WGU D236 PATHOPHYSIOLOGY OBJECTIVE
ASSESSMENT COMPREHENSIVE EXAM 2026
◉ Which accurately describes a chromosomal alteration?
a. Turners' syndrome is a disorder in which a female has completely
or partially missing X chromosomes
b. Type 2 DM (T2DM) is caused by family history, behavior,
and other factors
c. Hypertension is always linked to the Y chromosomes and
environmental factors
d. Y chromosomes as hemophilia is associated with the X-
chromosomes. Answer: a. Turners' syndrome is a disorder in which
a female has completely or partially missing X chromosomes
◉ What is the primary system responsible for maintaining fluid
homeostasis within the body?
a. Interatrial fluid (IAF)18 | Page
b. Extra natriuretic fluid [ENF)
c. D-type diastolic peptides (DDP)
d. Renin-angiotensin-aldosterone system [RAAS]. Answer: d. Renin-
angiotensin-aldosterone system [RAAS]
,◉ What is a symptom found in patients with stage 1 Lyme disease?
a. Tremors
b. Bull's eye rash
c. Nausea
d. Swollen lymph nodes. Answer: b. Bull's eye rash
◉ What are the characteristics of helper T cells?
a. They activate B cells and produce small cells called cytokines.
b. They destroy infected cells by producing proteins targeting cell
membranes.
c. They are non-responsive during active infections.
d. They bind to infected cells and are activated by cytokines..
Answer: a. They activate B cells and produce small cells called
cytokines.
◉ What are two types of benign tumors? Choose 2 answers
a. Adenoma
b. Adenocarcinoma
c. Non-Hodgkin lymphoma
d. Osteoma. Answer: a. Adenoma
d. Osteoma
,◉ Which term describes a solution such as 0.9% NaCl (normal
saline) relative to red blood cells?
a. Hypotonic
b. Isotonic
c. Hypertonic
d. Exotonic. Answer: b. Isotonic
◉ A patient's record indicates treatment via cryoablation. For
which type of cancer is this patient being treated?
a. Breast cancer
b. Prostate cancer
c. Ovarian cancer
d. Testicular cancer. Answer: b. Prostate cancer
◉ A female patient presents with chronic dyspareunia, pelvic pain,
increased abdominal girth, fever, and vomiting. After an HE4
test and positive abdominal ultrasound. Which condition is
described?
a. Ovarian tumor
b. Dysmenorrhea
c. Pelvic inflammatory disease (PID)
d. Benign fibroadenoma. Answer: a. Ovarian tumor
, ◉ A patient presents with decreased alertness, mental confusion,
skin that is pale and scaly, weight loss, easy bruising or
bleeding, and decreased urine output. Which condition is this
patient showing signs?
a. Renal calculi
b. End-stage renal disease
c. Hydronephrosis
d. Polycystic kidney disease. Answer: b. End-stage renal disease
◉ Which is a common cause of delayed puberty?
a. Urinary tract infection
b. Premature birth
c. Chronic illness
d. High-fat die. Answer: c. Chronic illness
◉ What is a clinical presentation of Human Papillomavirus
(HPV)?
a. Diarrhea
b. Condyloma acuminata
c. Penile edema
d. Urethritis. Answer: b. Condyloma acuminata
ASSESSMENT COMPREHENSIVE EXAM 2026
◉ Which accurately describes a chromosomal alteration?
a. Turners' syndrome is a disorder in which a female has completely
or partially missing X chromosomes
b. Type 2 DM (T2DM) is caused by family history, behavior,
and other factors
c. Hypertension is always linked to the Y chromosomes and
environmental factors
d. Y chromosomes as hemophilia is associated with the X-
chromosomes. Answer: a. Turners' syndrome is a disorder in which
a female has completely or partially missing X chromosomes
◉ What is the primary system responsible for maintaining fluid
homeostasis within the body?
a. Interatrial fluid (IAF)18 | Page
b. Extra natriuretic fluid [ENF)
c. D-type diastolic peptides (DDP)
d. Renin-angiotensin-aldosterone system [RAAS]. Answer: d. Renin-
angiotensin-aldosterone system [RAAS]
,◉ What is a symptom found in patients with stage 1 Lyme disease?
a. Tremors
b. Bull's eye rash
c. Nausea
d. Swollen lymph nodes. Answer: b. Bull's eye rash
◉ What are the characteristics of helper T cells?
a. They activate B cells and produce small cells called cytokines.
b. They destroy infected cells by producing proteins targeting cell
membranes.
c. They are non-responsive during active infections.
d. They bind to infected cells and are activated by cytokines..
Answer: a. They activate B cells and produce small cells called
cytokines.
◉ What are two types of benign tumors? Choose 2 answers
a. Adenoma
b. Adenocarcinoma
c. Non-Hodgkin lymphoma
d. Osteoma. Answer: a. Adenoma
d. Osteoma
,◉ Which term describes a solution such as 0.9% NaCl (normal
saline) relative to red blood cells?
a. Hypotonic
b. Isotonic
c. Hypertonic
d. Exotonic. Answer: b. Isotonic
◉ A patient's record indicates treatment via cryoablation. For
which type of cancer is this patient being treated?
a. Breast cancer
b. Prostate cancer
c. Ovarian cancer
d. Testicular cancer. Answer: b. Prostate cancer
◉ A female patient presents with chronic dyspareunia, pelvic pain,
increased abdominal girth, fever, and vomiting. After an HE4
test and positive abdominal ultrasound. Which condition is
described?
a. Ovarian tumor
b. Dysmenorrhea
c. Pelvic inflammatory disease (PID)
d. Benign fibroadenoma. Answer: a. Ovarian tumor
, ◉ A patient presents with decreased alertness, mental confusion,
skin that is pale and scaly, weight loss, easy bruising or
bleeding, and decreased urine output. Which condition is this
patient showing signs?
a. Renal calculi
b. End-stage renal disease
c. Hydronephrosis
d. Polycystic kidney disease. Answer: b. End-stage renal disease
◉ Which is a common cause of delayed puberty?
a. Urinary tract infection
b. Premature birth
c. Chronic illness
d. High-fat die. Answer: c. Chronic illness
◉ What is a clinical presentation of Human Papillomavirus
(HPV)?
a. Diarrhea
b. Condyloma acuminata
c. Penile edema
d. Urethritis. Answer: b. Condyloma acuminata
