ANTICOAGULATION NAPLEX TEST QUESTIONS AND
FULLY CORRECTT ANSWERS
The most frequent adverse reaction to anticoagulants is ANSWER Bleeding.
The inhibitors of ANSWER Factors 2, 7, 9, and 10 are warfarin.
ANSWER Apixaban, Rivaroxaban, and Edoxaban are direct factor Xa
inhibitors.
Antithrombin-based indirect Factor Xa inhibitors: ANSWER Fondaparinux
Direct thrombin inhibitors: bivalirudin, dabigatran, argatroban, and ANSWER
IV
Inhibitors of factors Xa and IIa: ANSWER UFH-heparin (equal action of Xa
and IIa)
LMWH: dalteparin and enoxaparin. Xa activity is higher than IIa activity.
IV anticoagulants used for VTE/PE (treatments and prophylaxis) and ANSWER
ACS treatment
Oral anticoagulants are primarily used in the treatment and prevention of
ANSWER VTE/PE.
Afib: Preventing strokes
, When is warfarin a better option than DOAC? Stenosis of the mitra
A mechanical valve
Antiphospholipid
The ANSWER indication and kidney/liver function are the basis for adjusting
the dosage of DOAC.
The American College of Chest Physicians (ANSWER) and the American
College of Cardiology/American Heart Association (ACC/AHA) have
established anticoagulant recommendations.
ANSWER Coumadin, Jantoven, and Vitamin K antagonist are alternate names
for warfarin.
What is AT, or antithrombin? The response Endogenous anticoagulant that
keeps the blood flowing to keep clots from forming
When anticoagulants attach to antithrombin, they cause a conformational shift
that raises AT activity. The response is UFH LMWH Fondaparinux.
Acute ischaemic stroke is treated with fibronolytics.
STEMI
Stroke or STEMI: if blood flow is not quickly restored, the patient may not
survive.
ANSWER: Antipaltelet medications used only in ACS and to stop strokes from
happening again.
Not for PE or DVT
FULLY CORRECTT ANSWERS
The most frequent adverse reaction to anticoagulants is ANSWER Bleeding.
The inhibitors of ANSWER Factors 2, 7, 9, and 10 are warfarin.
ANSWER Apixaban, Rivaroxaban, and Edoxaban are direct factor Xa
inhibitors.
Antithrombin-based indirect Factor Xa inhibitors: ANSWER Fondaparinux
Direct thrombin inhibitors: bivalirudin, dabigatran, argatroban, and ANSWER
IV
Inhibitors of factors Xa and IIa: ANSWER UFH-heparin (equal action of Xa
and IIa)
LMWH: dalteparin and enoxaparin. Xa activity is higher than IIa activity.
IV anticoagulants used for VTE/PE (treatments and prophylaxis) and ANSWER
ACS treatment
Oral anticoagulants are primarily used in the treatment and prevention of
ANSWER VTE/PE.
Afib: Preventing strokes
, When is warfarin a better option than DOAC? Stenosis of the mitra
A mechanical valve
Antiphospholipid
The ANSWER indication and kidney/liver function are the basis for adjusting
the dosage of DOAC.
The American College of Chest Physicians (ANSWER) and the American
College of Cardiology/American Heart Association (ACC/AHA) have
established anticoagulant recommendations.
ANSWER Coumadin, Jantoven, and Vitamin K antagonist are alternate names
for warfarin.
What is AT, or antithrombin? The response Endogenous anticoagulant that
keeps the blood flowing to keep clots from forming
When anticoagulants attach to antithrombin, they cause a conformational shift
that raises AT activity. The response is UFH LMWH Fondaparinux.
Acute ischaemic stroke is treated with fibronolytics.
STEMI
Stroke or STEMI: if blood flow is not quickly restored, the patient may not
survive.
ANSWER: Antipaltelet medications used only in ACS and to stop strokes from
happening again.
Not for PE or DVT
