ONCOLOGY CERTIFIED NURSE (OCN) Complete
Questions And Correct Answers|Already Graded
A+|Brand New Version
1. Which chemotherapy agent is most strongly associated with
cardiotoxicity?
A. Cyclophosphamide
B. Vincristine
C. Doxorubicin
D. Methotrexate
Doxorubicin, an anthracycline, is well known for dose-dependent
cardiotoxic effects.
2. A patient receiving cisplatin is at highest risk for which toxicity?
A. Hepatotoxicity
B. Nephrotoxicity
C. Pulmonary fibrosis
D. Cardiac arrhythmias
Cisplatin damages renal tubules, leading to nephrotoxicity.
3. The most appropriate first-line intervention for tumor lysis
syndrome is:
A. Platelet transfusion
B. Aggressive IV hydration
C. Radiation
D. Magnesium supplementation
Hydration promotes renal excretion of uric acid, potassium, and
phosphate.
,4. Which oncologic emergency is characterized by facial edema and
dyspnea when lying flat?
A. Spinal cord compression
B. Superior vena cava syndrome
C. Hypercalcemia
D. Sepsis
Obstruction of the SVC causes venous congestion in upper body
structures.
5. Filgrastim is used primarily to manage:
A. Anemia
B. Neutropenia
C. Thrombocytopenia
D. Hypercalcemia
Filgrastim stimulates neutrophil production to reduce infection risk.
6. Which type of radiation has the deepest tissue penetration?
A. Alpha particles
B. Beta particles
C. Gamma rays
D. Electron beams
Gamma rays penetrate deeply and are used in external beam
therapy.
7. The nadir is best described as:
A. The first day of chemotherapy
B. The period of lowest blood cell counts
C. Highest tumor response
, D. Peak drug concentration
Nadir typically occurs 7–14 days post-chemotherapy depending on
regimen.
8. A patient on tamoxifen should be monitored for:
A. Osteoporosis
B. Endometrial cancer
C. Adrenal insufficiency
D. Cardiac tamponade
Tamoxifen increases endometrial proliferation and cancer risk.
9. Which electrolyte abnormality is most consistent with tumor
lysis syndrome?
A. Hypokalemia
B. Hyperphosphatemia
C. Hypercalcemia
D. Hypouricemia
TLS releases intracellular phosphate, potassium, and nucleic acids.
10. A common side effect of irinotecan is:
A. Constipation
B. Diarrhea
C. Alopecia
D. Neuropathy
Irinotecan is known for severe acute and delayed diarrhea.
11. What is the earliest symptom of spinal cord compression?
Questions And Correct Answers|Already Graded
A+|Brand New Version
1. Which chemotherapy agent is most strongly associated with
cardiotoxicity?
A. Cyclophosphamide
B. Vincristine
C. Doxorubicin
D. Methotrexate
Doxorubicin, an anthracycline, is well known for dose-dependent
cardiotoxic effects.
2. A patient receiving cisplatin is at highest risk for which toxicity?
A. Hepatotoxicity
B. Nephrotoxicity
C. Pulmonary fibrosis
D. Cardiac arrhythmias
Cisplatin damages renal tubules, leading to nephrotoxicity.
3. The most appropriate first-line intervention for tumor lysis
syndrome is:
A. Platelet transfusion
B. Aggressive IV hydration
C. Radiation
D. Magnesium supplementation
Hydration promotes renal excretion of uric acid, potassium, and
phosphate.
,4. Which oncologic emergency is characterized by facial edema and
dyspnea when lying flat?
A. Spinal cord compression
B. Superior vena cava syndrome
C. Hypercalcemia
D. Sepsis
Obstruction of the SVC causes venous congestion in upper body
structures.
5. Filgrastim is used primarily to manage:
A. Anemia
B. Neutropenia
C. Thrombocytopenia
D. Hypercalcemia
Filgrastim stimulates neutrophil production to reduce infection risk.
6. Which type of radiation has the deepest tissue penetration?
A. Alpha particles
B. Beta particles
C. Gamma rays
D. Electron beams
Gamma rays penetrate deeply and are used in external beam
therapy.
7. The nadir is best described as:
A. The first day of chemotherapy
B. The period of lowest blood cell counts
C. Highest tumor response
, D. Peak drug concentration
Nadir typically occurs 7–14 days post-chemotherapy depending on
regimen.
8. A patient on tamoxifen should be monitored for:
A. Osteoporosis
B. Endometrial cancer
C. Adrenal insufficiency
D. Cardiac tamponade
Tamoxifen increases endometrial proliferation and cancer risk.
9. Which electrolyte abnormality is most consistent with tumor
lysis syndrome?
A. Hypokalemia
B. Hyperphosphatemia
C. Hypercalcemia
D. Hypouricemia
TLS releases intracellular phosphate, potassium, and nucleic acids.
10. A common side effect of irinotecan is:
A. Constipation
B. Diarrhea
C. Alopecia
D. Neuropathy
Irinotecan is known for severe acute and delayed diarrhea.
11. What is the earliest symptom of spinal cord compression?
