MCB4271 Final Exam, MCB4271 Test Bank,
Molecular and Cell Biology, MCB4271 Questions
and Answers, Advanced Biology Exam,
MCB4271 Study Guide, Biology Final Exam Prep
True or False: All antibacterial drugs are antibiotics. -
.....ANSWER ...✔✔ False
When was the first antibiotic discovered? - .....ANSWER
...✔✔ 1928
Antimicrobial resistance - .....ANSWER ...✔✔ The
ability of a microbe to stop an antimicrobial from
working against it, resulting in standard treatments
becoming ineffective and infections becoming persistent.
What types of organisms can cause AMR? - .....ANSWER
...✔✔ Bacteria, fungi, viruses, parasites, pests, weeds
What's a type of "resistance" found in humans? -
.....ANSWER ...✔✔ Cancers being resistant to
chemotherapy
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Community-acquired infection - .....ANSWER ...✔✔
Infection acquired in the community (gym, subway,
classroom, etc.), not in a hospital
Nosocomial infections - .....ANSWER ...✔✔ Hospital
acquired infections (nursing home, clinic, etc.)
Most AMR infections are ___. - .....ANSWER ...✔✔
Community-acquired
Most deaths due to AMR infections are ___. -
.....ANSWER ...✔✔ Nosocomial
AMR occurs ___. - .....ANSWER ...✔✔ Naturally
AMR leads to: - .....ANSWER ...✔✔ Longer hospital
stays, higher medical costs, increased mortality
Describe the trend in percentage of ABR infections. -
.....ANSWER ...✔✔ Annually, the number of bacterial
infections stays pretty constant; percentage of ABR
infections keeps increasing.
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How does ABR lead to higher medical costs? -
.....ANSWER ...✔✔ 1. Cost of prescription antibiotics
2. Prolonged hospital stays
3. Additional diagnostics/lab tests
4. Need to hire specialists
Describe the relationship between numbers of resistant
bacteria and numbers of novel antibiotics. - .....ANSWER
...✔✔ Resistant bacteria - increasing
Antibiotics - almost 0
How long does it take for an antibiotic to develop
clinical resistance? - .....ANSWER ...✔✔ 8 years
What are 7 major factors contributing to AMR in
healthcare? - .....ANSWER ...✔✔ 1. Misuse of
antibiotics
2. Use of antibiotics in healthcare
3. Lack of antibiotics (untreated person with resistant
bacteria poses a risk to others)
4. Poor sanitation/personal hygiene
5. Inadequate infection controls in healthcare settings
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6. Limiting exposure to microbes
7. Antimicrobials in personal hygiene products
What are 3 factors contributing to antibiotic misuse? -
.....ANSWER ...✔✔ 1. Underuse - not finishing
prescriptions
2. Use - using antibiotics increases risks for other
infections (e.g., C. diff)
3. Overuse - 25 to 75% prescriptions; given when not
needed, continued when not necessary, wrong dose,
wrong antibiotic
Describe how population growth leads to antibiotic
resistance. - .....ANSWER ...✔✔ Increase in global
population --> increase in food demand --> increased
animal farming --> increased disease transmission on
farms --> increased use of antibiotics --> increased ABR
--> increased probability of humans encountering low
levels of antibiotics --> increased ABR
What are 2 reasons for antibiotics being used for
farming? - .....ANSWER ...✔✔ 1. Growth promoters -
either inhibit gut bacteria, which leads to increased
energy uptake, or kill pathogenic bacteria, resulting in
more energy for growth