MCB 100 Exam 3 Material Questions With Complete
Solutions
The antibody-binding site of an antibody is made up of
a. The light chains only
b. The variable regions of the heavy chains
c. One heavy chain
d. The variable regions of both light and heavy chains
e. Portions of both of the heavy chains only
d. The variable regions of both light and heavy chains
Most often, antigens are composed of __________
a. Glycoproteins
b. Polysaccharides
c. Lipids
d. Nucleic acids
a. Glycoproteins
Toxins and bacterial parts are considered _____ antigen because
they are present outside of the body's cells
a. Exogenous
b. Autoantigen
c. Epitopes
d. Endogenous
a. Exogenous
What is the purpose of an MHC class I protein?
a. MHC class I proteins display epitopes from endogenous
antigen
,b. MHC class I molecules display epitopes from exogenous
antigen
c. MHC class I proteins break down endogenous antigen
d. MHC class I proteins bind antibodies
a. MHC class I proteins display epitopes from endogenous
antigen
Which cells possess MHC class II proteins?
a. Red blood cells
b. Nucleated cells
c. Antigen-presenting cells
d. All white blood cells
c. Antigen-presenting cells
In which location within the cell are epitopes bound to MHC
class I proteins?
a. Golgi body
b. Nucleus
c. Cytoplasm
d. Endoplasmic reticulum
d. Endoplasmic reticulum
Which organelle is responsible for the degradation of exogenous
antigen within an antigen-presenting cell?
a. Phagolysosome
b. Ribosome
c. Nucleus
d. Endoplasmic reticulum
a. Phagolysosome
,Which of the following cells is included as an antigen-
presenting cell?
a. Macrophages
b. Hepatocytes
c. Red blood cells
d. Platelets
a. Macrophages
Which of the following is an exogenous antigen?
a. The malaria parasite inside a red blood cell
b. A bacterium outside a cell
c. A bacterium inside a cell
d. A non-infected human cell
e. A virus inside a cell
b. A bacterium outside a cell
What is the result when a dendritic cell phagocytizes a microbe
and processes it?
a. Suppression of the immune response to the microbe
b. Activation of the dendritic cell to become a plasma cell
c. Display of microbial fragments with CD8 glycoproteins
d. Display of epitope-MHC I complexes on the surface of the
cell
e. Display of microbial epitope-MHC II complexes on the cell
surface
e. Display of microbial epitope-MHC II complexes on the cell
surface
, IgE antibodies are best described as
a. The antibodies found in body secretions.those involved in
complement activation
b. A cause of basophil and eosinophil degranulation
c. The trigger for antibody-dependent cellular toxicity (ADCC)
d. The most common type of antibody in the blood during the
initial phases of an immune response
b. A cause of basophil and eosinophil degranulation
The perforin-granzyme pathway involves
a. Presenting the foreign antigen to B cells
b. The production of fever, which kills the pathogen
c. The production of special cell-killing proteins that act on
infected or abnormal cells
d. The production of antibodies toward the invading pathogen
e. Binding CD95L to infected cells, which eventually leads to
cell apoptosis
c. The production of special cell-killing proteins that act on
infected or abnormal cells
Apoptosis is the process of __________
a. Multiplying into a clone repertoire
b. Presenting epitope in an MHC protein
c. Differentiating into a regulatory T cell
d. Programmed cell death
d. Programmed cell death
Clonal deletion occurs in the __________
a. Thymus
Solutions
The antibody-binding site of an antibody is made up of
a. The light chains only
b. The variable regions of the heavy chains
c. One heavy chain
d. The variable regions of both light and heavy chains
e. Portions of both of the heavy chains only
d. The variable regions of both light and heavy chains
Most often, antigens are composed of __________
a. Glycoproteins
b. Polysaccharides
c. Lipids
d. Nucleic acids
a. Glycoproteins
Toxins and bacterial parts are considered _____ antigen because
they are present outside of the body's cells
a. Exogenous
b. Autoantigen
c. Epitopes
d. Endogenous
a. Exogenous
What is the purpose of an MHC class I protein?
a. MHC class I proteins display epitopes from endogenous
antigen
,b. MHC class I molecules display epitopes from exogenous
antigen
c. MHC class I proteins break down endogenous antigen
d. MHC class I proteins bind antibodies
a. MHC class I proteins display epitopes from endogenous
antigen
Which cells possess MHC class II proteins?
a. Red blood cells
b. Nucleated cells
c. Antigen-presenting cells
d. All white blood cells
c. Antigen-presenting cells
In which location within the cell are epitopes bound to MHC
class I proteins?
a. Golgi body
b. Nucleus
c. Cytoplasm
d. Endoplasmic reticulum
d. Endoplasmic reticulum
Which organelle is responsible for the degradation of exogenous
antigen within an antigen-presenting cell?
a. Phagolysosome
b. Ribosome
c. Nucleus
d. Endoplasmic reticulum
a. Phagolysosome
,Which of the following cells is included as an antigen-
presenting cell?
a. Macrophages
b. Hepatocytes
c. Red blood cells
d. Platelets
a. Macrophages
Which of the following is an exogenous antigen?
a. The malaria parasite inside a red blood cell
b. A bacterium outside a cell
c. A bacterium inside a cell
d. A non-infected human cell
e. A virus inside a cell
b. A bacterium outside a cell
What is the result when a dendritic cell phagocytizes a microbe
and processes it?
a. Suppression of the immune response to the microbe
b. Activation of the dendritic cell to become a plasma cell
c. Display of microbial fragments with CD8 glycoproteins
d. Display of epitope-MHC I complexes on the surface of the
cell
e. Display of microbial epitope-MHC II complexes on the cell
surface
e. Display of microbial epitope-MHC II complexes on the cell
surface
, IgE antibodies are best described as
a. The antibodies found in body secretions.those involved in
complement activation
b. A cause of basophil and eosinophil degranulation
c. The trigger for antibody-dependent cellular toxicity (ADCC)
d. The most common type of antibody in the blood during the
initial phases of an immune response
b. A cause of basophil and eosinophil degranulation
The perforin-granzyme pathway involves
a. Presenting the foreign antigen to B cells
b. The production of fever, which kills the pathogen
c. The production of special cell-killing proteins that act on
infected or abnormal cells
d. The production of antibodies toward the invading pathogen
e. Binding CD95L to infected cells, which eventually leads to
cell apoptosis
c. The production of special cell-killing proteins that act on
infected or abnormal cells
Apoptosis is the process of __________
a. Multiplying into a clone repertoire
b. Presenting epitope in an MHC protein
c. Differentiating into a regulatory T cell
d. Programmed cell death
d. Programmed cell death
Clonal deletion occurs in the __________
a. Thymus
