MOCK CG (ASCP) CERTIFICATION
EXAM 1 - PART 1 AND 2 LATEST EXAM
ACTUAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS
|ALREADY GRADED A+
A digital image is made up of:
a. Lines
b. Pixels
c. Arcs
d. Tangents - CORRECT ANSWER ✔✔- Pixels
High resolution banding relies upon?
a. 850 bands per haploid set
b. 850 bands per diploid set
c. 850 bands per chromosome
d. a and b - CORRECT ANSWER ✔✔- 850 bands per haploid set
What is the modal number for a triploid karyotype?
a. 60
b. 66
c. 69
d. 70 - CORRECT ANSWER ✔✔- 69
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,The centromere index:
a. Refers to the total number of centromeres present in a metaphase plate.
b. Is the ratio of the short arm to the overall length of a chromosome.
c. Refers to the ratio of the to the long arm of a particular chromosome.
d. Is the ratio of the long arm to the overall length of a chromosome. - CORRECT
ANSWER ✔✔- Is the ratio of the short arm to the overall length of a chromosome.
A cell with three copies of each chromosome is classified as:
a. Mosaic
b. Haploid
c. Trisomic
d. Triploid - CORRECT ANSWER ✔✔- Triploid
A couple is referred to a clinical cytogenetics laboratory due to a prior history of
multiple spontaneous abortions. A peripheral blood specimen is obtained for
constitutional chromosome analysis, and it is discovered that the male is a carrier
of a Robertsonian translocation [der(13;14)(q10;q10)] while the female is
chromosomally normal. What is the likelihood that the next conception will be a
miscarriage? (Assume that all viable zygotes, even in phenotypical abnormal, will
come to term.)
a. 33%
b. 25%
c. 100%
d. 50% - CORRECT ANSWER ✔✔- 50%
The structural rearrangement involving the loss of one chromosome arm and the
duplication of the other is a (an):
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,a. Deletion
b. Ring
c. Inversion
d. Reciprocal translocation
e. Isochromosome - CORRECT ANSWER ✔✔- Isochromosome
Which of the following karyotypes would you expect to be associated with the
most severe degree of mental retardation?
a. 47,XXY
b. 48,XXXY
c. 47,XYY
d. 46,XX - CORRECT ANSWER ✔✔- 48,XXXY
A woman with a 47,XXX karyotype marries a karyotypically normal male. What
are the theoretical karyotypes?
a. 46,XX;46,XY;47,XXX;47,XXY in equal proportions
b. 47,XXY and 47,XXX in unequal proportions
c. 46,XY; 47,XXX; 47,XXY in unequal proportions
d. 47,XXX and 47,XXY in equal proportions - CORRECT ANSWER ✔✔-
46,XX;46,XY;47,XXX;47,XXY in equal proportions
This syndrome is characterized by a deletion of 4p16. This syndrome is also called
the "Greek Warrior Helmet" syndrome.
a. Alagille syndrome
b. DiGeorge syndrome
c. Angelman syndrome
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, d. Wolf-Hirschhorn syndrome - CORRECT ANSWER ✔✔- Wolf-Hirschhorn
syndrome
Trisomy 13, a severe disorder characterized by cleft lip palate, ocular
abnormalities, polydactyly, clenched fist, and rocker-bottom feet is also known as:
a. Robertsonian syndrome
b. Edward syndrome
c. Patau syndrome
d. Down syndrome - CORRECT ANSWER ✔✔- Patau syndrome
Rearrangements of 14q11, 7p15, and 7q35 are characteristically found in:
a. Myeloid malignances
b. Lymphoid malignances
c. T-cell malignances
d. B-cell malignances - CORRECT ANSWER ✔✔- T-cell malignances
A diagnosis of true mosaicism can only be made when:
a. The abnormal cell lines are found in the same culture vessel
b. The same abnormal cell line is found in at least two independent culture vessels
c. Two or more abnormal cell lines are found the same in situ culture
d. When 46,XX and 46,XY cell lines are found in the same culture vessel -
CORRECT ANSWER ✔✔- The same abnormal cell line is found in at least two
independent culture vessels
Which of the following is the chromosome abnormality most often observed in
ANLL.
a. t(8;21)
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EXAM 1 - PART 1 AND 2 LATEST EXAM
ACTUAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS
|ALREADY GRADED A+
A digital image is made up of:
a. Lines
b. Pixels
c. Arcs
d. Tangents - CORRECT ANSWER ✔✔- Pixels
High resolution banding relies upon?
a. 850 bands per haploid set
b. 850 bands per diploid set
c. 850 bands per chromosome
d. a and b - CORRECT ANSWER ✔✔- 850 bands per haploid set
What is the modal number for a triploid karyotype?
a. 60
b. 66
c. 69
d. 70 - CORRECT ANSWER ✔✔- 69
1|Page
,The centromere index:
a. Refers to the total number of centromeres present in a metaphase plate.
b. Is the ratio of the short arm to the overall length of a chromosome.
c. Refers to the ratio of the to the long arm of a particular chromosome.
d. Is the ratio of the long arm to the overall length of a chromosome. - CORRECT
ANSWER ✔✔- Is the ratio of the short arm to the overall length of a chromosome.
A cell with three copies of each chromosome is classified as:
a. Mosaic
b. Haploid
c. Trisomic
d. Triploid - CORRECT ANSWER ✔✔- Triploid
A couple is referred to a clinical cytogenetics laboratory due to a prior history of
multiple spontaneous abortions. A peripheral blood specimen is obtained for
constitutional chromosome analysis, and it is discovered that the male is a carrier
of a Robertsonian translocation [der(13;14)(q10;q10)] while the female is
chromosomally normal. What is the likelihood that the next conception will be a
miscarriage? (Assume that all viable zygotes, even in phenotypical abnormal, will
come to term.)
a. 33%
b. 25%
c. 100%
d. 50% - CORRECT ANSWER ✔✔- 50%
The structural rearrangement involving the loss of one chromosome arm and the
duplication of the other is a (an):
2|Page
,a. Deletion
b. Ring
c. Inversion
d. Reciprocal translocation
e. Isochromosome - CORRECT ANSWER ✔✔- Isochromosome
Which of the following karyotypes would you expect to be associated with the
most severe degree of mental retardation?
a. 47,XXY
b. 48,XXXY
c. 47,XYY
d. 46,XX - CORRECT ANSWER ✔✔- 48,XXXY
A woman with a 47,XXX karyotype marries a karyotypically normal male. What
are the theoretical karyotypes?
a. 46,XX;46,XY;47,XXX;47,XXY in equal proportions
b. 47,XXY and 47,XXX in unequal proportions
c. 46,XY; 47,XXX; 47,XXY in unequal proportions
d. 47,XXX and 47,XXY in equal proportions - CORRECT ANSWER ✔✔-
46,XX;46,XY;47,XXX;47,XXY in equal proportions
This syndrome is characterized by a deletion of 4p16. This syndrome is also called
the "Greek Warrior Helmet" syndrome.
a. Alagille syndrome
b. DiGeorge syndrome
c. Angelman syndrome
3|Page
, d. Wolf-Hirschhorn syndrome - CORRECT ANSWER ✔✔- Wolf-Hirschhorn
syndrome
Trisomy 13, a severe disorder characterized by cleft lip palate, ocular
abnormalities, polydactyly, clenched fist, and rocker-bottom feet is also known as:
a. Robertsonian syndrome
b. Edward syndrome
c. Patau syndrome
d. Down syndrome - CORRECT ANSWER ✔✔- Patau syndrome
Rearrangements of 14q11, 7p15, and 7q35 are characteristically found in:
a. Myeloid malignances
b. Lymphoid malignances
c. T-cell malignances
d. B-cell malignances - CORRECT ANSWER ✔✔- T-cell malignances
A diagnosis of true mosaicism can only be made when:
a. The abnormal cell lines are found in the same culture vessel
b. The same abnormal cell line is found in at least two independent culture vessels
c. Two or more abnormal cell lines are found the same in situ culture
d. When 46,XX and 46,XY cell lines are found in the same culture vessel -
CORRECT ANSWER ✔✔- The same abnormal cell line is found in at least two
independent culture vessels
Which of the following is the chromosome abnormality most often observed in
ANLL.
a. t(8;21)
4|Page
