Samenvatting oncologie
Inhoudsopgave Oncologie
1 Inleiding............................................................................................................... 4
1.1 Wat?.............................................................................................................. 4
1.2 Cijfers (2022)................................................................................................. 4
2 Ontstaan.............................................................................................................. 4
2.1 Risicofactoren................................................................................................ 4
2.2 Preventie....................................................................................................... 4
2.2.1 Primair..................................................................................................... 4
2.2.2 Secundair................................................................................................ 4
2.2.3 Tertiair..................................................................................................... 4
3 Cel en tumorbiologie........................................................................................... 5
3.1 Algemeen...................................................................................................... 5
3.2 Celcyclus....................................................................................................... 5
3.2.1 Interfase.................................................................................................. 5
3.2.2 Mitose...................................................................................................... 5
3.2.3 Regulatie................................................................................................. 5
3.3 Carcinogenese............................................................................................... 6
3.3.1 Initiatie.................................................................................................... 6
3.3.2 Promotie.................................................................................................. 6
3.3.3 Progressie................................................................................................ 6
3.3.4 Metastase (Uitzaaiing)............................................................................. 6
4 Genen.................................................................................................................. 6
5 Goedaardige vs. Kwaadaardige tumoren.............................................................7
5.1 Kenmerken.................................................................................................... 7
5.2 Differentatiegraad......................................................................................... 7
5.3 Metastasering................................................................................................ 7
6 Classificatie tumoren........................................................................................... 7
6.1 Doel............................................................................................................... 7
6.2 Stadia............................................................................................................ 7
6.3 TNM-classificatie........................................................................................... 8
6.4 Opmerkingen................................................................................................. 8
7 Begrippen............................................................................................................ 8
7.1 Remissie........................................................................................................ 8
7.2 Recidief......................................................................................................... 8
7.3 Progressie...................................................................................................... 8
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,8 Diagnostiek......................................................................................................... 8
8.1 Doel............................................................................................................... 8
8.2 Hoe?.............................................................................................................. 9
9 Erfelijkheid........................................................................................................... 9
10 Oncologische zorgprogramma’s Vlaanderen.....................................................9
11 Keuze behandeling + MOC.............................................................................. 10
12 Hoe behandelen.............................................................................................. 10
13 Behandelingen................................................................................................. 10
13.1 Chirurgie.................................................................................................... 10
13.1.1 Indicaties............................................................................................. 10
13.1.2 Aandachtspunten................................................................................ 11
13.2 Radiotherapie............................................................................................ 11
13.2.1 Wat?.................................................................................................... 11
13.2.2 Indicaties............................................................................................. 11
13.2.3 Hoe?.................................................................................................... 11
13.2.4 Uitwendige- en inwendige bestraling..................................................11
13.2.5 Nevenwerkingen + preventie..............................................................12
13.2.6 Evoluties.............................................................................................. 14
13.3 Anti-hormonale behandeling.....................................................................14
13.3.1 Hormoon............................................................................................. 14
13.3.2 Hormonen en tumoren........................................................................14
13.3.3 Indicatie.............................................................................................. 14
13.3.4 Werking............................................................................................... 15
13.3.5 Nevenwerkingen................................................................................. 15
13.3.6 Impact op seksualiteit.........................................................................15
13.3.7 Therapie – (on)trouw...........................................................................15
13.4 Chemotherapie.......................................................................................... 15
13.4.1 Cytostatica wat?.................................................................................. 15
13.4.2 Begrippen............................................................................................ 16
13.4.3 Werking............................................................................................... 16
13.4.4 Interactie andere medicatie................................................................16
13.4.5 Indicaties............................................................................................. 16
13.4.6 Toedieningswegen............................................................................... 16
13.4.7 Verloop behandeling........................................................................... 16
13.4.8 Nevenwerkingen................................................................................. 17
13.4.9 Onszelf beschermen tegen cytostatica?..............................................19
13.4.10 Beroepsmatige blootstelling..............................................................20
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, 13.4.11 Algemene voorzorgsmaatregelen.....................................................20
13.4.12 Veiligheidsvoorschriften cytostatica PO.............................................20
13.5 Targeted therapies.................................................................................... 20
13.5.1 Wat?.................................................................................................... 20
13.5.2 Voor welke tumoren............................................................................ 20
13.5.3 Indicaties............................................................................................. 21
13.5.4 Nevenwerkingen................................................................................. 21
13.6 Immunotherapie........................................................................................ 22
13.6.1 Toepassing........................................................................................... 22
13.6.2 Nevenwerkingen................................................................................. 22
14 Oncologie en seksualiteit en intimiteit............................................................22
14.1 Hoe gesprek aangaan?.............................................................................. 22
14.2 Praktische info........................................................................................... 23
14.3 Doorverwijzen........................................................................................... 23
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Inhoudsopgave Oncologie
1 Inleiding............................................................................................................... 4
1.1 Wat?.............................................................................................................. 4
1.2 Cijfers (2022)................................................................................................. 4
2 Ontstaan.............................................................................................................. 4
2.1 Risicofactoren................................................................................................ 4
2.2 Preventie....................................................................................................... 4
2.2.1 Primair..................................................................................................... 4
2.2.2 Secundair................................................................................................ 4
2.2.3 Tertiair..................................................................................................... 4
3 Cel en tumorbiologie........................................................................................... 5
3.1 Algemeen...................................................................................................... 5
3.2 Celcyclus....................................................................................................... 5
3.2.1 Interfase.................................................................................................. 5
3.2.2 Mitose...................................................................................................... 5
3.2.3 Regulatie................................................................................................. 5
3.3 Carcinogenese............................................................................................... 6
3.3.1 Initiatie.................................................................................................... 6
3.3.2 Promotie.................................................................................................. 6
3.3.3 Progressie................................................................................................ 6
3.3.4 Metastase (Uitzaaiing)............................................................................. 6
4 Genen.................................................................................................................. 6
5 Goedaardige vs. Kwaadaardige tumoren.............................................................7
5.1 Kenmerken.................................................................................................... 7
5.2 Differentatiegraad......................................................................................... 7
5.3 Metastasering................................................................................................ 7
6 Classificatie tumoren........................................................................................... 7
6.1 Doel............................................................................................................... 7
6.2 Stadia............................................................................................................ 7
6.3 TNM-classificatie........................................................................................... 8
6.4 Opmerkingen................................................................................................. 8
7 Begrippen............................................................................................................ 8
7.1 Remissie........................................................................................................ 8
7.2 Recidief......................................................................................................... 8
7.3 Progressie...................................................................................................... 8
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,8 Diagnostiek......................................................................................................... 8
8.1 Doel............................................................................................................... 8
8.2 Hoe?.............................................................................................................. 9
9 Erfelijkheid........................................................................................................... 9
10 Oncologische zorgprogramma’s Vlaanderen.....................................................9
11 Keuze behandeling + MOC.............................................................................. 10
12 Hoe behandelen.............................................................................................. 10
13 Behandelingen................................................................................................. 10
13.1 Chirurgie.................................................................................................... 10
13.1.1 Indicaties............................................................................................. 10
13.1.2 Aandachtspunten................................................................................ 11
13.2 Radiotherapie............................................................................................ 11
13.2.1 Wat?.................................................................................................... 11
13.2.2 Indicaties............................................................................................. 11
13.2.3 Hoe?.................................................................................................... 11
13.2.4 Uitwendige- en inwendige bestraling..................................................11
13.2.5 Nevenwerkingen + preventie..............................................................12
13.2.6 Evoluties.............................................................................................. 14
13.3 Anti-hormonale behandeling.....................................................................14
13.3.1 Hormoon............................................................................................. 14
13.3.2 Hormonen en tumoren........................................................................14
13.3.3 Indicatie.............................................................................................. 14
13.3.4 Werking............................................................................................... 15
13.3.5 Nevenwerkingen................................................................................. 15
13.3.6 Impact op seksualiteit.........................................................................15
13.3.7 Therapie – (on)trouw...........................................................................15
13.4 Chemotherapie.......................................................................................... 15
13.4.1 Cytostatica wat?.................................................................................. 15
13.4.2 Begrippen............................................................................................ 16
13.4.3 Werking............................................................................................... 16
13.4.4 Interactie andere medicatie................................................................16
13.4.5 Indicaties............................................................................................. 16
13.4.6 Toedieningswegen............................................................................... 16
13.4.7 Verloop behandeling........................................................................... 16
13.4.8 Nevenwerkingen................................................................................. 17
13.4.9 Onszelf beschermen tegen cytostatica?..............................................19
13.4.10 Beroepsmatige blootstelling..............................................................20
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, 13.4.11 Algemene voorzorgsmaatregelen.....................................................20
13.4.12 Veiligheidsvoorschriften cytostatica PO.............................................20
13.5 Targeted therapies.................................................................................... 20
13.5.1 Wat?.................................................................................................... 20
13.5.2 Voor welke tumoren............................................................................ 20
13.5.3 Indicaties............................................................................................. 21
13.5.4 Nevenwerkingen................................................................................. 21
13.6 Immunotherapie........................................................................................ 22
13.6.1 Toepassing........................................................................................... 22
13.6.2 Nevenwerkingen................................................................................. 22
14 Oncologie en seksualiteit en intimiteit............................................................22
14.1 Hoe gesprek aangaan?.............................................................................. 22
14.2 Praktische info........................................................................................... 23
14.3 Doorverwijzen........................................................................................... 23
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