Psychopharmacology: Drugs, the Brain, and Behavior, 4th Edition – Test Bank & Study Guide with Answers

MedConnoisseur Files:
v v

, MedConnoisseur Files:
v v




Chapter 1: Principles of Pharmacology
v v v v




MultiplevChoice

1. refer(s)vtovspecificvmolecularvchangesvthatvoccurvwhenvavdrugvbindsvtovavpart
icularvtargetvsitevorvreceptor,vwhile
arevthevresultingvwidespreadvalterationsvinvfunction.
a. Drugvaction;vtherapeuticveffects
b. Sideveffects;vdrugveffects
c. Therapeuticveffects;vsideveffects
d. Drugvaction;vdrugveffects
Answer:vd
TextbookvReference:vPharmacology:vThevSciencevofvDrugvAction

2. Aftervdrugvadministrationvhasvoccurred,vthevamountvofvdrugvinvthevbloodvthatvisvfreevtovb
indvatvspecificvtargetvsitesvisvreferredvtovas
a. thevtherapeuticvdose.
b. first-passveffects.
c. bioavailability.
d. ED50.
Answer:vc
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

3. Thevspecificvmolecularvchangesvthatvoccurvwhenvavdrugvbindsvtovavparticularvtargetvsitevo
rvreceptorvarevreferredvtovas
a. drugveffects.
b. drugvaction.
c. sideveffects.
d. placeboveffects.
Answer:vb
TextbookvReference:vPharmacology:vThevSciencevofvDrugvAction

4. Whichvofvthevfollowingvisvnotvavpossiblevexplanationvforvplaceboveffects?
a. Pavlovianvconditioning
b. Geneticvvariation
c. Drugvcompetition
d. Expectationvofvoutcome
Answer:vc
TextbookvReference:vPharmacology:vThevSciencevofvDrugvAction




WWW.THENURSINGMASTERY.COM
Pagev1vofv247

, MedConnoisseur Files:
v v




5. The administrationvofvoxytocinvhasvbeenvproposedvasvavtreatmentvforvautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:vc
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

6. Whichvfactorvdoesvnotvaffectvthevpharmacokineticsvofvavdrug?
a. Routevofvadministration
b. Lipidvsolubility
c. Depotvbinding
d. Drugvaction
Answer:vd
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

7. First-passvmetabolismvoccursvwhenvdrugsvarevtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:va
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

8. Thevareavpostremavisvonevareavinvthevbrainvwherevthe isvnotvcomplete.
a. cerebrospinalvfluid
b. blood–brainvbarrier
c. choroidvplexus
d. phospholipidvmembrane
Answer:vb
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

9. First-passvmetabolismvoccursvwithvorallyvadministeredvdrugsvbecause
a. theirvabsorptionvisvslowedvbyvfood.
b. drugsvabsorbedvintovthevbloodstreamvfromvthevstomachvgovtovthevlivervonvthevwayvtovg
eneralvcirculation.
c. drugsvmustvfirstvsurvivevthevacidicvenvironmentvofvthevstomach.
d. salivaryvenzymesvinvthevmouthvbeginvthevprocessvofvmetabolism.
Answer:vb
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

10. Toxicvsubstancesvinvthevbloodvtriggervavvomitingvresponsevbyvactivatingvthe
a. blood–brainvbarrier.
b. choroidvplexus.
c. areavpostrema.
d. medianveminence.



WWW.THENURSINGMASTERY.COM
Pagev2vofv247

, MedConnoisseur Files:
v v




Answer:vc
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

11. Drugsvadministeredv_ havevthevmostvrapidvonsetvofvaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:vd
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

12. Ionizationvofvavdrugvdependsvonvthe ofvthevsolutionvandvthe
ofvthevdrug.
a. pH;vpKa
b. pKa;vpH
c. concentration;vlipidvsolubility
d. pH;vconcentration
Answer:va
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

13. Thevabsorptionvofvavdrugvdependsvonvallvofvthevfollowingvexcept
a. lipidvsolubility.
b. ionization.
c. bodyvtemperature.
d. thevconcentrationvofvthevdrug.
Answer:vc
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

14. Drugsvthatvare shouldvbevavoidedvbyvwomenvofvchildbearingvage.
a. teratogenic
b. ablevtovcrossvthevplacentalvbarrier
c. psychoactive
d. highlyvlipid-soluble
Answer:va
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

15. Agentsvthatvinducevdevelopmentalvabnormalitiesvinvavfetusvarevknownvas
a. psychoactivevdrugs.
b. illicitvdrugs.
c. teratogens.
d. placentalvdrugs.
Answer:vc
TextbookvReference:vPharmacokineticvFactorsvDeterminingvDrugvAction

16. Depotvbindingvisvsaidvtovoccurvwhenvdrugs
a. bindvtovtheirvtargetvsites.



WWW.THENURSINGMASTERY.COM
Pagev3vofv247