can progress to squamous cell carcinoma, making them
premalignant.
13. First-line therapy for scabies:
Permethrin 5% cream
Permethrin is the recommended primary treatment for scabies
infestation.
14. A lacy reticulated rash on the cheeks after viral illness
suggests:
Fifth disease (parvovirus B19)
Slapped-cheek appearance and lacy body rash are classic for
parvovirus B19.
15. A patient with vesicles on an erythematous base in a
dermatomal pattern has:
Herpes zoster
Zoster presents with grouped vesicles along a dermatome due to
VZV reactivation.
16. Nikolsky sign is positive in:
Pemphigus vulgaris
Pemphigus vulgaris causes intraepidermal blistering and skin
sloughing with pressure.
17. The Koebner phenomenon is associated with:
Psoriasis
Psoriasis lesions commonly appear at sites of trauma, known as
the Koebner response.
18. A child presents with honey-colored crusts around the
mouth. Diagnosis?
Impetigo
Honey-colored crusts are classic for non-bullous impetigo.
Review Test Bank – 150 Questions ,
Answers And Rationale 2025/2026
1. A 22-year-old presents with erythematous papules and pustules
on the face, sparing the nasolabial folds. What is the most likely
diagnosis?
Rosacea
Rosacea typically presents with central facial involvement,
flushing, papules, and pustules while sparing the nasolabial
folds.
2. Which pathogen most commonly causes impetigo?
Staphylococcus aureus
S. aureus is the most common cause of impetigo, especially the
non-bullous type.
3. A scaling, well-demarcated patch on the scalp with broken hairs is
most consistent with:
Tinea capitis
Tinea capitis causes alopecia with scaling and “black dot” hairs
from fungal infection.
4. First-line treatment for mild comedonal acne:
Topical retinoid
Topical retinoids normalize follicular keratinization and are first-
line for comedonal acne.
5. A target lesion with three concentric color zones is characteristic
of:
Erythema multiforme
, Target lesions are pathognomonic for erythema multiforme,
often triggered by HSV.
6. A 63-year-old with a pearly papule and telangiectasias likely has:
Basal cell carcinoma
BCC presents as a pearly, translucent papule with rolled borders
and telangiectasias.
7. Which skin cancer is most associated with rapid growth and
metastasis?
Melanoma
Melanoma has the highest metastatic potential among skin
cancers.
8. A patient with silvery scales on extensor surfaces likely has:
Psoriasis
Psoriasis typically affects extensor areas with thick plaques and
silvery scale.
9. Treatment for cellulitis without purulence:
Cephalexin
Non-purulent cellulitis is usually caused by streptococci and
treated with a beta-lactam antibiotic.
10. A herald patch followed by a Christmas-tree rash suggests:
Pityriasis rosea
Pityriasis rosea begins with a herald patch then multiple oval
lesions along skin lines.
11. The most common cause of erysipelas:
Group A Streptococcus
Erysipelas is typically caused by Streptococcus pyogenes (GAS).
12. Actinic keratoses are considered:
Premalignant lesions
, AKs can progress to squamous cell carcinoma, making them
premalignant.
13. First-line therapy for scabies:
Permethrin 5% cream
Permethrin is the recommended primary treatment for scabies
infestation.
14. A lacy reticulated rash on the cheeks after viral illness
suggests:
Fifth disease (parvovirus B19)
Slapped-cheek appearance and lacy body rash are classic for
parvovirus B19.
15. A patient with vesicles on an erythematous base in a
dermatomal pattern has:
Herpes zoster
Zoster presents with grouped vesicles along a dermatome due to
VZV reactivation.
16. Nikolsky sign is positive in:
Pemphigus vulgaris
Pemphigus vulgaris causes intraepidermal blistering and skin
sloughing with pressure.
17. The Koebner phenomenon is associated with:
Psoriasis
Psoriasis lesions commonly appear at sites of trauma, known as
the Koebner response.
18. A child presents with honey-colored crusts around the
mouth. Diagnosis?
Impetigo
Honey-colored crusts are classic for non-bullous impetigo.
